Myeloid na cutar sankarar bargo na yau da kullun: menene menene, haddasawa, alamu da magani

Wadatacce

• Menene alamun
• Matsaloli da ka iya haddasawa
• Menene dalilai masu haɗari
• Menene ganewar asali
• Yadda ake yin maganin
• 1. Magunguna
• 2. dasawar qashi
• 3. Chemotherapy
• 4. Maganin Interferon

Myeloid Leukemia na yau da kullun (CML) ba shi da wani nau'in nau'in cutar kansa wanda ba shi da gado wanda ke tasowa sakamakon canjin kwayoyin halittar jini, da ke haifar musu da saurin rabuwa fiye da na al'ada.

Za a iya gudanar da jiyya ta hanyar shan magani, dasashi na kashin baya, chemotherapy ko kuma ta hanyar hanyoyin nazarin halittu, ya danganta da tsananin matsalar ko kuma mutumin da za a kula da shi.

Samun damar warkarwa galibi suna da yawa, amma yana iya bambanta gwargwadon ci gaban cutar, da shekaru da kuma lafiyar lafiyar wanda ya kamu. Yawancin lokaci, magani tare da mafi kyawun ƙimar magani shine dashewar ƙashi, amma mutane da yawa bazai ma buƙatar zuwa wannan maganin ba.

Menene alamun

Alamomi da alamomin da zasu iya faruwa a cikin mutane masu fama da cutar sankarar Myeloid na yau da kullun sune:

• Zubar da jini akai-akai;
• Gajiya;
• Zazzaɓi;
• Rage nauyi ba tare da wani dalili ba;
• Rashin ci;
• Jin zafi a ƙasa da haƙarƙarin, a gefen hagu;
• Gwanin;
• Yawan gumi a dare.

Wannan cutar ba ta bayyana alamomi da alamomin da ke bayyane nan take a matakin farko kuma wannan ne ya sa ake iya rayuwa tare da wannan cutar na tsawon watanni ko ma shekaru ba tare da mutum ya ankara ba.

Matsaloli da ka iya haddasawa

Kwayoyin mutane suna dauke da nau'ikan chromosomes guda 23, wadanda suke dauke da DNA tare da kwayoyin halittar da ke shiga tsakani wajen kula da kwayoyin halitta a jiki. A cikin mutanen da ke fama da cutar sankara ta Myeloid Leukemia, a cikin ƙwayoyin jini, wani sashe na chromosome 9 yana canza wurare tare da chromosome 22, yana samar da ɗan gajeren chromosome 22, wanda ake kira chromosome na Philadelphia da chromosome mai tsayi sosai 9.

Wannan kwayar halittar Philadelphia din sai ta kirkiro wani sabon kwayar halittar, kuma kwayoyin halittar kwayoyin chromosome 9 da 22 sai su kirkiri wani sabon kwayar halitta mai suna BCR-ABL, wanda ya kunshi umarni da ke fadawa wannan sabon kwayar da ba ta dace ba don ta samar da wani sinadari mai yawa wanda ake kira tyrosine kinase. yana haifar da samuwar cutar kansa ta hanyar barin ƙwayoyin jini da yawa suyi girma ta yadda ba za a iya sarrafa su ba, tare da lalata kasusuwan ƙashi.

Menene dalilai masu haɗari

Abubuwan da zasu iya ƙara haɗarin kamuwa da cutar Myeloid Leukemia na yau da kullun sun tsufa, kasancewarsu maza kuma ana fuskantar fallasa su, kamar su maganin fida da ake amfani dashi don magance wasu nau'ikan cutar kansa.

Menene ganewar asali

Gabaɗaya, lokacin da ake zargin wannan cuta, ko lokacin da ko lokacin da wasu alamomin halayyar suka faru, ana yin bincike wanda ya ƙunshi gwajin jiki, kamar bincika alamomi masu muhimmanci da hawan jini, bugun ƙwayoyin lymph, ƙwaya da ciki, a hanya don gano yiwuwar rashin haɗari.

Bugu da kari, daidai ne kuma ga likita ya bada umarnin gwajin jini, biopsy wani kashin kashin samfurin, wanda yawanci ana daukarsa daga kashin hanji, da karin gwaje-gwaje na musamman, kamar su fulosol a cikin binciken hadewar wuri da kuma gwajin karfin sarkar polymerase, wanda yake nazari jini ko samfurin kasusuwa don kasancewar kwayar halittar Philadelphia ko kuma kwayar halittar BCR-ABL.

Yadda ake yin maganin

Manufar magance wannan cutar ita ce kawar da ƙwayoyin jini waɗanda ke ɗauke da kwayar halittar da ba ta dace ba, wanda ke haifar da samar da adadi mai yawa na ƙwayoyin jini mara kyau. Ga wasu mutane ba zai yiwu a kawar da dukkanin ƙwayoyin ƙwayoyin cuta ba, amma magani na iya taimakawa wajen yaƙar cutar.

1. Magunguna

Za a iya amfani da magungunan da ke toshe aikin na tyrosine kinase, kamar su Imatinib, Dasatinib, Nilotinib, Bosutinib ko Ponatinib, waɗanda yawanci magani ne na farko ga masu wannan cuta.

Illolin da wadannan magunguna zasu iya haifarwa sune kumburin fata, jiri, ciwon tsoka, kasala, gudawa da kuma tasirin fata.

2. dasawar qashi

Dasawar kasusuwan kasusuwa shine kawai hanyar magani wacce ke bada tabbaci na dawwamammen cutar Myeloid Leukemia. Koyaya, ana amfani da wannan hanyar ne kawai a cikin mutanen da basa karɓar wasu magunguna saboda wannan ƙirar tana gabatar da haɗari kuma yana iya haifar da rikitarwa mai tsanani.

3. Chemotherapy

Chemotherapy kuma magani ne wanda aka yi amfani dashi a cikin yanayin na Myeloid Leukemia na yau da kullun kuma sakamakon illa ya dogara da nau'in magani da aka yi amfani da shi a maganin. San nau'ikan nau'ikan cutar sankara da yadda ake yinta.

4. Maganin Interferon

Magungunan ilimin halitta suna amfani da tsarin garkuwar jiki don taimakawa yaƙi da cutar kansa ta amfani da furotin da ake kira interferon, wanda ke taimakawa wajen rage haɓakar ƙwayoyin tumo. Ana iya amfani da wannan fasahar a yanayin da sauran jiyya ba sa aiki ko kuma a cikin mutanen da ba za su iya shan wasu magunguna ba, kamar mata masu juna biyu, misali.

Abubuwan da suka fi dacewa a cikin wannan maganin sune gajiya, zazzaɓi, mura da alamun rashi.