Spironolactone (Aldactone)

Wadatacce

• Menene don
• Yadda ake dauka
• 1. Hawan jini mai mahimmanci
• 2. Rashin Ciwon Zuciya
• 3. Ciwan hanta
• 4. Ciwon mara
• 5. Ciwon ciki
• 6. Hypokalemia / hypomagnesaemia
• 7. Magungunan rigakafi na Primary Hyperaldosteronism
• 8. Ciwan mara hawan jini
• Hanyar aiwatarwa
• Matsalar da ka iya haifar
• Contraindications

Spironolactone, wanda aka sani da kasuwanci kamar Aldactone, yana aiki ne azaman diuretic, yana ƙara kawar da ruwa ta cikin fitsari, kuma a matsayin maganin hawan jini, kuma ana iya amfani dashi wajen maganin cutar hawan jini, kumburi da ke da alaƙa da matsaloli a cikin aikin zuciya ko cututtuka a cikin hanta da koda, hypokalemia ko a cikin maganin hyperaldosteronism, misali.

A wasu lokuta, ana iya ba da wannan maganin don maganin ƙuraje kuma don hana zubewar gashi, duk da haka waɗannan aikace-aikacen ba sa cikin manyan alamomi na spironolactone, kuma ba a ambata su a cikin saka kunshin ba.

Ana iya siyan Spironolactone a cikin shagunan magani, kan farashin kusan 14 zuwa 45 reais, ya danganta da ko mutum ya zaɓi alama ko janar, yana buƙatar gabatar da takardar sayan magani.

Menene don

Ana nuna Spironolactone don:

• Hawan jini mai mahimmanci;
• Edema da ke faruwa sakamakon matsalolin zuciya, koda ko hanta;
• Idiopathic edema;
• Taimakon taimako a cikin mummunan hauhawar jini;
• Hypokalemia lokacin da ake ɗaukar wasu matakan bai dace ba ko bai dace ba;
• Rigakafin hypokalemia da hypomagnesaemia a cikin mutanen da ke shan diuretics;
• Ganewar asali da magani na hyperaldosteronism.

Koyi game da wasu nau'ikan diuretics kuma koya yadda suke aiki.

Yadda ake dauka

Sashi ya dogara da matsalar da za a bi da shi:

1. Hawan jini mai mahimmanci

Halin da aka saba amfani da shi shine 50 MG / rana zuwa 100 mg / day, wanda a cikin tsayayyar yanayi ko mai tsanani za a iya ƙaruwa sannu a hankali, a tsakanin makonni biyu, har zuwa 200 MG / rana. Ya kamata a ci gaba da jiyya na mafi karancin makonni biyu don tabbatar da isasshen martani ga magani. Ya kamata a daidaita kashi kamar yadda ake buƙata.

2. Rashin Ciwon Zuciya

Abubuwan da aka fara farawa yau da kullun shine 100 MG a cikin guda ɗaya ko raba kashi, wanda zai iya bambanta tsakanin 25 MG da 200 MG kowace rana. Ya kamata a tantance gwargwadon yawan kiyayewa ga kowane mutum.

3. Ciwan hanta

Idan yawan sinadarin sodium / urinary potassium ya fi 1 girma, yawan shan kashi 100 mg / rana. Idan wannan rabo bai kai 1 ba, gwargwadon shawarar shine 200 mg / day zuwa 400 mg / day. Ya kamata a tantance gwargwadon yawan kiyayewa ga kowane mutum.

4. Ciwon mara

Abun da aka saba yi a cikin manya shine 100 MG / rana zuwa 200 MG / rana.

5. Ciwon ciki

Halin da aka saba amfani da shi shine 100 MG kowace rana don manya kuma kusan 3.3 MG da kilogiram na nauyin da ake gudanarwa a cikin kashi kashi-kashi. Ya kamata a daidaita sashi bisa ga amsa da jurewar kowane mutum.

6. Hypokalemia / hypomagnesaemia

Ana bada shawarar yin amfani da 25 mg / day zuwa 100 mg / day a cikin maganin hypopotassemia da / ko hypomagnesemia da masu cutar diure ke jawowa, lokacin da sinadarin potassium da / ko sinadarin magnesium bai wadatar ba.

7. Magungunan rigakafi na Primary Hyperaldosteronism

Lokacin da aka gano asalin cututtukan hyperaldosteronism ta hanyar ƙarin tabbatattun gwaje-gwaje, ana iya gudanar da spironolactone a cikin allurai na 100 MG zuwa 400 MG a shirye-shiryen tiyata.

8. Ciwan mara hawan jini

Ya kamata a yi amfani dashi azaman magani na taimako kuma idan akwai ɓataccen ɓataccen aldosterone, hypokalemia da alkalosis na rayuwa. Sashin farawa shine 100 MG / rana, wanda za'a iya ƙaruwa, lokacin da ya cancanta, a tsakanin makonni biyu, har zuwa 400 MG / rana.

Hanyar aiwatarwa

Spironolactone wani takamaiman antagonist ne na aldosterone, wanda ke aiki akasari akan gidan masarrafan dogaro da sododi da potassium ion, wanda ke cikin matattarar tubule ta koda, wanda ke haifar da ƙara yawan sinadarin sodium da kawar da ruwa da kuma ƙaruwar riƙe potassium.

Matsalar da ka iya haifar

Wasu daga cikin cututtukan cututtukan spironolactone na iya haɗawa da neoplasm mara kyau, leukopenia, thrombocytopenia, rikicewar lantarki, canje-canje a cikin libido, rikicewa, rashin hankali, cututtukan ciki da tashin zuciya, aikin hanta mara kyau, cutar Steve-Johnson, cututtukan epidermal necrolysis, saurin kwayoyi, gashi asara, hauhawar jini, kaikayi, amya, ciwon mara a kafa, rashin saurin koda, ciwon nono, rikicewar al'ada, gynecomastia da malaise.

Contraindications

Spironolactone bai kamata mutane suyi amfani dashi ga abubuwanda aka tsara na maganin ba, mutanen da suke fama da matsalar rashin koda, nakasa aikin koda, cutar anuria, cutar Addison, hyperkalaemia ko kuma wadanda suke amfani da magani mai suna eplerenone.