Mawallafi: Virginia Floyd
Ranar Halitta: 13 Agusta 2021
Sabuntawa: 1 Afrilu 2025
Anonim
NIACINAMIDE - IS IT WORTH THE HYPE? DERMATOLOGISTS WEIGH IN
Video: NIACINAMIDE - IS IT WORTH THE HYPE? DERMATOLOGISTS WEIGH IN

Wadatacce

Akwai nau'i biyu na bitamin B3. Wani nau'i shine niacin, ɗayan kuma niacinamide. Ana samun Niacinamide a cikin abinci da yawa da suka hada da yisti, nama, kifi, madara, ƙwai, koren kayan lambu, wake, da hatsin hatsi. Niacinamide ana samun shi a yawancin ƙwayoyin bitamin B masu yawa tare da sauran bitamin B. Ana kuma iya samar da niacinamide a cikin jiki daga niacin abincin da ake ci.

Kada ku dame niacinamide da niacin, NADH, nicotinamide riboside, inositol nicotinate, ko tryptophan. Duba jerin daban don waɗannan batutuwa.

Niacinamide ana shan shi ta baki don hana rashi bitamin B3 da yanayin da suka dace kamar su pellagra. Hakanan ana ɗauka ta baki don ƙuraje, ciwon sukari, kansar baki, osteoarthritis, da sauran yanayi da yawa. Koyaya, babu kyakkyawar shaidar kimiyya don tallafawa waɗannan amfani.

Ana kuma amfani da Niacinamide ga fatar fatar kuraje, eczema, da sauran yanayin fata. Har ila yau, babu wata kyakkyawar shaida don tallafawa waɗannan amfani.

Magunguna na Compwararren Bayanan Bayanai ƙimar tasiri bisa ga shaidar kimiyya bisa ga mizani mai zuwa: Inganci, Mai yuwuwa Mai Yiwuwa, Yiwuwar Tasiri, Yiwuwar Mara Inganci, Mai yiwuwa Mara Inganci, Mara Inganci, da suarancin Shaida don Rate.

Effectivenessimar tasiri don NIACINAMIDE sune kamar haka:


Da alama tasiri ga ...

  • Wata cuta sanadiyyar karancin niacin (pellagra). Niacinamide ta amince da Hukumar Abinci da Magunguna ta Amurka (FDA) don waɗannan amfani. Niacinamide wani lokacin ana fifita shi akan niacin saboda baya haifarda "flushing," (redness, itching and tingling), wani illolin maganin niacin.

Yiwuwar tasiri ga ...

  • Kuraje. Binciken farko ya nuna cewa shan allunan da ke dauke da niacinamide da sauran sinadarai na tsawon makwanni 8 yana inganta bayyanar fata ga mutanen da ke fama da feshin fata. Sauran bincike sun nuna cewa sanya cream wanda ke dauke da niacinamide yana inganta bayyanar fata ga mutanen da ke da kuraje.
  • Ciwon suga. Wasu bincike sun nuna cewa shan niacinamide na iya taimakawa hana asarar samarwar insulin ga yara da manya da ke cikin hatsarin kamuwa da ciwon sukari na 1. Hakanan yana iya hana asarar samarwar insulin da rage adadin insulin da yara ke buƙata da yara da aka gano kwanan nan da ciwon sukari na nau'in 1. Koyaya, niacinamide ba ze hana ci gaban kamuwa da ciwon sukari na 1 a cikin yara masu haɗari ba. A cikin mutanen da ke da ciwon sukari na 2, niacinamide kamar yana taimakawa kare haɓakar insulin da inganta kula da sukarin jini.
  • Babban matakan phosphate a cikin jini (hyperphosphatemia). Yawan jini na sinadarin phosphate na iya haifar da rage aikin koda. A cikin mutanen da ke fama da gazawar koda waɗanda ke kan hemodialysis kuma suna da matakan jini mai yawa, shan niacinamide da alama zai taimaka wajen rage matakan phosphate lokacin da aka ɗauka tare da ko ba tare da sinadarin phosphate ba.
  • Ciwon kai da wuya. Bincike ya nuna cewa shan niacinamide yayin karbar radiotherapy da wani nau'in magani da ake kira carbogen na iya taimakawa wajen sarrafa ciwace ciwace da kuma kara rayuwa a cikin wasu mutane masu cutar kansa ta makoshi. Shan niacinamide yayin karbar radiotherapy da carbogen da alama yana amfanar mutanen da ke da cutar kansa ta maƙogwaro wanda suma rashin jini ne. Hakanan yana da alama taimaka wa mutanen da ke da kumburi wanda aka cire oxygen.
  • Ciwon kansa. Shan niacinamide da alama zai taimaka wajan hana sabuwar cutar sankara ta fata ko kuma tabo na musamman (actinic keratosis) daga samuwar mutane da tarihin kansar fata ko actinic keratosis.
  • Osteoarthritis. Shan niacinamide da alama yana inganta sassaucin haɗin gwiwa da rage ciwo da kumburi a cikin mutanen da ke fama da cutar sanyin ƙashi. Hakanan, wasu mutanen da ke fama da cutar sanyin ƙashi wanda ke shan niacinamide na iya buƙatar ɗaukar ƙananan magungunan ciwo.

Zai yuwu bashi da tasiri ga ...

  • Ciwon kwakwalwa. Binciken farko da aka gudanar ya nuna cewa yin jinyar mutane da cututtukan ƙwaƙwalwar da aka cire ta hanyar tiyata tare da niacinamide, radiotherapy, da carbogen ba ya inganta rayuwa idan aka kwatanta da radiotherapy ko radiotherapy da carbogen.
  • Ciwon daji na mafitsara. Kula da mutanen da ke fama da cutar kansar mafitsara tare da niacinamide, radiotherapy, da carbogen bai bayyana yana rage ci gaban tumo ba ko inganta rayuwa idan aka kwatanta da radiotherapy ko radiotherapy da carbogen.

Evidencearancin shaida don kimanta inganci don ...

  • Ciwon ido wanda ke haifar da rashin hangen nesa a cikin tsofaffi (lalacewar cuta ta tsufa ko AMD). Binciken farko ya nuna cewa shan niacinamide, bitamin E, da lutein na tsawon shekara guda yana inganta yadda kwayar ido take aiki a cikin mutane masu fama da matsalar hangen nesa masu alaka da shekaru saboda lalacewar ido.
  • Fatar tsufa. Binciken farko ya nuna cewa shafa kirim mai dauke da niacinamide 5% a fuska yana inganta kumburin ciki, tsukewa, sanyin jiki, da kuma yin ja ga mata masu tsufar fata saboda lalacewar rana.
  • Cancanta (atopic dermatitis). Binciken farko ya nuna cewa shafa kirim mai dauke da niacinamide 2% na rage rashi ruwa da inganta ruwa, kuma yana rage jan jiki da sikila, a cikin mutane masu cutar eczema.
  • Rashin hankali-raunin rashin hankali (ADHD). Akwai hujjoji masu karo da juna game da amfanin niacinamide hade da wasu bitamin don maganin ADHD.
  • Redness na fata wanda ya haifar da rauni ko damuwa (erythema). Binciken da aka fara yi ya nuna cewa sanya cream wanda ke dauke da niacinamide yana rage launin fata, bushewa, da ƙaiƙayi sanadiyyar isotretinoin na maganin ƙuraje.
  • Ciwon koda na dogon lokaci (cututtukan koda kodayaushe ko CKD). Binciken da aka fara yi ya nuna cewa shan niacinamide ba zai taimaka wajen rage kaikayi ga mutanen da ke da cutar koda ba.
  • Hasken fata mai duhu akan fuska (melasma). Binciken farko ya nuna cewa shafa moisturizer mai dauke da 5% niacinamide ko 2% niacinamide tare da 2% tranexamic acid na tsawon makwanni 4-8 na taimaka wa fata mai haske a cikin mutane masu duhun fata.
  • Ciwon daji wanda ke farawa a cikin ƙwayoyin jini fari (ba Hodgkin lymphoma). Binciken farko ya nuna cewa shan niacinamide a matsayin wani bangare na jiyya tare da wani magani da ake kira vorinostat na iya taimaka wa mutanen da ke fama da cutar lymphoma su shiga gafara.
  • Yanayin fata wanda ke haifar da jan fuska (rosacea). Binciken farko ya nuna cewa shan allunan da ke dauke da niacinamide da sauran sinadarai na tsawon makwanni 8 na inganta bayyanar fata ga mutanen da ke da rosacea.
  • Taushi, fatar fata a fatar kai da fuska (seborrheic dermatitis). Binciken farko da aka gudanar ya nuna cewa shafa cream mai dauke da kashi 4 cikin dari na niacinamide na iya rage jan launi da fatar fata a cikin mutanen da ke da cutar seborrheic dermatitis.
  • Shaye-shaye.
  • Alzheimer cuta.
  • Amosanin gabbai.
  • Rage ƙwaƙwalwar ajiya da ƙwarewar tunani waɗanda ke faruwa daidai da shekaru.
  • Bacin rai.
  • Hawan jini.
  • Ciwon motsi.
  • Ciwon premenstrual (PMS).
  • Sauran yanayi.
Ana buƙatar ƙarin shaida don kimanta niacinamide don waɗannan amfani.

Ana amfani da Niacinamide daga niacin a jiki. Niacin yana canzawa zuwa niacinamide idan aka sha shi da yawa fiye da yadda jiki yake bukata. Niacinamide yana iya narkewa cikin ruwa kuma yana da nutsuwa yayin shan ta bakin.

Ana buƙatar Niacinamide don aikin da ya dace na ƙwayoyi da sukari a cikin jiki da kuma kula da ƙwayoyin rai.

Ba kamar niacin ba, niacinamide ba shi da wani amfani mai amfani a kan mai kuma bai kamata a yi amfani da shi ba wajen magance yawan ƙwayoyin cuta ko kuma yawan mai a cikin jini. Lokacin shan ta bakin: Niacinamide shine LAFIYA LAFIYA ga mafi yawan manya lokacin da aka ɗauke su cikin adadin da aka ba da shawarar. Ba kamar niacin ba, niacinamide ba ya haifar da ruwa. Koyaya, niacinamide na iya haifar da ƙananan sakamako masu illa kamar rikicewar ciki, gas, jiri, kumburi, ƙaiƙayi, da sauran matsaloli. Don rage haɗarin waɗannan cututtukan, manya su guji shan niacinamide a cikin allurai fiye da 35 MG kowace rana.

Lokacin da aka sha allurai fiye da gram 3 a kowace rana na niacinamide, to illa mafi illa na iya faruwa. Wadannan sun hada da matsalolin hanta ko hawan jini.

Lokacin amfani da fata: Niacinamide shine MALAM LAFIYA. Kirkin Niacinamide na iya haifar da ƙananan ƙonawa, ƙaiƙayi, ko ja.

Kariya & Gargaɗi na Musamman:

Ciki da shan nono: Niacinamide shine LAFIYA LAFIYA ga mata masu ciki da masu shayarwa lokacin da aka sha cikin adadin da aka ba da shawarar. Matsakaicin shawarar da ake bayarwa na niacin ga mata masu juna biyu ko masu shayarwa shine MG 30 a kowace rana ga mata ‘yan kasa da shekaru 18, da 35 MG kowace rana ga mata sama da shekaru 18.

Yara: Niacinamide shine LAFIYA LAFIYA lokacin da aka ɗauke ta baki a cikin adadin shawarar don kowane rukunin shekaru. Amma yara yakamata su guji shan allurar niacinamide sama da iyakokin yau da kullun, waɗanda sune 10 MG ga yara yearsan shekaru 1-3, 15 MG ga yara 4an shekaru 4-8, 20 MG ga yara 9an shekaru 9-13, kuma 30 MG ga yara 14-18 shekara.

Allerji: Niacinamide na iya haifar da rashin lafiyar jiki mafi tsanani saboda suna haifar da histamine, sinadarin da ke da alaƙa da alamun rashin lafiyan, don saki.

Ciwon suga: Niacinamide na iya kara yawan suga a cikin jini. Mutanen da ke da ciwon sukari waɗanda suke shan niacinamide ya kamata su bincika suga da ke cikin jini da kyau.

Ciwon ciki: Niacinamide na iya haifar da cutar gallbladder.

Gout: Babban adadin niacinamide na iya haifar da gout.

Ciwan koda: Shan niacinamide da alama na kara kasadar masu saurin karancin jini a cikin mutanen da ke fama da matsalar koda wanda ke yin wankin koda.

Ciwon Hanta: Niacinamide na iya kara cutar hanta. Kada kayi amfani dashi idan kana da cutar hanta.

Cutar ciki ko hanjin ciki: Niacinamide na iya haifar da ulcers. Kada kayi amfani dashi idan kana da ulce.

Tiyata: Niacinamide na iya tsoma baki tare da kula da sukarin jini yayin da bayan tiyata. Dakatar da shan niacinamide aƙalla makonni 2 kafin a shirya maka aikin tiyata.

Matsakaici
Yi hankali da wannan haɗin.
Carbamazepine (Tegretol)
Jiki yana lalata Carbamazepine (Tegretol). Akwai wata damuwa cewa niacinamide na iya rage saurin da jiki ke lalata carbamazepine (Tegretol). Amma babu isasshen bayani don sanin idan wannan yana da mahimmanci.
Magungunan da zasu iya cutar da hanta (Hepatotoxic drugs)
Niacinamide na iya cutar da hanta, musamman idan aka yi amfani da shi a manyan allurai. Shan niacinamide tare da magani wanda kuma zai iya cutar da hanta na iya kara haɗarin cutar hanta. Kada ku sha niacinamide idan kuna shan magani wanda zai iya cutar da hanta.

Wasu magungunan da zasu iya cutar da hanta sun hada da acetaminophen (Tylenol da sauransu), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporano) erythromycin (Erythrocin, Ilosone, wasu), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), da sauransu da yawa.
Magunguna waɗanda ke jinkirta daskarewar jini (Magungunan Anticoagulant / Antiplatelet)
Niacinamide na iya jinkirta daskarewar jini. Shan niacinamide tare da magunguna wadanda suma jinkirin daskarewa na iya kara damar samun rauni da zubar jini.

Wasu magunguna da ke rage daskarewar jini sun hada da asfirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), da sauransu.
Primidone (Mysoline)
Jiki ya farfasa Primidone (Mysoline). Akwai wata damuwa cewa niacinamide na iya rage saurin da jiki ke lalata primidone (Mysoline). Amma babu isasshen bayani don sanin idan wannan yana da mahimmanci.
Ganye da kari waɗanda zasu iya cutar da hanta
Niacinamide na iya haifar da lalacewar hanta, musamman idan aka yi amfani da shi a cikin manyan allurai. Shan niacinamide tare da wasu ganyayyaki ko kari wanda zai iya cutar da hanta na iya ƙara wannan haɗarin. Wasu daga cikin wadannan kayayyakin sun hada da instenedione, borage leaf, chaparral, comfrey, dehydroepiandrosterone (DHEA), germander, kava, pennyroyal oil, ja yisti, da sauransu.
Ganye da kari wadanda zasu iya rage daskarewar jini
Niacinamide na iya jinkirta daskarewar jini. Yin amfani da niacinamide tare da sauran ganyayyaki da kari wanda kuma jinkirin daskarewar jini na iya ƙara haɗarin zubar jini a cikin wasu mutane. Wasu sauran ganyayyaki irin wannan sun hada da Angelica, clove, danshen, tafarnuwa, ginger, Panax ginseng, da sauransu.
Babu sanannun hulɗa da abinci.
An yi nazarin ƙwayoyi masu zuwa a cikin binciken kimiyya:

MAGABATA

DA BAKI:
  • Janar: Wasu samfuran ƙarin kayan abinci ba zasu lissafa niacinamide daban akan alamar ba. Madadin haka, ana iya lissafa shi a ƙarƙashin niacin. Ana auna Niacin a cikin kwatankwacin niacin (NE). Yawan kashi 1 na niacinamide yayi daidai da 1 mg NE. Tallafin abinci na yau da kullum (RDAs) na niacinamide a cikin manya sune 16 mg NE ga maza, 14 mg NE ga mata, 18 mg NE ga mata masu juna biyu, da 17 mg NE na mata masu shayarwa.
  • Domin kuraje: Allunan da ke ɗauke da MG 750 na niacinamide, 25 mg of zinc, 1.5 mg na jan ƙarfe, da 500 mcg na folic acid (Nicomide) sau ɗaya ko sau biyu ana amfani da su. Hakanan, an dauki allunan 1-4 dauke da niacinamide, azelaic acid, zinc, bitamin B6, jan ƙarfe, da folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) a kowace rana.
  • Don alamun rashin ƙarancin bitamin B3 kamar su pellagra: 300-500 MG a kowace rana na niacinamide ana ba su kashi biyu.
  • Ga ciwon suga: Niacinamide gram 1.2 / m2 (yanayin farfajiyar jiki) ko 25-50 mg / kg ana amfani dashi yau da kullun don jinkirin ci gaba da ciwon sukari na nau'in 1. Hakanan, ana amfani da giram 0.5 na niacinamide sau uku a kowace rana don rage ci gaban ciwon sukari na nau'in 2.
  • Don manyan matakan phosphate a cikin jini (hyperphosphatemia): Niacinamide daga MG 500 har zuwa gram 1.75 kowace rana a rarrabuwa ana amfani dashi tsawon makonni 8-12.
  • Don ciwon daji na maƙogwaro: Ana ba da 60 mg / kg na niacinamide awanni 1-1.5 kafin shakar ƙwayoyin cuta (2% carbon dioxide da 98% oxygen) kafin da yayin aikin rediyo.
  • Don ciwon daji na fata banda melanoma: 500 mg na niacinamide sau daya ko biyu a kullum tsawon watanni 4-12.
  • Don magance cutar sanyin kashi: Gram 3 na niacinamide kowace rana a raba allurai tsawon sati 12.
AKAN FATA:
  • Kuraje: Gel mai dauke da sinadarin niacinamide na kashi 4% sau biyu a rana.
YARA

  • Janar: Tallafin abinci na yau da kullun (RDAs) don niacinamide a cikin yara sune 2 MG na jarirai watanni 0-6, 4 MG NE ga jarirai watanni 7-12, 6 MG NE na yara 1-3 shekaru, 8 mg NE na yara 4 zuwa shekaru, 12 mg NE na yara 9 shekaru, 16 mg NE na maza 14-18, da 14 mg NE na mata 14-18 shekaru.
  • Domin kuraje: A cikin yara akalla shekaru 12, ana shan allunan 1-4 da ke ɗauke da niacinamide, azelaic acid, zinc, bitamin B6, jan ƙarfe, da folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) kowace rana.
  • Don pellagra: 100-300 MG na niacinamide ana bayarwa kowace rana cikin kashi biyu.
  • Ga ciwon sukari na 1: Gram 1.2 / m2 (yanayin farfajiyar jiki) ko 25-50 mg / kg na niacinamide ana amfani dashi yau da kullun don jinkirin ci gaba ko hana ciwon sukari irin na 1.
3-Pyridine Carboxamide, 3-Pyridinecarboxamide, Amide de l'Acide Nicotinique, B Complex Vitamin, Complexe de Vitamines B, Niacinamida, Nicamid, Nicosedine, Nicotinamide, Nicotinic Acid Amide, Nicotylamidum, Pyridine-3-carboxamide, Vitamin B3, Vitamina B , Vitamine B3.

Don ƙarin koyo game da yadda aka rubuta wannan labarin, da fatan za a duba Magunguna na Compwararren Bayanan Bayanai hanya.


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