Berberine

Wadatacce

• Yiwuwar tasiri ga ...
• Evidencearancin shaida don kimanta inganci don ...
• Kariya & Gargaɗi na Musamman:

Berberine wani sinadari ne wanda aka samo shi a cikin tsire-tsire da yawa ciki har da barberry na Turai, zinare na zinariya, gwal na zinariya, mafi girma celandine, inabin Oregon, phellodendron, da turmeric.

Ana amfani da Berberine mafi yawa don ciwon sukari, yawan matakan cholesterol ko sauran mai (lipids) a cikin jini (hyperlipidemia), da hawan jini. Hakanan ana amfani dashi don ƙonawa, cututtukan daji, cutar hanta, da sauran yanayi amma babu kyakkyawar shaidar kimiyya don tallafawa yawancin waɗannan amfani.

Magunguna na Compwararren Bayanan Bayanai ƙimar tasiri bisa ga shaidar kimiyya bisa ga mizani mai zuwa: Inganci, Mai yuwuwa Mai Yiwuwa, Yiwuwar Tasiri, Yiwuwar Mara Inganci, Mai yiwuwa Mara Inganci, Mara Inganci, da suarancin Shaida don Rate.

Effectivenessimar tasiri don BERBERINE sune kamar haka:

Yiwuwar tasiri ga ...

• Ciwon kankara. Bincike ya nuna cewa shafa gel mai dauke da sinadarin berberine na iya rage radadi, ja, kumburi, da kuma girman gyambon ciki a cikin mutanen da ke fama da ciwon sankarar bargo.
• Ciwon suga. Berberine da alama tana ɗan rage matakan sukarin jini a cikin mutanen da ke fama da ciwon sukari. Hakanan, wasu bincike na farko sun nuna cewa shan 500 mg na berberine sau 2-3 kowace rana har zuwa watanni 3 na iya sarrafa suga na jini kamar yadda ya dace da metformin ko rosiglitazone.
• Babban matakan cholesterol ko sauran mai (lipids) a cikin jini (hyperlipidemia). Berberine na iya taimakawa rage matakan cholesterol a cikin mutanen da ke da babban cholesterol. Shan berberine har zuwa shekaru 2 da alama yana rage yawan cholesterol, ƙananan lipoprotein (LDL ko "mara kyau") cholesterol, da matakan triglyceride a cikin mutanen da ke da babban cholesterol. Idan aka kwatanta shi da daidaitattun magunguna masu rage yawan cholesterol, berberine yana haifar da irin wannan canje-canje a cikin yawan cholesterol, LDL cholesterol, da kuma babban cholesterol lipoprotein (HDL ko "mai kyau") cholesterol, kuma yana iya zama mafi alheri a rage matakan triglyceride.
• Hawan jini. Shan gram 0.9 na berberine a kowace rana tare da amlodipine na rage karfin hawan jini yana rage karfin jini na jini (lamba ta sama) da hawan jini na diastolic (lambar kasa) mafi kyau fiye da shan amlodipine shi kadai a cikin mutane masu hawan jini.
• Ciwon rashin kwayar cutar da ke haifar da kara girman ƙwai tare da kumbura (polycystic ovary syndrome ko PCOS). Bincike ya nuna cewa berberine na iya rage sukarin jini, inganta matakan cholesterol da triglyceride, rage matakan testosterone, da raguwar kugu-da-hip a cikin mata masu PCOS. Berberine na iya ma rage matakan sukarin jini kamar na metformin kuma yana iya inganta matakan cholesterol mafi kyau fiye da metformin. Babu tabbaci idan berberine ta haɓaka ƙimar ciki ko rarar haihuwar mata a cikin PCOS.

Evidencearancin shaida don kimanta inganci don ...

• Sonewa. Binciken farko ya nuna cewa sanya man shafawa wanda ya ƙunshi berberine da beta-sitosterol na iya magance ƙonewar digiri na biyu kamar yadda ya dace da magani na yau da kullun tare da azurfa sulfadiazine.
• Kamuwa da cuta daga hanji wanda ke haifar da gudawa (kwalara). Wasu bincike na farko sun nuna cewa shan berberine sulfate na iya rage gudawa da wani adadi kaɗan na mutanen da ke da cutar kwalara. Koyaya, berberine da alama baya inganta tasirin kwayar cutar tetracycline wajen magance gudawa dangane da kamuwa da cutar kwalara.
• Ciwan da ba na cutar kansa ba a cikin babban hanji da dubura (colorectal adenoma). Bincike na farko ya nuna cewa shan berberine tsawon shekaru 2 kamar yana hana sakewa daga adenomas mai launi a cikin mutanen da aka riga aka kula dasu saboda waɗannan ci gaban.
• Ciwon zuciya da ruwa sun taru a jiki (cututtukan zuciya ko CHF). Binciken farko ya nuna cewa berberine na iya rage wasu alamun kuma rage ƙimar mutuwa a cikin wasu mutane da ke fama da ciwon zuciya.
• Ciwon zuciya. Bincike ya nuna cewa shan wani takamaiman samfarin da ke dauke da sinadarin berberine da sauran sinadarai na tsawon watanni 3 yana saukar da matakan cholesterol a cikin mutanen da ke fama da cututtukan zuciya waɗanda ke da hanyar da ake kira shiga tsakani (PCI). Wannan samfurin kamar yana rage matakan cholesterol fiye da daidaitaccen magani ezetimibe, wanda ake amfani dashi don rage cholesterol. Hakanan shan wannan samfurin a haɗe tare da ƙananan ƙwayoyi na magunguna da ake kira "statins" da alama yana aiki da kyau fiye da shan ƙananan ƙwayoyi marasa ƙarfi shi kaɗai. Babu tabbacin idan tasirin wannan samfurin ya kasance ne saboda berberine, wasu kayan haɗi, ko haɗuwa. Hakanan ba a san ko wannan samfurin yana rage haɗarin manyan matsaloli masu alaƙa da zuciya a cikin mutanen da ke da cututtukan zuciya.
• Gudawa. Wasu bincike na farko sun nuna cewa shan berberine sulfate na iya rage gudawa a cikin mutanen da ke da cutar E. coli.
• Wani rukuni na rikicewar ido wanda zai haifar da rashin gani (glaucoma). Binciken farko ya nuna cewa amfani da digon ido dauke da sinadarin berberine da tetrahydrozoline ba ya rage matsewar ido ga mutanen da suke da cutar glaucoma fiye da digon ido dauke da tetrahydrozoline shi kadai.
• Cututtuka na narkewa wanda zai haifar da ulcers (Helicobacter pylori ko H. pylori). Binciken farko ya nuna cewa shan berberine ya fi maganin ranitidine wajen maganin kamuwa da cutar H. pylori. Amma itacen berberine yana da ƙarancin tasiri wajen warkar da ulceres a cikin mutane masu cutar ciki saboda H. pylori. Sauran binciken sun nuna cewa berberine na iya magance cutar H. pylori da kuma bismuth na magani idan aka haɗu tare da daidaitaccen tsarin magani uku na kamuwa da H. pylori.
• Kumburi (kumburi) na hanta sanadiyyar cutar hepatitis B (hepatitis B). Binciken farko ya nuna cewa berberine yana rage sukarin jini, kitse na jini da ake kira triglycerides, da alamomin lalata hanta ga mutanen da ke fama da ciwon sukari da hepatitis B.
• Kumburi (kumburi) na hanta sanadiyyar cutar hepatitis C virus (hepatitis C). Binciken farko ya nuna cewa berberine yana rage sukarin jini, kitse na jini da ake kira triglycerides, da alamomin cutar hanta ga mutanen da ke fama da ciwon sukari da hepatitis C.
• Rashin lafiya na dogon lokaci na manyan hanji wanda ke haifar da ciwon ciki (ciwon mara na hanji ko IBS). Bincike na farko ya nuna shan cewa berberine sau biyu a kowacce rana tsawon makonni 8 na iya rage gudawa da ciwon ciki kuma yana iya inganta rayuwar mutanen da ke dauke da cutar ta IBS.
• Alamomin rashin al'ada. Binciken farko ya nuna cewa shan hadewar sinadarin berberine da soy isoflavones na iya rage alamomin jinin haila. Koyaya, ba a bayyana ba idan berberine ya rage alamomin jinin haila idan aka yi amfani da shi shi kaɗai.
• Ofungiyar alamun bayyanar cututtukan da ke ƙara haɗarin ciwon sukari, cututtukan zuciya, da bugun jini (cututtukan rayuwa). Binciken farko ya nuna cewa berberine yana rage yawan adadin jiki (BMI), hawan jini (lamba ta sama), kitsen jini da ake kira triglycerides, da matakan sikarin jini a cikin mutanen da ke fama da ciwo na rayuwa. Hakanan yana da alama inganta ƙwarewar insulin. Sauran bincike na farko sun nuna cewa shan kayan hadin da ke dauke da berberine, policeosanol, jan yisti shinkafa, folic acid, coenzyme Q10, da astaxanthin na inganta hawan jini da zuban jini a cikin mutanen da ke fama da ciwo na rayuwa.
• Ofara kitse a cikin hanta a cikin mutanen da ke shan kaɗan ko kuma ba giya ba (cutar hanta mai haɗari ko NAFLD). Binciken farko ya nuna cewa berberine yana rage kitse a cikin jini da alamomin cutar hanta ga mutanen da ke fama da ciwon sukari da NAFLD. Sauran bincike na farko sun nuna cewa berberine na iya rage ƙiba a cikin hanta, alamomin ciwon hanta, da nauyi a cikin mutanen da ke da wannan yanayin. Berberine kamar tana aiki kamar kuma pioglitazone.
• Kiba. Binciken farko ya nuna cewa shan berberine na iya rage nauyi a cikin masu kiba da kusan fam 5.
• Cutar gudawa da aka samu ta hanyar maganin radiation. Wasu bincike na farko sun nuna cewa shan berberine a yayin maganin radiation zai iya rage rauni na hanji daga radiation a cikin marasa lafiya da ake kula da su don cutar kansa.
• Ofarƙashin ƙwayar nama wanda ya haifar da maganin radiation. Wasu bincike na farko sun nuna cewa shan berberine a yayin aikin fida na iya rage raunin huhu daga radiation cikin marasa lafiya da ake kula da su don cutar kansa.
• Levelsananan matakan platelets a cikin jini (thrombocytopenia). Gwanon jini yana da mahimmanci ga daskarewar jini. Bincike na farko ya nuna cewa shan berberine ko dai shi kadai ko tare da prednisolone, na iya kara yawan platelets na jini a cikin mutanen da ke da karancin kirinjin jini.
• Ciwon ido da cutar ta Chlamydia trachomatis (trachoma) ta haifar. Akwai wasu shaidu da ke nuna cewa digon ido dauke da sinadarin berberine na iya zama da amfani wajen magance cutar trachoma, sanadin makanta a kasashe masu tasowa.
• Wani nau'in cututtukan hanji mai kumburi (ulcerative colitis). Bincike na farko ya nuna cewa shan berberine ba ze inganta alamun a cikin mutanen da ke fama da cutar ulcerative colitis waɗanda ke shan maganin mesalamine.
• Sauran yanayi.

Ana buƙatar ƙarin shaida don kimanta tasirin berberine don waɗannan amfani.

Berberine na iya haifar da bugun zuciya mai ƙarfi. Wannan na iya taimakawa mutane da wasu yanayin zuciya. Berberine na iya taimakawa wajen daidaita yadda jiki ke amfani da sukari a cikin jini. Wannan na iya taimaka wa masu fama da ciwon sukari. Hakanan yana iya kashe ƙwayoyin cuta da rage kumburi.

Lokacin shan ta bakin: Berberine shine MALAM LAFIYA don mafi yawan manya don amfani na ɗan gajeren lokaci. Hanyoyi masu illa sun hada da gudawa, maƙarƙashiya, gas, ɓacin rai, da ciwon kai.

Lokacin amfani da fata: Berberine shine MALAM LAFIYA ga mafi yawan manya idan aka yi amfani da su na ɗan gajeren lokaci.

Kariya & Gargaɗi na Musamman:

Ciki da shan nono: Yana da KIMA INSAFE shan berberine da baki idan kuna ciki. Masu bincike sunyi imanin cewa berberine na iya haye mahaifa kuma yana iya haifar da lahani ga ɗan tayi. Kernicterus, wani nau'in lalacewar ƙwaƙwalwa, ya ɓullo a cikin jarirai sabbin haihuwa waɗanda ke fuskantar berberine.

Shima KIMA INSAFE shan berberine idan kuna shan nono. Ana iya canza Berberine zuwa ga jariri ta madarar nono, kuma yana iya haifar da cutarwa.

Yara: Yana da KIMA INSAFE don bada berberine ga jarirai. Zai iya haifar da kernicterus, wani nau'in nau'in lalacewar ƙwaƙwalwar da ke faruwa a cikin jarirai sabbin yara waɗanda ke da tsananin cutar jaundice. Jaundice yana yin launin ruwan fata ne sakamakon yawan bilirubin a cikin jini. Bilirubin wani sinadari ne da ake samarwa idan tsoffin kwayoyin halitta ja suka ruguje. Yawanci hanta ce ke cire shi. Berberine na iya hana hanta cire bilirubin cikin sauri. Babu isasshen ingantaccen bayani don sanin idan berberine yana da lafiya a cikin manyan yara.

Ciwon suga: Berberine na iya rage suga a cikin jini. A ka'idar, berberine na iya haifar da sukarin jini ya zama ƙasa sosai idan masu ciwon sukari waɗanda ke kula da sukarin jinin su da insulin ko magunguna suka sha. Yi amfani da hankali a cikin mutanen da ke da ciwon sukari.

Babban matakan bilirubin a cikin jini a cikin jarirai: Bilirubin wani sinadari ne wanda ake samar dashi lokacinda tsoffin kwayoyin jini ke narkewa. Yawanci hanta ce ke cire shi. Berberine na iya hana hanta cire bilirubin cikin sauri. Wannan na iya haifar da matsalar kwakwalwa, musamman a jarirai masu yawan bilirubin a cikin jini. Guji amfani.

Pressureananan hawan jini: Berberine na iya rage hawan jini. A ka'idar, berberine na iya ƙara haɗarin hawan jini ya zama ƙasa da mutane a cikin waɗanda suka riga sun kamu da cutar hawan jini. Yi amfani da hankali.

Manjo

Kada ku ɗauki wannan haɗin.

Cyclosporine (Neoral, Sandimmune)

Jiki yana rushe cyclosporine don kawar da shi. Berberine na iya rage saurin da jiki ke rushe cyclosporine kuma yana iya haɓaka cikin jiki kuma yana iya haifar da sakamako masu illa.

Matsakaici

Yi hankali da wannan haɗin.

Dextromethorphan (Robitussin DM, wasu)

Jiki yana lalata dextromethorphan don kawar dashi. Berberine na iya ragewa yadda sauri jiki ke farfasa shi kuma yana iya haɓaka sakamako da illa na dextromethorphan.

Distance Watsa-Losartan (Cozaar)

Hanta tana kunna losartan don yin aiki. Berberine na iya rage yadda jiki ke kunna shi da sauri, kuma yana iya rage tasirin sa.

Magunguna sun canza ta hanta (Cytochrome P450 2C9 (CYP2C9) substrates)

Wasu magunguna ana canza su ta hanta. Berberine na iya ragewa yadda hanta ke hanzarta wargaje waɗannan magungunan kuma ya ƙara tasirin su da illolinsu.

Wasu magunguna da hanta ta canza sun hada da celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), da S-warfarin (Coumadin).

Magunguna sun canza ta hanta (Cytochrome P450 2D6 (CYP2D6) substrates)

Wasu magunguna ana canza su ta hanta. Berberine na iya ragewa yadda hanta ke hanzarta wargaje waɗannan magungunan kuma ya ƙara tasirin su da illolinsu. Wasu magunguna da hanta ta canza sun hada da amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetil ), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), da sauransu.

Magunguna sun canza ta hanta (Cytochrome P450 3A4 (CYP3A4)

Wasu magunguna ana canza su ta hanta. Berberine na iya ragewa yadda hanta ke hanzarta wargaje waɗannan magungunan kuma ya ƙara tasirin su da illolinsu. Wasu magunguna da hanta ta canza sun haɗa da cyclosporin (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), da sauran su.

Magunguna don ciwon sukari (Magungunan cututtukan siga)

Berberine na iya rage sukarin jini. Ana amfani da magungunan ciwon suga don rage sukarin jini. Shan berberine tare da magungunan ciwon sikari na iya haifar da sikarin jininka ya yi ƙasa ƙwarai. Kula da yawan jinin ka sosai. Za a iya canza yawan adadin magungunan cutar sikari.

Wasu magungunan da ake amfani da su don ciwon suga sun haɗa da glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), da sauransu.

Magunguna don hawan jini (Magungunan antihypertensive)

Berberine na iya rage hawan jini a cikin wasu mutane. Shan berberine tare da magungunan da ake amfani dasu don saukar da hawan jini zai iya haifar da hawan jininka yayi ƙasa.

Wasu magunguna don hawan jini sun haɗa da captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), da sauransu da yawa .

Magunguna waɗanda ke jinkirta daskarewar jini (Magungunan Anticoagulant / Antiplatelet)

Berberine na iya rage daskarewar jini. Shan berberine tare da magunguna wanda shima jinkirin daskarewa na iya kara damar rauni da zub da jini.

Wasu magunguna da ke rage daskarewar jini sun hada da aspirin, cilostazol (Pletal), clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), da sauransu.

Metformin (Glucophage)

Berberine na iya kara adadin metformin a jiki. Wannan na iya ƙara tasirinsa da kuma tasirinsa. Wannan ma'amala kamar yana faruwa yayin ɗaukar berberine awanni 2 kafin metformin. Shan berberine da metformin a lokaci guda baya bayyana don kara yawan metformin a jiki.

Midazolam (Ayar)

Jiki yana rushe midazolam don kawar dashi. Berberine na iya ragewa yadda sauri jiki ke farfasa shi kuma yana iya haɓaka sakamako da illa na midazolam.

Pentobarbital (Nembutal)

Pentobarbital magani ne wanda kan iya haifar da bacci. Berberine na iya haifar da bacci da bacci. Shan berberine tare da pentobarbital na iya haifar da yawan bacci.

Magungunan kwantar da hankali (CNS depressants)

Berberine na iya haifar da bacci da bacci. Ana kiran magungunan da ke haifar da bacci. Shan berberine tare da magungunan kwantar da hankali na iya haifar da yawan bacci.

Wasu magungunan kwantar da hankali sun hada da benzodiazepines, pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), da sauransu.

Tacrolimus (Shirya)

Tacrolimus magani ne mai kariya. Ana cire shi daga jiki ta hanta. Berberine na iya ragewa da sauri jiki ya cire shi kuma wannan na iya haɓaka sakamako da tasirin tasirin tacrolimus.

Ganye da kari waɗanda zasu iya rage hawan jini

Berberine na iya rage hawan jini. Amfani da shi tare da sauran ganyayyaki da kari waɗanda ke da wannan tasirin na iya ƙara haɗarin saukar da hawan jini sosai a cikin wasu mutane. Wasu daga cikin wadannan kayayyakin sun hada da andrographis, casein peptides, cat's claw, coenzyme Q-10, man kifi, L-arginine, lycium, stinging nettle, theanine, da sauransu.

Ganye da kari waɗanda zasu iya rage sukarin jini

Berberine na iya rage sukarin jini. Amfani da shi tare da sauran ganyayyaki da kari waɗanda ke da tasiri iri ɗaya na iya haifar da sukarin jini ya ragu sosai a cikin wasu mutane. Wasu daga cikin wadannan kayayyakin sun hada da alpha-lipoic acid, melon meya, chromium, ta shedan, fenugreek, tafarnuwa, guar gum, dokin kirjin iri, Panax ginseng, psyllium, Siberian ginseng, da sauransu.

Ganye da kari wadanda zasu iya rage daskarewar jini

Berberine na iya rage daskarewar jini. Shan berberine tare da wasu ganyayyaki wanda na iya rage daskarewar jini na iya kara damar bruising da zubar jini. Wadannan ganyayyaki sun hada da Angelica, clove, danshen, tafarnuwa, ginger, ginkgo, Panax ginseng, da sauransu.

Ganye da kari tare da kayan haɓaka

Berberine na iya haifar da bacci ko bacci. Amfani da shi tare da sauran ganyayyaki da kari waɗanda ke da tasiri iri ɗaya na iya sa ku yin bacci mai yawa. Wasu daga cikin wadannan ganyayyaki da kari sun hada da calamus, California poppy, catnip, hops, Jamaica dogwood, kava, L-tryptophan, melatonin, sage, SAMe, St. John’s wort, sassafras, skullcap, da sauransu.

Magungunan rigakafi

Abubuwan kariya daga kwayoyin cuta suna dauke da kwayoyin cuta wadanda ake ganin suna da amfani ga lafiya. Berberine na iya kashe wasu ƙwayoyin cuta. Idan aka haɗu tare, berberine na iya rage yadda ingantattun kayan kari suke aiki.

Babu sanannun hulɗa da abinci.

MAGABATA

DA BAKI:

• Ga ciwon suga: An dauki 0.9-1.5 gram na berberine a cikin kashi biyu kowace rana tsawon watanni 2-4.
• Don yawan matakan cholesterol ko sauran mai (lipids) a cikin jini (hyperlipidemia): An dauki gram 0.6-1.5 na berberine a cikin kashi biyu kowace rana tsawon watanni 6 zuwa 24. Kayan hadawa wadanda suka hada da MG 500 na berberine, 10 mg na policeosanol, da 200 mg na red yeast rice, tare da sauran sinadarai, ana shan su kowace rana har zuwa watanni 12.
• Don hawan jini: An dauki gram 0.9 na berberine a kullum tsawon watanni 2.
• Don cutar rashin kwayar cutar da ke haifar da kara girman ƙwai da ƙwai (polycystic ovary syndrome ko PCOS): An dauki gram 1.5 na berberine a kullun tsawon watanni 3-6.

SHAFIN FATA:

• Don ciwon kwari: Gel mai dauke da MG 5 na berberine a kowane gram anyi amfani dashi sau hudu a rana tsawon kwana 5.

Alcaloïde de Berbérine, Berberina, Berbérine, Berberine Alkaloid, Berberine Complex, Berberine Sulfate, Sulfate de Berbérine, Umbellatine.

Don ƙarin koyo game da yadda aka rubuta wannan labarin, da fatan za a duba Magunguna na Compwararren Bayanan Bayanai hanya.

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