Ciwon Zollinger-Ellison

Ciwon Zollinger-Ellison wani yanayi ne wanda cikin jiki ke samar da yawancin hormone gastrin. Mafi yawan lokuta, karamin kumburi (gastrinoma) a cikin pancreas ko ƙananan hanji shine asalin ƙarin gastrin a cikin jini.

Ciwon Zollinger-Ellison yana haifar da ciwace-ciwace. Wadannan ci gaban galibi ana samunsu ne a cikin kan pancreas da ƙananan hanjinsa na sama. Ana kiran kumburin ciki gastrinomas. Babban matakin gastrin yana haifar da yawan ruwan ciki na ciki.

Gastrinomas yana faruwa azaman ƙari guda ɗaya ko ƙari da yawa. Halfaya daga rabi zuwa biyu bisa uku na gastrinomas guda ɗaya sune ciwace-ciwacen ƙwayoyin cuta. Waɗannan ciwace-ciwacen sukan bazu zuwa hanta da ƙwayoyin lymph na kusa.

Mutane da yawa tare da gastrinomas suna da ƙari mai yawa a matsayin ɓangare na yanayin da ake kira nau'in endoprin neoplasia I (MEN I). Tumurai na iya tasowa a cikin gland (kwakwalwa) da parathyroid gland (wuyansa) da kuma cikin ƙoshin ciki.

Kwayar cutar na iya haɗawa da:

• Ciwon ciki
• Gudawa
• Jinin amai (wani lokacin)
• Symptomsananan alamun cututtukan hanji (GERD)

Alamomin sun hada da ulce a cikin ciki da karamin hanji.

Gwajin sun hada da:

• CT scan na ciki
• Gwajin jiko na alli
• Endoscopic duban dan tayi
• Yin aikin tiyata
• Matsayin jinin Gastrin
• Binciken Octreotide
• Gwajin gwaji na sirri

Ana amfani da magungunan da ake kira proton pump inhibitors (omeprazole, lansoprazole, da sauransu) don magance wannan matsalar. Wadannan kwayoyi suna rage yawan acid a ciki. Wannan yana taimakawa maruru da ke ciki da karamin hanji su warke. Wadannan magunguna kuma suna magance ciwon ciki da gudawa.

Za a iya yin aikin tiyata don cire ciwon ciki guda ɗaya idan ƙari bai bazu zuwa wasu gabobin ba. Yin tiyata a cikin ciki (gastrectomy) don sarrafa ƙarancin acid ba safai ake buƙata ba.

Yawan maganin ba shi da yawa, koda kuwa an same shi da wuri kuma an cire kumburin. Koyaya, gastrinomas suna girma ahankali.Mutanen da ke da wannan yanayin na iya rayuwa tsawon shekaru bayan da aka gano kumburin. Magungunan kawar da ƙwayar cuta suna aiki sosai don sarrafa alamun.

Matsaloli na iya haɗawa da:

• Rashin gano tumbin lokacin tiyata
• Zuban ciki ko rami (perforation) daga ulce a cikin ciki ko duodenum
• Tsananin gudawa da rage nauyi
• Yada kumburin zuwa wasu gabobin

Kira wa mai ba da lafiyar ku idan kuna da matsanancin ciwon ciki wanda ba zai tafi ba, musamman idan ya faru da gudawa.

Ciwon Z-E; Gastrinoma

• Endocrine gland

Jensen RT, Norton JA, Oberg K. Ciwan daji na Neuroendocrine. A cikin: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger da Cututtukan Cutar hanta da na Fordtran. 10 ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 33.

Vella A. hormones na hanji da gut endocrine ƙari. A cikin: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Littafin Williams na Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: babi na 38.