Bugawa Bincike kan Endometriosis: Abin da kuke Bukatar Ku sani

Wadatacce

• Bugawa kan maganin endometriosis
• Sabon maganin baka
• Zaɓuɓɓukan tiyata da gwajin gwaji mai zuwa
• Bugawa akan bincikar cututtukan endometriosis
• Researcharin binciken endometriosis a sararin sama
• Kwayoyin halitta masu maimaitawa
• Gene far
• Takeaway

Bayani

Endometriosis yana shafar kimanin mata. Idan kuna zaune tare da endometriosis, zaku iya ɗaukar matakai don gudanar da alamun cutar. Babu magani har yanzu, amma masana kimiyya suna aiki tuƙuru don nazarin endometriosis da yadda za a iya magance shi da kyau.

A cikin 'yan shekarun nan, ƙungiyar bincike mai girma ta bincika abubuwan da ke haifar da endometriosis, hanyoyin da ba su da haɗari da ake amfani da su don gano yanayin, da zaɓuɓɓukan magani na dogon lokaci. Karanta don koyo game da ci gaban zamani.

Bugawa kan maganin endometriosis

Gudanar da ciwo shine babban maƙasudin mafi yawan jiyya don endometriosis. Dukansu maganin likita da magungunan ciwon kan-kan-kan da magungunan maganin hormone galibi ana ba da shawarar su. Yin aikin tiyata shima zaɓi ne na magani.

Sabon maganin baka

A lokacin bazara na 2018, Hukumar Abinci da Magunguna ta Amurka (FDA) ta amince da farkon antagonist mai sakin gonadotropin (GnRH) don taimaka wa mata masu fama da matsanancin ciwo mai tsanani daga endometriosis.

Elagolix shine. Yana aiki ta dakatar da samar da isrogen. Hormone estrogen yana taimakawa wajen haɓakar cututtukan endometrial da alamun rashin jin daɗi.

Yana da mahimmanci a lura cewa masu adawa da GnRH da gaske suna sanya jiki cikin jinin al'ada. Wannan yana nufin illa masu illa na iya haɗawa da asarar ƙashin kashi, walƙiya mai zafi, ko bushewar farji, da sauransu.

Zaɓuɓɓukan tiyata da gwajin gwaji mai zuwa

Gidauniyar Endometriosis ta Amurka ta ɗauki tiyatar cire laparoscopic a matsayin mizanin zinariya don aikin tiyata na yanayin. Manufar tiyatar ita ce cire cututtukan endometrial tare da kiyaye ƙoshin lafiya.

Yin aikin tiyata na iya cin nasara a rage cututtukan cututtukan endometriosis, bayanin kula a cikin mujallar lafiyar Mata. Zai yiwu ma, tare da izinin da aka riga aka sanar, don likita don yin aikin tiyata don magance endometriosis a matsayin ɓangare na hanya ɗaya don bincikar yanayin. Nazarin 2018 wanda ya kunshi fiye da mahalarta 4,000 ya gano cewa tiyatar cire laparoscopic shima yana da tasiri wajen magance ciwon mara da kuma alamun hanji na endometriosis.

Wani sabon gwaji na asibiti a cikin Netherlands na nufin yin tiyata har ma da inganci. Batu guda tare da hanyoyin tiyata na yanzu shine cewa idan ba a cire raunin endometriosis kwata-kwata, alamun cututtuka na iya dawowa. Lokacin da wannan ya faru, ana iya buƙatar maimaita aikin. Wani sabon gwaji na asibiti yana binciken amfani da hasken rana don taimakawa hana buƙatar maimaita tiyata.

Bugawa akan bincikar cututtukan endometriosis

Daga jarrabawar pelvic zuwa ultrasounds zuwa laparoscopic surgery, hanyoyin mafi inganci na bincikar cututtukan endometriosis suna da haɗari sosai. Yawancin likitoci na iya bincikar cututtukan endometriosis dangane da tarihin likita da gwajin jiki. Koyaya, tiyatar laparoscopic - wanda ya haɗa da saka ƙaramin kyamara don bincika ƙirar endometrial - har yanzu shine hanyar da aka fi so don ganewar asali.

Endometriosis na iya ɗaukar tsakanin tsakanin shekaru 7 zuwa 10 don tantancewa. Rashin gwaje-gwajen cututtukan marasa haɗari na ɗaya daga cikin dalilan da ke haifar da wannan dogon lokacin.

Hakan na iya canza wata rana. Kwanan nan, masana kimiyya tare da Cibiyar Nazarin Kiwon Lafiya ta Feinstein suka wallafa wani binciken da ke nuna gwaje-gwajen kan samfurin jinin haila na iya samar da wata hanya mai amfani, mara cutarwa ta bincikar cututtukan endometriosis.

Masu binciken sun gano cewa kwayoyin da ke jinin jinin mata masu dauke da cutar endometriosis suna da wasu halaye. Musamman, jinin haila ya ƙunshi ƙananan ƙwayoyin halitta masu kashe mahaifa. Hakanan ya kasance yana da ƙwayoyin ƙwayoyin cuta tare da raunin “rashin yanke hukunci,” tsarin da ke shirya mahaifa don ɗaukar ciki.

Ana buƙatar ƙarin bincike. Amma yana yiwuwa waɗannan alamomin wata rana zasu iya samar da hanya mai sauri da mara haɗari don tantance cututtukan endometriosis.

Researcharin binciken endometriosis a sararin sama

Bincike game da cututtukan endometriosis da magani yana kan gudana. Manyan biyu - kuma da ɗan ilimin kimiya - sun bayyana a ƙarshen 2018:

Kwayoyin halitta masu maimaitawa

A cikin wani bincike daga Magunguna na Arewa maso Yamma, masu bincike sun gano cewa ƙwayoyin halittar mutum (iPS) da ke haifar da ƙwayoyin cuta za a iya “sake fasalinsu” don canzawa zuwa cikin ƙoshin lafiya, maye gurbin ƙwayoyin mahaifa. Wannan yana nufin cewa za a iya maye gurbin ƙwayoyin mahaifa masu haifar da ciwo ko kumburi tare da lafiyayyun ƙwayoyin.

Waɗannan ƙwayoyin halitta an ƙirƙire su ne daga wadataccen sel na matan sel na iPS. Wannan yana nufin babu haɗarin ƙin yarda da gabobi, kamar yadda yake tare da wasu nau'ikan dashewa.

Ana buƙatar ƙarin bincike. Amma akwai yiwuwar maganin ƙwayoyin cuta wanda zai zama dogon lokaci maganin endometriosis.

Gene far

Har yanzu ba a san dalilin endometriosis ba. Wasu bincike sun nuna cewa danniyar takamaiman kwayoyin halitta na iya taka rawa.

Masana kimiyya a Jami'ar Yale sun wallafa wani binciken da suka gano cewa microRNA Let-7b - magabaciyar kwayar halittar da ke kula da nuna jinsi - ana danniya a cikin mata masu fama da cututtukan fata. Mafita? Gudanar da Let-7b ga mata na iya taimaka magance yanayin.

Ya zuwa yanzu, maganin kawai an nuna yana da tasiri a cikin beraye. Masu binciken sun ga babban ragi a cikin raunin endometrial bayan allurar beraye da Let-7b. Ana buƙatar ƙarin bincike kafin gwaji a cikin mutane.

Idan maganin jinsi ya tabbatar da tasiri a cikin mutane, yana iya zama hanyar da ba tiyata, mara cutarwa, da kuma hanyar da bazata iya magance endometriosis ba.

Takeaway

Duk da yake babu maganin endometriosis, yana da magani. Bincike kan yanayin, zaɓuɓɓukan magani, da gudanarwa suna kan gudana. Idan kana sha'awar ƙarin koyo, yi magana da likitanka. Za su iya amsa tambayoyinku kuma ba da shawarar albarkatu don neman ƙarin.