Cobicistat

Wadatacce

• Kafin shan cobicistat,
• Cobicistat na iya haifar da sakamako masu illa. Faɗa wa likitanka idan wannan alamar ta yi tsanani ko ba ta tafi ba:
• Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, kira likitan ku nan da nan:

Ana amfani da Cobicistat don kara yawan atazanavir (Reyataz, a cikin Evotaz) a cikin manya da yara masu aƙalla fam 77 (35 kg) ko darunavir (Prezista, a Prezcobix) a cikin manya da yara masu aƙalla fam 88 (40 kg) a jini lokacin da ake amfani da waɗannan magunguna don magance ƙwayar ƙwayar ƙwayar ɗan adam (HIV). Cobicistat yana cikin ajin magungunan da ake kira cytochrome P450 3A (CYP3A). Yana aiki ta hanyar ƙara yawan atazanavir ko darunavir a cikin jiki don su sami babban sakamako.

Cobicistat ya zo a matsayin kwamfutar hannu don ɗauka ta bakin. Yawanci ana ɗauka tare da abinci sau ɗaya a rana tare da atazanavir ko darunavir. Coauki cobicistat tare da atazanavir ko darunavir a kusan lokaci ɗaya kowace rana. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Coauki cobicistat daidai kamar yadda aka umurce ku. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Yana da mahimmanci koyaushe a ɗauki cobicistat a lokaci ɗaya kamar atazanavir ko darunavir.

Tambayi likitan ko likitan ku don kwafin bayanan masu sana'anta ga mai haƙuri.

Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan cobicistat,

• gaya wa likitan ku da likitan ku idan kun kasance masu rashin lafiyan cobicistat, duk wasu magunguna, ko kuma duk wani sinadaran da ke cikin allunan cobicistat. Tambayi likitan ku kan jerin kayan hadin.
• gaya wa likitanka idan kuna shan ɗayan magunguna masu zuwa: alfuzosin (Uroxatral); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol); cisapride (Propulsid) (babu a Amurka); colchicine (cryira, Mitigare, a cikin Col-Probenecid); dronedarone (Multaq); ergot magunguna kamar dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, a Cafergot, a Migergot), da methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Altoprev); lurasidone (Latuda); midazolam (Aya) ta baki; sashin jiki; phenytoin (Dilantin, Phenytek); pimozide (Orap); ranolazine (Ranexa); rifampin (Rimactane, Rifadin, a cikin Rifamate, a cikin Rifater); sildenafil (kawai alamar Revatio da ake amfani da ita don cutar huhu); simvastatin (Flolipid, Zocor); St. John’s wort; ko triazolam (Halcion). Idan kana shan atazanavir tare da cobicistat, gaya wa likitanka idan kana shan drospirenone da ethinyl estradiol (wasu magungunan hana daukar ciki kamar su Beyaz, Safyral, Yasmin, Yaz, wasu); indinavir (Crixivan), irinotecan (Camptosar), ko nevirapine (Viramune). Kila likitanku zai gaya muku kar ku ɗauki cobicistat idan kuna shan ɗayan waɗannan magunguna.
• gaya wa likitanka da likitan kantin ku wasu irin magunguna da magunguna marasa magani, bitamin, kayan abinci mai gina jiki, da kayan ganyen da kuke sha ko shirin dauka. Tabbatar da ambaci kowane daga cikin masu zuwa: masu hana yaduwar jini ('masu kara jini') kamar apixaban (Eliquis), betrixaban (Bevyxxa), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban (Xarelto), da warfarin (Coumadin, Jantoven) ; magungunan antiplatelet kamar su clopidogrel (Plavix) da ticagrelor (Brilinta); atorvastatin (Lipitor, a cikin Caduet); benzodiazepines kamar su diazepam (Valium), estazolam, midazolam da aka ba su ta hanyar jijiyoyin jini (cikin jijiya), da zolpidem (Ambien, Edluar, Intermezzo); masu hana beta kamar su carvedilol (Coreg), metoprolol (Lopressor), da timolol; boceprevir (Victrelis) (ba a cikin Amurka); bosentan (Tracleer); buprenorphine (Belbuca, Butrans, Probuphine); buprenorphine da naloxone (Suboxone, Zubsolv); buspirone; masu toshe hanyar tashar calcium kamar su amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Tiazac, wasu), felodipine, nifedipine (Adalat, Afeditab, Procardia), da verapamil (Calan, Verelan, wasu); clarithromycin (Biaxin, a cikin PrevPac); corticosteroids kamar beclomethasone (Beconase AQ), budesonide (Rhinocort Aqua), ciclesonide (Omnaris), dexamethasone (Decadron), fluticasone (Flonase, Flovent), methylprednisolone (Medrol), momentasone (Flonase),da triamcinolone (Nasacort AQ); dasatinib (Sprycel); efavirenz (Sustiva, a cikin Atripla); erythromycin (E.E.S, Erytab, wasu); etravirine (Intelence); fentanyl (Abstral, Actiq, Fentora, wasu); itraconazole (Onmel, Sporanox); ketoconazole; magunguna don damuwa kamar amitriptyline, desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Brisdelle, Paxil, Pexeva), da trazodone; magunguna don bugun zuciya mara kyau kamar amiodarone (Cordarone, Nexterone, Pacerone), digoxin (Lanoxin), disspyramide (Norpace), flecainide, mexiletine, propafenone (Rythmol), da quinidine (a Nuedexta); magunguna don kamuwa kamar su clonazepam (Klonopin), eslicarbazepine (Aptiom), da oxcarbazepine (Trileptal); magungunan da ke danne tsarin garkuwar jiki kamar su cyclosporine (Gengraf, Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune), da tacrolimus (Astagraf, Envarsus XR, Prograf); lopinavir (a cikin Kaletra); maraviroc (Selzentry); methadone (Dolophine, Methadose); nilotinib (Tasigna); magungunan hana daukar ciki (kwayoyin hana haihuwa); labaran rana; wasu magungunan phosphodiesterase (PDE5) kamar avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), da vardenafil (Levitra); quetiapine (Seroquel); rifabutin (Mycobutin); risperidone (Risperdal); ritonavir (Norvir, a cikin Kaletra); rivaroxaban foda (Xarelto); rosuvastatin; salmeterol (Serevent, a cikin Advair); simeprevir (Olysio); telaprevir (Incivek) (ba a cikin Amurka); telithromycin (Ketek); tenofovir (Viread, a Atripla, Complera, Truvada, wasu), thioridazine; tramadol (Conzip, Ultram, a cikin Ultracet); vinblastine; vincristine (Marqibo Kit); da voriconazole (Vfend). Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa. Sauran magunguna da yawa na iya yin ma'amala da cobicistat don haka tabbatar da gaya wa likitanka game da duk magungunan da kuke sha, har ma waɗanda ba su bayyana a wannan jeri ba.
• idan kuna shan cobicistat tare da atazanavir kuma kuna shan antacids (Maalox, Mylanta, Tums, wasu), ɗauki su awanni 2 kafin ko awa 2 bayan cobicistat da atazanavir.
• idan kuna shan cobicistat tare da atazanavir kuma kuna kuma shan magani don rashin narkewar ciki, ƙwannafi, ko ulcers (H₂ masu toshewa) kamar cimetidine, famotidine (Pepcid, in Duexis), nizatidine (Axid), ko ranitidine (Zantac), ɗauki su a lokaci guda ko aƙalla awanni 10 bayan shan H₂ mai toshewa
• idan kuna shan cobicistat tare da atazanavir kuma kuna kuma shan magani don rashin narkewar ciki, ƙwannafi, ko ulcers (proton pump inhibitors) kamar esomeprazole (Nexium, a Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, a Zegerid), pantoprazole (Protonix), ko rabeprazole (AcipHex) suna ɗaukar su aƙalla awanni 12 bayan shan maganin proton pump.
• gaya wa likitanka idan kana da ko ka taba yin koda ko cutar hanta.
• gaya wa likitanka idan kana da juna biyu, ka shirya yin ciki, ko kuma kana shayarwa. Idan kun kasance ciki yayin shan cobicistat, kira likitan ku. Bai kamata ku shayar da nono ba idan kun kamu da kwayar HIV ko kuma idan kuna shan cobicistat.

Sai dai idan likitanku ya gaya muku in ba haka ba, ci gaba da abincinku na yau da kullun.

Idan adadin ku na gaba ya kasance a cikin 12 hours ko fiye, ɗauki kashi da aka rasa da zarar kun tuna da shi. Koyaya, idan za'a ɗauki kashi na gaba a ƙasa da awanni 12, tsallake sashin da aka ɓace kuma ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Cobicistat na iya haifar da sakamako masu illa. Faɗa wa likitanka idan wannan alamar ta yi tsanani ko ba ta tafi ba:

• tashin zuciya

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, kira likitan ku nan da nan:

• rawaya fata ko idanu
• kurji
• rage fitsari

Cobicistat na iya haifar da wasu sakamako masu illa. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.

Idan kun fuskanci mummunan sakamako, ku ko likitanku na iya aika rahoto ga shirin Abinci da Magunguna na Hukumar Kula da Abinci da Magunguna (FDA) na kan layi (http://www.fda.gov/Safety/MedWatch) ko ta waya ( 1-800-332-1088).

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye shi a zafin jiki na ɗaki kuma nesa da yawan zafin rana da danshi (ba cikin gidan wanka ba).

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani. Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Idan ya wuce gona da iri, kira layin taimakon guba a 1-800-222-1222. Hakanan ana samun bayanai akan layi akan https://www.poisonhelp.org/help. Idan wanda aka azabtar ya faɗi, ya kamu, fama da numfashi, ko ba za a iya farkawa ba, nan da nan kira sabis na gaggawa a 911.

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanku zai ba da umarnin wasu gwaje-gwajen gwaje-gwaje a gabanin da yayin jiyya don bincika martanin jikinku ga cobicistat.

Rike wadatar magunguna a hannu. Kada ka yi jira har sai ka gama shan magani don sake cika takardar sayan magani.

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

• Tybost^®

• Evotaz^® (dauke da Atazanavir, Cobicistat)
• Prezcobix^® (dauke da Cobicistat, Darunavir)