Zazzaɓin Bahar Rum na Iyalai

Zazzaɓin Zazzaɓin Yankin Bahar Rum (FMF) cuta ce da ba ta cika faruwa ba ta hanyar dangi (wanda aka gada). Ya ƙunshi zazzaɓi mai maimaitawa da kumburi wanda sau da yawa yakan shafi rufin ciki, kirji, ko haɗin gwiwa.

FMF galibi ana haifar dashi ne ta hanyar maye gurbi a cikin wani jinsi mai suna MEFV. Wannan kwayar halitta tana haifar da furotin da ke tattare da sarrafa kumburi. Cutar ta bayyana ne kawai a cikin mutanen da suka karɓi kwafi biyu na canjin yanayin, ɗayan daga kowane mahaifa. Wannan shi ake kira autosomal recessive.

FMF galibi yana shafar mutanen kakannin Bahar Rum. Wadannan sun hada da yahudawa, Armeniyawa, da Larabawa wadanda ba Ashkenazi (Sephardic) ba. Hakanan mutane daga wasu ƙabilun na iya shafa.

Kwayar cutar yawanci tana farawa ne tsakanin shekaru 5 zuwa 15. Kumburi a cikin rufin ramin ciki, kogon kirji, fata, ko haɗin gwaiwa yana faruwa tare da manyan zazzaɓi waɗanda yawanci sukan kan yi awa 12 zuwa 24. Hare-hare na iya bambanta da tsananin alamun bayyanar. Mutane galibi ba su da alamun alama tsakanin hare-hare.

Kwayar cutar na iya haɗawa da maimaita lokuta na:

• Ciwon ciki
• Ciwon kirji mai kaifi kuma yana daɗa muni yayin shan numfashi
• Zazzabi ko musanya sanyi da zazzabi
• Hadin gwiwa
• Ciwon fata (raunuka) waɗanda suke ja da kumbura kuma suna da nisa daga 5 zuwa 20 cm a diamita

Idan gwajin kwayoyin ya nuna cewa kana da MEFV maye gurbin kwayar halitta da alamun cutarku sun dace da tsarin al'ada, ganewar asali ya kusan tabbata. Gwajin dakunan gwaje-gwaje ko x-ray na iya kawar da wasu cututtukan da za su iya taimakawa don ganewar asali.

Matakan wasu gwaje-gwajen jini na iya zama sama da yadda aka saba lokacin da aka yi yayin kai hari. Gwaje-gwaje na iya haɗawa da:

• Cikakken ƙidayar jini (CBC) wanda ya haɗa da ƙididdigar ƙwayar jinin jini
• C-mai amsa furotin don bincika kumburi
• Erythrocyte sedimentation rate (ESR) don bincika kumburi
• Gwajin Fibrinogen don bincika daskarewar jini

Manufar magani ga FMF shine sarrafa alamun. Colchicine, maganin da ke rage kumburi, na iya taimakawa yayin hari kuma na iya hana ƙarin hare-hare. Hakanan zai iya taimakawa wajen hana wata matsala mai tsanani da ake kira amyloidosis systemic, wanda yake gama gari ga mutane tare da FMF.

Ana iya amfani da NSAIDs don magance zazzaɓi da zafi.

Babu sanannen magani ga FMF. Mafi yawan mutane na ci gaba da samun hare-hare, amma yawan hare-hare da kuma tsanani ya bambanta daga mutum zuwa mutum.

Amyloidosis na iya haifar da lalacewar koda ko rashin samun damar shan abubuwan gina jiki daga abinci (malabsorption). Matsalar haihuwa a cikin mata da maza da kuma amosanin gabbai suma matsaloli ne.

Tuntuɓi mai ba da sabis idan kai ko ɗanka sun kamu da alamun wannan yanayin.

Iyalan gidan paroxysmal polyserositis; Peritonitis na lokaci-lokaci; Maimaita polyserositis; Cutar sankarar iska mai laushi; Cutar lokaci-lokaci; Zazzabi na lokaci-lokaci; FMF

• Gwargwadon yanayin zafi

Labaran JW. Ciwon cututtukan zazzabi na lokaci-lokaci da sauran cututtukan cututtukan ƙwayoyin cuta. A cikin: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Littafin koyar da ilimin yara. 21st ed. Philadelphia, PA: Elsevier; 2020: babi na 188.

Shohat M. Zazzabi na Iyalin Bahar Rum. A cikin: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, eds. GeneReviews [Intanet]. Jami'ar Washington, Seattle, WA: 2000 Aug 8 [sabunta 2016 Dec 15]. PMID: 20301405 www.pubmed.ncbi.nlm.nih.gov/20301405/.