Mawallafi: William Ramirez
Ranar Halitta: 16 Satumba 2021
Sabuntawa: 21 Yuni 2024
Anonim
Cannabidiol (CBD) and Health | Pharmacology
Video: Cannabidiol (CBD) and Health | Pharmacology

Wadatacce

Cannabidiol sinadarai ne a cikin tsiron wiwi na wiwi, wanda aka fi sani da marijuana ko hemp. Fiye da sunadarai 80, da aka sani da suna cannabinoids, an gano su a cikin tsiren Cannabis sativa. Yayinda delta-9-tetrahydrocannabinol (THC) shine babban sinadarin aiki a cikin marijuana, ana samun cannabidiol daga hemp, wanda ya ƙunshi ƙananan ƙananan THC kawai.

Wucewar Dokar Gona ta 2018 ta halatta a sayar da kayan kwalliya da kayan kwalliya a cikin Amurka Amma wannan ba yana nufin cewa duk samfuran cannabidiol da aka samo daga hemp halal ne ba. Tun lokacin da aka yi nazarin cannabidiol a matsayin sabon magani, ba za a iya haɗa shi da doka ba cikin abinci ko abincin abincin. Hakanan, cannabidiol ba za a iya haɗa shi cikin kayayyakin da aka tallata tare da iƙirarin warkewa ba. Cannabidiol za a iya haɗa shi cikin kayayyakin "kwaskwarima" kuma kawai idan ya ƙunshi ƙasa da 0.3% THC. Amma har yanzu akwai samfuran da aka lakafta su azaman kayan abincin abincin akan kasuwa waɗanda ke ɗauke da cannabidiol. Adadin cannabidiol da ke cikin waɗannan samfuran ba koyaushe ana ba da rahoton daidai a kan samfurin samfurin ba.

Cannabidiol an fi amfani dashi don rikicewar cuta (epilepsy). Hakanan ana amfani dashi don damuwa, zafi, cututtukan tsoka da ake kira dystonia, cututtukan Parkinson, cutar Crohn, da sauran yanayi, amma babu kyakkyawar shaidar kimiyya don tallafawa waɗannan amfani.

Magunguna na Compwararren Bayanan Bayanai ƙimar tasiri bisa ga shaidar kimiyya bisa ga mizani mai zuwa: Inganci, Mai yuwuwa Mai Yiwuwa, Yiwuwar Tasiri, Yiwuwar Mara Inganci, Mai yiwuwa Mara Inganci, Mara Inganci, da suarancin Shaida don Rate.

Effectivenessimar tasiri don CANNABIDIOL (CBD) sune kamar haka:


Da alama tasiri ga ...

  • Ciwon cuta (farfadiya). Wani takamaiman samfurin cannabidiol (Epidiolex, GW Pharmaceuticals) an nuna don rage kamuwa da cuta a cikin manya da yara tare da yanayi daban-daban waɗanda ke da alaƙa da haɗuwa. Wannan samfurin magani ne na likitanci don magance cututtukan da cutar ta Dravet, Lennox-Gastaut ta ciwo, ko ƙwayar cuta ta ƙwayar cuta. Hakanan an nuna shi don rage kamuwa da cuta a cikin mutanen da ke fama da cutar Sturge-Weber, cututtukan cututtukan zazzaɓi da ke da alaƙa da cututtukan zazzaɓi (FIRES), da takamaiman cututtukan kwayar halitta waɗanda ke haifar da cututtukan kwakwalwa. Amma ba a yarda da shi ba don magance waɗannan nau'ikan nau'ikan kamawa. Ana ɗaukar wannan samfurin a haɗe tare da magungunan rigakafi na yau da kullun. Wasu samfuran cannabidiol da aka yi a cikin dakin gwaje-gwaje kuma ana nazarin su don farfadiya. Amma bincike yana iyakance, kuma babu ɗayan waɗannan samfuran da aka yarda da su azaman magunguna.

Evidencearancin shaida don kimanta inganci don ...

  • Wani nau'in cututtukan hanji mai kumburi (cutar Crohn). Binciken farko ya nuna cewa shan cannabidiol baya rage ayyukan cuta ga manya da cutar Crohn.
  • Ciwon suga. Bincike na farko ya nuna cewa shan cannabidiol ba ya inganta manya masu kula da glucose na jini tare da ciwon sukari na 2.
  • Rikicin motsi wanda aka alama da nakasar tsoka mara izini (dystonia). Babu tabbas idan cannabidiol yana da amfani ga dystonia.
  • Yanayin gado wanda aka yiwa alama ta nakasasun karatu (mai saurin lalacewa- X ciwo). Binciken farko ya nuna cewa yin amfani da gel na cannabidiol na iya rage damuwa da haɓaka halayyar yara da ke fama da cutar ta X.
  • Halin da dasawa ke afkawa cikin jiki (cututtukan-da-mai-karbar bakunci ko GVHD). Cututtukan da suke dauke da daskararren cuta shine rikitarwa wanda zai iya faruwa bayan dashen daskarewa da jijiya. Binciken farko ya gano cewa shan cannabidiol a kowace rana yana farawa kwanaki 7 kafin daskarewar kashi da ci gaba na tsawon kwanaki 30 bayan dasawar na iya tsawaita lokacin da mutum zai dauka don bunkasa GVHD.
  • Cutar ƙwaƙwalwar da aka gada wacce ke shafar motsi, motsin rai, da tunani (cutar Huntington). Binciken farko ya nuna cewa shan cannabidiol kowace rana baya inganta alamun cutar Huntington.
  • Mahara sclerosis (MS). Binciken farko ya nuna cewa yin amfani da maganin cannabidiol a ƙarƙashin harshe na iya inganta ciwo da ƙuntata tsoka a cikin mutane tare da MS.
  • Saukewa daga heroin, morphine, da sauran magungunan opioid. Binciken farko ya nuna cewa shan cannabidiol na tsawon kwanaki 3 na iya rage sha’awa da damuwa a cikin mutanen da ke fama da rikicewar amfani da tabar heroin.
  • Cutar Parkinson. Bincike na farko ya nuna cewa cannabidiol na iya rage damuwa da alamun cututtukan kwakwalwa a cikin mutanen da ke da cutar Parkinson.
  • Schizophrenia. Binciken farko ya nuna cewa shan cannabidiol yana inganta alamomin da jin daɗin mutanen da ke fama da cutar rashin lafiya.
  • Barin shan taba. Binciken farko ya nuna cewa shaƙar cannabidiol tare da inhaler na mako ɗaya na iya rage adadin sigarin da masu shan sigari ke sha.
  • Nau'in damuwa da ke nuna tsoro a cikin wasu ko duk saitunan zamantakewar (rikicewar tashin hankali). Binciken farko ya nuna cewa cannabidiol na iya haɓaka damuwa ga mutanen da ke da wannan cuta. Amma ba a bayyane yake ba idan yana taimakawa rage tashin hankali yayin magana a gaban jama'a.
  • Wani rukuni na yanayi mai raɗaɗi wanda ya shafi haɗin muƙamuƙin da tsoka (rikice-rikicen lokaci ko TMD). Binciken farko ya nuna cewa shafa mai mai dauke da cannabidiol ga fata na iya rage zafi ga mutanen da ke tare da TMD.
  • Lalacewar jijiyoyi a hannaye da kafafu (neuropathy na gefe).
  • Cutar rashin lafiya.
  • Rashin bacci.
  • Sauran yanayi.
Ana buƙatar ƙarin shaida don kimanta tasirin cannabidiol don waɗannan amfani.

Cannabidiol yana da tasiri akan kwakwalwa. Ainihin dalilin wadannan tasirin bai bayyana ba. Koyaya, cannabidiol kamar yana hana rugujewar wani sunadarai a cikin kwakwalwa wanda ke shafar ciwo, yanayi, da aikin tunani. Tsayar da lalacewar wannan sinadarin da haɓaka matakansa a cikin jini kamar yana rage alamun bayyanar cututtuka da ke haɗuwa da yanayi kamar schizophrenia. Hakanan Cannabidiol na iya toshe wasu daga tasirin tasirin psychota-9-tetrahydrocannabinol (THC). Hakanan, cannabidiol kamar yana rage zafi da damuwa.

Lokacin shan ta bakin: Cannabidiol shine MALAM LAFIYA lokacin da aka ɗauke ta baki ko aka fesa ta ƙarƙashin harshen yadda ya dace. Cannabidiol a cikin allurai har zuwa 300 MG kowace rana ana ɗauke da baki lafiya har zuwa watanni 6. An ɗauki mafi yawan allurai na 1200-1500 MG kowace rana ta bakin lafiya har zuwa makonni 4. Kayan magani na cannabidiol (Epidiolex) an yarda da shi don ɗaukar baki a cikin allurai har zuwa 25 mg / kg kowace rana. Cannabidiol sprays da ake amfani da su a ƙarƙashin harshe an yi amfani dasu a cikin allurai na 2.5 MG har zuwa makonni 2.

Wasu sakamako masu illa na cannabidiol sun hada da bushewar baki, ƙarancin jini, ƙoshin haske, da bacci. Hakanan an bayar da rahoton alamun cutar hanta ga wasu marasa lafiya, amma wannan ba shi da yawa.

Lokacin amfani da fata: Babu isasshen ingantaccen bayani don sanin ko cannabidiol yana da lafiya ko kuma menene tasirin illa na iya zama.

Kariya & Gargaɗi na Musamman:

Ciki da shan nono: Cannabidiol shine YIWU KA KIYAYE don amfani idan kun kasance masu ciki ko ciyar da nono. Za a iya gurɓata kayayyakin Cannabidiol tare da wasu sinadaran da za su iya zama lahani ga ɗan tayi ko jariri. Kasance a gefen aminci ka guji amfani.

Yara: Kayan maganin maganin cannabidiol (Epidiolex) shine MALAM LAFIYA lokacin shan ta baki cikin allurai har zuwa 25 mg / kg kowace rana. An yarda da wannan samfurin don amfani da wasu yara 1an shekara 1 zuwa sama.

Ciwon Hanta: Mutanen da ke da cutar hanta na iya buƙatar yin amfani da ƙananan maganin cannabidiol idan aka kwatanta da marasa lafiya.

Cutar Parkinson: Wasu bincike na farko sun nuna cewa shan allurai masu yawa na cannabidiol na iya haifar da motsin jiki da rawar jiki cikin wasu mutane da ke fama da cutar Parkinson.

Matsakaici
Yi hankali da wannan haɗin.
Brivaracetam (Briviact)
Jikin Brivaracetam ya canza kuma ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe brivaracetam.Wannan na iya kara matakan brivaracetam a jiki.
Carbamazepine (Tegretol)
Jikin Carbamazepine ya canza kuma ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke farfasa carbamazepine. Wannan na iya kara yawan sinadarin carbamazepine a cikin jiki da kuma kara tasirinsa.
Clobazam (Onfi)
Clobazam ya canza kuma hanta ta karye shi. Cannabidiol na iya rage yadda hanta ke saurin karye clobazam. Wannan na iya haɓaka sakamako da illa na clobazam.
Eslicarbazepine (Aptiom)
Jikin Eslicarbazepine ya canza kuma ya karye ta jiki. Cannabidiol na iya rage yadda sauri jiki ke rushe eslicarbazepine. Wannan na iya kara matakan eslicarbazepine a cikin jiki da karamin adadi.
Everolimus (Zostress)
Everolimus ya canza kuma jiki ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe everolimus. Wannan na iya kara yawan matakan everolimus a jiki.
Lithium
Shan mafi yawan allurai na cannabidiol na iya ƙara matakan lithium. Wannan na iya kara haɗarin guba na lithium.
Magunguna sun canza ta hanta (Cytochrome P450 1A1 (CYP1A1) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da chlorzoxazone (Lorzone) da theophylline (Theo-Dur, wasu).
Magunguna da hanta suka canza (Cytochrome P450 1A2 (CYP1A2) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya haɓaka sakamako da illa na wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, wasu), verapamil (Calan, Isoptin, wasu), da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 1B1 (CYP1B1) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da theophylline (Theo-Dur, wasu), omeprazole (Prilosec, Omesec), clozapine (Clozaril, FazaClo), progesterone (Prometrium, wasu), lansoprazole (Prevacid), flutamide (Eulexin), oxaliplatin (Eloxatin) ), erlotinib (Tarceva), da maganin kafeyin.
Magunguna sun canza ta hanta (Cytochrome P450 2A6 (CYP2A6) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya haɓaka sakamako da illa na wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da nicotine, chlormethiazole (Heminevrin), coumarin, methoxyflurane (Penthrox), halothane (Fluothane), valproic acid (Depacon), disulfiram (Antabuse), da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 2B6 (CYP2B6) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da ketamine (Ketalar), phenobarbital, orphenadrine (Norflex), secobarbital (Seconal), da dexamethasone (Decadron).
Magunguna da hanta suka canza (Cytochrome P450 2C19 (CYP2C19) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da proton pump inhibitors wadanda suka hada da omeprazole (Prilosec), lansoprazole (Prevacid), da pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 2C8 (CYP2C8) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.
Wasu magunguna da hanta ta canza sun hada da amiodarone (Cordarone), carbamazepine (Tegretol), chloroquine (Aralen), diclofenac (Voltaren), paclitaxel (Taxol), repaglinide (Prandin) da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 2C9 (CYP2C9) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magungunan da hanta ta canza sun hada da nonsteroidal anti-inflammatory anti-inflammatory drugs (NSAIDs) kamar diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), piroxicam (Feldene), da celecoxib (Celebrex); amitriptyline (Elavil); warfarin (Coumadin); glipizide (Glucotrol); losartan (Cozaar); da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 2D6 (CYP2D6) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetil ), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), da sauransu.
Magunguna da hanta suka canza (Cytochrome P450 3A4 (CYP3A4) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya haɓaka sakamako da illa na wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da alprazolam (Xanax), amlodipine (Norvasc), clarithromycin (Biaxin), cyclosporine (Sandimmune), erythromycin, lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), trixof) (Halcion), verapamil (Calan, Isoptin) da sauransu da yawa.
Magunguna sun canza ta hanta (Cytochrome P450 3A5 (CYP3A5) substrates)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, amfani da cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya haɓaka sakamako da illa na wasu magunguna. Kafin amfani da cannabidiol, yi magana da mai ba ka kiwon lafiya idan ka sha magunguna wadanda hanta ke canza su.

Wasu magunguna da hanta ta canza sun hada da testosterone, progesterone (Endometrin, Prometrium), nifedipine (Adalat CC, Procardia XL), cyclosporine (Sandimmune), da sauransu.
Magunguna sun canza ta hanta (Magungunan Glucuronidated)
Wasu magunguna ana canza su ta hanta. Cannabidiol na iya rage yadda hanta ke saurin wargaza wasu magunguna. Shan cannabidiol tare da wasu magunguna waɗanda hanta ke lalata na iya ƙara tasiri da tasirin tasirin waɗannan magunguna.
Wasu daga cikin wadannan magungunan da hanta ta canza sun hada da acetaminophen (Tylenol, wasu) da oxazepam (Serax), haloperidol (Haldol), lamotrigine (Lamictal), morphine (MS Contin, Roxanol), zidovudine (AZT, Retrovir), da sauransu.
Magunguna waɗanda ke rage raunin wasu magunguna ta hanta (Masu hanawa na Cytochrome P450 2C19 (CYP2C19))
Cannabidiol ya lalace ta hanta. Wasu magunguna na iya rage yadda hanta ke hanzarta saukar da cannabidiol. Shan cannabidiol tare da waɗannan magunguna na iya ƙara tasiri da illa masu illa na cannabidiol.
Wasu magunguna waɗanda zasu iya rage raunin cannabidiol a cikin hanta sun haɗa da cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), da sauransu.
Magunguna waɗanda ke rage raunin wasu magunguna a cikin hanta (Masu hanawa na Cytochrome P450 3A4 (CYP3A4))
Cannabidiol ya lalace ta hanta. Wasu magunguna na iya rage yadda hanta ke hanzarta saukar da cannabidiol. Shan cannabidiol tare da waɗannan magunguna na iya ƙara tasiri da illa masu illa na cannabidiol.
Wasu magunguna da zasu iya rage yadda hanta ke saurin lalacewa cannabidiol sun hada da amiodarone (Cordarone), clarithromycin (Biaxin), diltiazem (Cardizem), erythromycin (E-mycin, Erythrocin), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Fortovase , Invirase), da sauransu.
Magunguna waɗanda ke ƙara ragargaza wasu magunguna ta hanta (masu ba da magani na Cytochrome P450 3A4 (CYP3A4))
Cannabidiol ya lalace ta hanta. Wasu magunguna na iya ƙaruwa da sauri hanta ta lalace cannabidiol. Shan cannabidiol tare da waɗannan magunguna na iya rage tasirin cannabidiol.
Wasu daga cikin wadannan magunguna sun hada da carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), da sauransu.
Magunguna waɗanda ke ƙara ragargaza wasu magunguna ta hanta (masu shigar da cuta na Cytochrome P450 2C19 (CYP2C19))
Cannabidiol ya lalace ta hanta. Wasu magunguna na iya ƙaruwa da sauri hanta ta lalace cannabidiol. Shan cannabidiol tare da waɗannan magunguna na iya rage tasirin cannabidiol.
Wasu magunguna waɗanda zasu iya ƙara lalatawar cannabidiol a cikin hanta sun haɗa da carbamazepine (Tegretol), prednisone (Deltasone), da rifampin (Rifadin, Rimactane).
Methadone (Dolophine)
Hanta ne ya farfasa methadone Cannabidiol na iya rage yadda hanta ke saurin warke methadone. Shan cannabidiol tare da methadone na iya haɓaka sakamako da illa na methadone.
Rufinamide (Banzel)
Rufinamide ya canza kuma jiki ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe rufinamide. Wannan na iya ƙara matakan rufinamide a cikin jiki da ɗan kaɗan.
Magungunan kwantar da hankali (CNS depressants)
Cannabidiol na iya haifar da bacci da bacci. Ana kiran magungunan da ke haifar da bacci. Shan cannabidiol tare da magungunan kwantar da hankali na iya haifar da yawan bacci.

Wasu magungunan kwantar da hankali sun hada da benzodiazepines, pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan), da sauransu.
Sirolimus (Rapamune)
Sirolimus ya canza kuma jiki ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe sirolimus. Wannan na iya kara yawan sirolimus a jiki.
Stiripentol (Diacomit)
Stiripentol ya canza kuma jiki ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe stiripentol. Wannan na iya kara matakan stiripentol a cikin jiki kuma ya kara illolinta.
Tacrolimus (Shirya)
Tacrolimus ya canza kuma jiki ya karye shi. Cannabidiol na iya rage yadda sauri jiki ke rushe tacrolimus. Wannan na iya kara matakan tacrolimus a jiki.
Topiramate foda (Tompamax)
Topiramate foda ya canza kuma ya rushe ta jiki. Cannabidiol na iya rage yadda sauri jiki ke rushe topiramate. Wannan na iya ƙara matakan Topiramate a cikin jiki da ɗan kaɗan.
Matsayi
Valproic acid na iya haifar da raunin hanta. Shan cannabidiol tare da valproic acid na iya kara damar cutar hanta. Cannabidiol da / ko valproic acid na iya buƙatar dakatarwa, ko kuma ana buƙatar rage adadin.
Warfarin
Cannabidiol na iya ƙara matakan warfarin, wanda zai iya ƙara haɗarin zub da jini. Cannabidiol da / ko warfarin na iya buƙatar dakatarwa, ko kuma ana buƙatar rage adadin.
Zonisamide
Zonisamide ya canza kuma jiki ya rushe shi. Cannabidiol na iya rage yadda sauri jiki ke rushe zonisamide. Wannan na iya kara yawan matakan zonisamide a jiki ta karamin adadin.
Ganye da kari tare da kayan haɓaka
Cannabidiol na iya haifar da bacci ko bacci. Amfani da shi tare da sauran ganyayyaki da kari waɗanda ke da tasiri iri ɗaya na iya haifar da yawan bacci. Wasu daga cikin wadannan ganyayyaki da kari sun hada da calamus, California poppy, catnip, hops, Jamaica dogwood, kava, L-tryptophan, melatonin, sage, SAMe, St. John’s wort, sassafras, skullcap, da sauransu.
Alkahol (Ethanol)
Shan cannabidiol tare da barasa yana kara adadin cannabidiol wanda jiki ke sha. Wannan na iya haɓaka sakamako da illa na cannabidiol.
Fats da abinci mai dauke da mai
Shan cannabidiol tare da abinci mai dauke da mai ko kuma a kalla yana dauke da wani kitse, yana kara adadin cannabidiol da jiki ke sha. Wannan na iya haɓaka sakamako da illa na cannabidiol.
Madara
Shan cannabidiol tare da madara yana kara adadin cannabidiol wanda jiki ke sha. Wannan na iya haɓaka sakamako da illa na cannabidiol.
An yi nazarin ƙwayoyi masu zuwa a cikin binciken kimiyya:

MAGABATA

DA BAKI:
  • Don farfadiya: An yi amfani da samfurin maganin cannabidiol (Epidiolex). Amfani da shawarar farawa don cutar Lennox-Gastaut da Ciwan Dravet shine 2.5 mg / kg sau biyu a rana (5 mg / kg / day). Bayan mako guda ana iya ƙara nauyin zuwa 5 mg / kg sau biyu a rana (10 mg / kg / day). Idan mutum bai amsa wannan maganin ba, matsakaicin shawarar shine 10 mg / kg sau biyu a rana (20 mg / kg / day). Abun da aka fara farawa don hadadden ƙwayar cuta na ƙwayar cuta shine 2.5 MG / kg sau biyu a rana (5 mg / kg / day). Ana iya haɓaka wannan a tsaka-tsakin mako idan ya cancanta, har zuwa kusan 12.5 mg / kg sau biyu a rana (25 mg / kg / day). Babu wata shaidar kimiyya mai ƙarfi da ta nuna cewa samfuran cannabidiol da ba a yin rajista ba suna da amfani ga farfadiya.
YARA

DA BAKI:
  • Don farfadiya: An yi amfani da samfurin maganin cannabidiol (Epidiolex). Amfani da shawarar farawa don cutar Lennox-Gastaut da Ciwan Dravet shine 2.5 mg / kg sau biyu a rana (5 mg / kg / day). Bayan mako guda ana iya ƙara nauyin zuwa 5 mg / kg sau biyu a rana (10 mg / kg / day). Idan mutum bai amsa wannan maganin ba, matsakaicin shawarar shine 10 mg / kg sau biyu a rana (20 mg / kg / day). Abubuwan da aka fara farawa don hadadden ƙwayar cuta na ƙwayar cuta shine 2.5 MG / kg sau biyu a rana (5 mg / kg / day). Ana iya haɓaka wannan a tsaka-tsakin mako idan ya cancanta, har zuwa kusan 12.5 mg / kg sau biyu a rana (25 mg / kg / day). Babu wata hujja mai ƙarfi ta kimiyya da ke nuna cewa samfuran cannabidiol ba sa rajista suna da amfani ga farfadiya.
2 - [(1R, 6R) -3-Methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl] -5-pentylbenzene-1,3-diol, CBD.

Don ƙarin koyo game da yadda aka rubuta wannan labarin, da fatan za a duba Magunguna na Compwararren Bayanan Bayanai hanya.


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