Ciwo na ɓoyewar kwayar cutar antidiuretic wanda bai dace ba

Ciwon rashin lafiyar kwayar cuta mai ƙarancin jiki (SIADH) wani yanayi ne wanda jiki yakan haifar da kwayar maganin ƙarancin jini da yawa (ADH). Wannan sinadarin hormone yana taimaka wa kodan wajen sarrafa yawan ruwan da jikinka ke asara ta fitsari. SIADH na sa jiki ya riƙe ruwa da yawa.

ADH wani sinadari ne wanda aka samar dashi ta hanyar halitta a wani yanki na kwakwalwa da ake kira hypothalamus. Bayan haka sai pituitary gland yake kwance a gindin kwakwalwa.

Akwai dalilai da yawa da yasa jiki yake buƙatar yin ADH mai yawa. Yanayi na gama gari lokacinda ADH aka sakashi cikin jini lokacinda baza ayi shi ba (bai dace ba) sun hada da:

• Magunguna, kamar wasu nau'in ciwon sukari na nau'in 2, magungunan kamawa, masu kwantar da hankali, magungunan zuciya da na hawan jini, magungunan kansar, maganin sa barci
• Yin tiyata a ƙarƙashin ƙwayar rigakafi
• Rashin hankali na kwakwalwa, kamar rauni, cututtuka, bugun jini
• Yin tiyatar kwakwalwa a cikin yankin hypothalamus
• Cutar huhu, irin su ciwon huhu, tarin fuka, kansar, cututtukan da ke ci gaba

Causesananan dalilai sun haɗa da:

• Diseasesananan cututtuka na hypothalamus ko pituitary
• Ciwon daji na huhu, karamin hanji, pancreas, kwakwalwa, cutar sankarar bargo
• Rashin hankali

Tare da SIADH, fitsarin yana matse sosai. Ba a fitar da isasshen ruwa kuma akwai ruwa da yawa a cikin jini. Wannan yana narke abubuwa da yawa a cikin jini kamar sodium. Levelarancin sodium mai ƙarancin jini shine mafi yawancin sanadin alamun bayyanar ADH da yawa.

Sau da yawa, babu alamun alamun daga ƙananan matakin sodium.

Lokacin da bayyanar cututtuka ta faru, zasu iya haɗawa da ɗayan masu zuwa:

• Tashin zuciya da amai
• Ciwon kai
• Matsaloli tare da daidaito wanda na iya haifar da faɗuwa
• Canje-canjen tunani, kamar rikicewa, matsalolin ƙwaƙwalwar ajiya, baƙon hali
• Kamawa ko suma, a cikin mawuyacin yanayi

Mai ba da sabis na kiwon lafiya zai yi cikakken bincike na jiki don taimakawa tantance dalilin alamunku.

Gwajin gwaje-gwaje wanda zai iya tabbatarwa da taimakawa gano ƙananan sodium sun haɗa da:

• M rayuwa panel (ya hada da jini sodium)
• Gwajin jini na Osmolality
• Fitsarin cikin ruwa
• Fitsarin sodium
• Allon toxicology don wasu magunguna
• Kuna iya buƙatar yin karatun hoto don samarin huhu da ƙwaƙwalwar huhu da gwajin gwajin ƙwaƙwalwa a cikin yara da ake zargin suna da SIADH

Jiyya ya dogara da dalilin matsalar. Misali, ana yin tiyata don cire wani kumburi wanda ke samar da ADH. Ko kuma, idan magani ne musabbabin, ana iya canza sashinta ko a gwada wani magani.

A kowane hali, matakin farko shi ne takaita shan ruwa. Wannan yana taimakawa hana yawan ruwa daga ginawa cikin jiki. Mai ba ku sabis zai gaya muku yadda yawan yawan shan ruwanku na yau da kullun zai kasance.

Za a iya buƙatar magunguna don toshe tasirin ADH a kan kodan don kodar ta fitar da ruwa mai yawa. Wadannan magunguna za'a iya basu a matsayin kwaya ko kuma allura da aka basu a jijiyoyin jini (intravenous).

Sakamakon ya dogara da yanayin da ke haifar da matsalar. Soananan sodium da ke faruwa cikin sauri, a ƙasa da awanni 48 (m hyponatremia), ya fi haɗari fiye da ƙananan sodium da ke tasowa a hankali a kan lokaci. Lokacin da matakin sodium ya faɗi sannu a hankali tsawon kwanaki ko makonni (na kullum hyponatremia), ƙwayoyin kwakwalwa suna da lokaci don daidaitawa kuma ƙananan alamu irin su kumburin kwakwalwa ba sa faruwa. Tsarin hyponatremia na yau da kullun yana haɗuwa da matsalolin tsarin damuwa kamar rashin daidaituwa da ƙwaƙwalwar ajiya. Yawancin dalilan SIADH suna da juyawa.

A cikin yanayi mai tsanani, ƙaramin sodium na iya haifar da:

• Rage sani, raayi ko wauta
• Bayanin kwakwalwa
• Mutuwa

Lokacin da matakin sodium na jikinka ya sauka da yawa, zai iya zama gaggawa mai barazanar rai. Kira mai ba ku sabis nan da nan idan kuna da alamun wannan yanayin.

SIADH; Rashin dacewa ɓoye na kwayar cutar antidiuretic; Ciwon rashin fitowar ADH mara dacewa; Ciwon cututtukan antidiures na rashin dacewa

Hannon MJ, Thompson CJ. Vasopressin, insipidus na ciwon sukari, da kuma ciwo na cututtukan antidiuresis marasa dacewa. A cikin: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Manya da Yara. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 18.

Verbalis JG. Rikici na daidaita ruwa. A cikin: Skorecki K, Chertow GM, Marsden PA, Taal MW, Yu ASL, eds. Brenner da Rector na Koda. 10 ed. Philadelphia, PA: Elsevier; 2016: babi na 16.