Tambayoyi 9 Game da Waldenstrom Macroglobulinemia

Wadatacce

• 1. Shin Waldenstrom macroglobulinemia yana iya warkewa?
• 2. Shin Waldenstrom macroglobulinemia zai iya shiga gafara?
• 3. Ta yaya Waldenstrom macroglobulinemia ke da wuya?
• 4. Ta yaya Waldenstrom macroglobulinemia ke ci gaba?
• 5. Shin Waldenstrom macroglobulinemia yana gudana a cikin iyalai?
• 6. Me ke haifar da Waldenstrom macroglobulinemia?
• 7. Har yaushe zaku iya zama tare da Waldenstrom macroglobulinemia?
• 8. Shin Waldenstrom macroglobulinemia zai iya maye gurbinsa?
• 9. Yaya ake kula da Waldenstrom macroglobulinemia?
• Takeaway

Waldenstrom macroglobulinemia (WM) wani nau'i ne mai mahimmanci na lymphoma ba na Hodgkin ba wanda ke da alaƙa da yawan fitowar ƙwayoyin jini fari mara kyau.

Yana da sannu-sannu nau'in ciwan ƙwayar ƙwayar ƙwayar jini wanda ke shafar 3 cikin kowane mutum miliyan 1 a Amurka kowace shekara, a cewar Canungiyar Ciwon Sankaran Amurkawa.

Ana kiran WM wani lokaci kuma:

• Waldenstrom ta cuta
• kwayar cutar lymphoplasmacytic
• na farko macroglobulinemia

Idan an gano ku tare da WM, kuna iya samun tambayoyi da yawa game da cutar. Koyo gwargwadon iko game da ciwon daji da bincika hanyoyin zaɓin magani na iya taimaka muku jure yanayin.

Anan akwai amsoshin tambayoyi tara waɗanda zasu iya taimaka muku fahimtar WM.

1. Shin Waldenstrom macroglobulinemia yana iya warkewa?

WM a halin yanzu bashi da sanannen magani. Koyaya, ana samun magunguna iri-iri don taimaka maka gudanar da alamomin ka.

Hangen nesa ga mutanen da aka bincikar su da WM ya inganta tsawon shekaru. Masana kimiyya kuma suna binciken allurar rigakafi don taimakawa haɓaka ƙarfin garkuwar jiki don ƙin irin wannan ciwon daji da haɓaka sababbin zaɓuɓɓukan magani.

2. Shin Waldenstrom macroglobulinemia zai iya shiga gafara?

Akwai ƙaramar dama cewa WM na iya shiga cikin gafara, amma ba al'ada ba ce. Likitoci kawai sun ga cikakkiyar gafarar cutar a cikin mutane kalilan. Jiyya na yanzu baya hana sake dawowa.

Duk da yake babu bayanai da yawa game da yawan gafarar, karamin binciken daga 2016 ya gano cewa tare da WM ya shiga cikin cikakkiyar gafara bayan an bi da shi tare da "tsarin R-CHOP."

Tsarin R-CHOP ya haɗa da amfani da:

• rituximab
• saukarinna
• vincristine
• doxorubicin
• prednisone

Sauran mahalarta 31 sun sami gafarar sashi.

Yi magana da likitanka don ganin idan wannan magani, ko wani tsarin, ya dace maka.

3. Ta yaya Waldenstrom macroglobulinemia ke da wuya?

Likitoci suna bincikar mutane 1,000 zuwa 1,500 a Amurka tare da WM kowace shekara, a cewar toungiyar Ciwon Sankara ta Amurka. Nationalungiyar ofasa ta Rare Rarraba ta ɗauki shi a matsayin yanayi mai saurin gaske.

WM yakan shawo kan maza sau biyu kamar yadda yake yiwa mata. Cutar ba ta cika faruwa ba tsakanin baƙar fata kamar yadda ake yi tsakanin fararen fata.

4. Ta yaya Waldenstrom macroglobulinemia ke ci gaba?

WM yana neman cigaba sosai. Yana haifar da wuce haddi na wasu nau'ikan kwayoyin farin jini da ake kira B lymphocytes.

Waɗannan ƙwayoyin suna haifar da ƙarancin wani antibody da ake kira immunoglobulin M (IgM), wanda ke haifar da yanayin kaurin jini da ake kira hyperviscosity. Wannan yana da wahala ga gabobin ku da kayan aiki suyi aiki yadda yakamata.

Excessarancin ƙwayoyin lymphocytes na B na iya barin ƙaramin ɗaki a cikin ɓargo don lafiyayyun ƙwayoyin jini. Kuna iya kamuwa da karancin jini idan adadin ƙwayar jinin ku ya ragu sosai.

Rashin ƙwayoyin farin jini na yau da kullun na iya wahalar da jikin ku don yaƙar wasu nau'o'in ƙwayoyin cuta. Hakanan platelet dinka na iya zubewa, wanda zai iya haifar da zub da jini da zafin jiki.

Wasu mutane ba su da alamun bayyanar shekaru da yawa bayan ganewar asali.

Alamomin farko sun hada da kasala da karancin kuzari sakamakon karancin jini. Hakanan ƙila ka sami ƙwanƙwasa cikin yatsunka da yatsun kafa da zub da jini a cikin hanci da gumis.

WM na ƙarshe zai iya shafar gabobin, wanda ke haifar da kumburi a cikin hanta, saifa, da ƙugiyoyin lymph. Hyperviscosity daga cutar na iya haifar da rashin gani ko matsaloli game da gudan jini zuwa cikin kwayar ido.

Cutar kansar na iya haifar da cututtukan bugun jini daga ƙarshe saboda rashin zagayawar jini zuwa kwakwalwa, da kuma matsalolin zuciya da koda.

5. Shin Waldenstrom macroglobulinemia yana gudana a cikin iyalai?

Masana kimiyya har yanzu suna nazarin WM, amma sun yi imanin cewa kwayoyin halittar da aka gada na iya kara wa wasu damar damar kamuwa da cutar.

Kusan kashi 20 cikin 100 na mutanen da ke da wannan nau'in cutar sankara suna da alaƙar kut-da-kut da wani mai cutar WM ko wata cuta da ke haifar da ƙwayoyin halittar B.

Yawancin mutanen da aka gano da WM ba su da tarihin rashin lafiyar. Yawanci yakan faru ne sakamakon maye gurbi na kwayoyin halitta, wadanda ba a gadonsu, a tsawon rayuwar mutum.

6. Me ke haifar da Waldenstrom macroglobulinemia?

Masana kimiyya basu gano ainihin abin da ke haifar da WM ba. Bayanai sun nuna cewa cakudewar kwayoyin halittu, muhalli, da kwayoyin cuta a tsawon rayuwar wani na iya haifar da ci gaban cutar.

Wani maye gurbi na kwayar halitta MYD88 yana faruwa a kusan kashi 90 cikin ɗari na mutanen da ke tare da Waldenstrom macroglobulinemia, a cewar Gidauniyar Macroglobulinemia ta International Waldenstrom (IWMF).

Wasu bincike sun gano alaƙa tsakanin cutar hepatitis C da WM a cikin wasu (amma ba duka ba) mutanen da ke da cutar.

Bayyana abubuwa ga fata, roba, solvents, dyes, da paints na iya zama mahimmin abu a wasu lokuta na WM. Bincike kan abin da ke haifar da WM yana gudana.

7. Har yaushe zaku iya zama tare da Waldenstrom macroglobulinemia?

Binciken da aka yi kwanan nan ya nuna cewa ana sa ran rabin mutanen da ke tare da WM za su rayu tsawon shekaru 14 zuwa 16 bayan ganowar cutar su, a cewar IWMF.

Halinku na mutum na iya bambanta dangane da:

• shekarunka
• kiwon lafiya gaba daya
• yadda saurin cutar ke ci gaba

Ba kamar sauran nau'o'in ciwon daji ba, ba a bincikar WM a matakai ba. Madadin haka, likitoci suna amfani da Tsarin Neman Tsarin Gaggawa don Waldenstrom Macroglobulinemia (ISSWM) don kimanta ra'ayinku.

Wannan tsarin yana la'akari da abubuwa da dama, gami da:

• shekaru
• matakin haemoglobin jini
• lissafin platelet
• beta-2 microglobulin matakin
• matakin IgM na monoclonal

Dangane da ƙididdigar ku don waɗannan abubuwan haɗarin, likitanku na iya sanya ku a cikin ƙananan, tsaka-tsaka, ko ƙungiyar haɗari mai haɗari, wanda zai iya taimaka muku don fahimtar hangen naku mafi kyau.

Adadin rayuwa na shekaru 5 ga mutanen da ke cikin rukunin masu kasada kaso 87, rukunin masu matsakaicin kasada shi ne kaso 68, sannan kuma masu kasada mai kasada kaso 36, a cewar kungiyar masu cutar kansa ta Amurka.

Wadannan kididdigar sun dogara ne akan bayanai daga mutane 600 da aka gano tare da WM kuma aka magance su kafin watan Janairun 2002.

Sabbin jiyya na iya samar da kyakkyawan fata.

8. Shin Waldenstrom macroglobulinemia zai iya maye gurbinsa?

Ee. WM yana shafar ƙwayoyin lymphatic, wanda ake samu a ɓangarorin jiki da yawa. A lokacin da mutum ya kamu da cutar, tuni ana iya samun sa a cikin jini da kashin kashi.

Daga nan zai iya yaduwa zuwa mahaifa, hanta, da baƙin ciki. A cikin wasu lamura da ba kasafai ake samun su ba, WM na iya yin metastasize a cikin ciki, glandar thyroid, fata, huhu, da hanji.

9. Yaya ake kula da Waldenstrom macroglobulinemia?

Jiyya don WM ya bambanta daga mutum zuwa mutum kuma gabaɗaya baya farawa har sai kun sami alamomi daga cutar. Wasu mutane na iya buƙatar magani har sai 'yan shekaru bayan ganewar asali.

Likitanku na iya ba da shawarar fara magani lokacin da wasu sharuɗɗan da ke haifar da cutar kansa suka kasance, gami da:

• cututtukan hyperviscosity
• karancin jini
• lalacewar jijiya
• matsalolin gabobi
• amyloidosis
• cryoglobulins

Akwai magunguna iri-iri don taimaka maka gudanar da alamomin cutar. Magungunan gama gari na WM sun haɗa da:

• plasmapheresis
• jiyyar cutar sankara
• niyya far
• rigakafin rigakafi

A cikin wasu lokuta, likitanku na iya ba da shawarar ƙarancin jiyya na yau da kullun, kamar su:

• cire saifa
• dasa kwayar halitta
• radiation radiation

Takeaway

Kasancewa tare da cutar kansa kamar WM na iya zama ƙwarewa mai yawa.

Koyaya, samun bayanai don taimaka muku fahimtar yanayinku da zaɓuɓɓukan magani, na iya taimaka muku jin ƙwarin gwiwa game da hangen nesa.