Calcium pyrophosphate amosanin gabbai

Calcium pyrophosphate dihydrate (CPPD) amosanin gabbai cuta ce ta haɗin gwiwa wacce ke iya haifar da hare-haren cututtukan zuciya. Kamar gout, lu'ulu'u ne a cikin gidajen. Amma a cikin wannan amosanin gabbai, ba a ƙirƙirar lu'ulu'u ne daga uric acid.

Bayyanar da sinadarin calcium pyrophosphate dihydrate (CPPD) yana haifar da wannan nau'i na amosanin gabbai. Ginin wannan sinadarin ya zama lu'ulu'u ne a cikin guringuntsi na haɗin gwiwa. Wannan yana haifar da hare-haren kumburin haɗin gwiwa da zafi a gwiwoyi, wuyan hannu, ƙafafun kafa, kafaɗa da sauran haɗin gwiwa. Ya bambanta da gout, haɗin metatarsal-phalangeal na babban yatsan hannu ba zai shafa ba.

Daga cikin tsofaffi, CPPD shine sanadin cututtukan cututtukan zuciya a cikin haɗin gwiwa ɗaya. An kai harin ta hanyar:

• Rauni ga haɗin gwiwa
• Allurar hyaluronate a cikin mahaɗin
• Rashin lafiyar likita

CPPD amosanin gabbai yafi shafar tsofaffi saboda lalacewar haɗin gwiwa da osteoarthritis yana ƙaruwa tare da shekaru. Irin wannan lalacewar haɗin gwiwa yana ƙaruwa da halin sakawar CPPD. Koyaya, cututtukan cututtukan zuciya na CPPD na iya shafar samari wasu lokuta waɗanda ke da yanayi kamar:

• Hemochromatosis
• Parathyroid cuta
• Ciwon koda na dogaro da ƙwanƙwasawa

A mafi yawan lokuta, cututtukan cututtukan CPPD ba sa haifar da wata alama. Madadin haka, x-haskoki na haɗin gwiwa da abin ya shafa kamar gwiwoyi suna nuna alamun adadi na alli.

Wasu mutanen da ke da ɗakunan ajiya na CPPD a cikin manyan gidajen abinci na iya samun alamun bayyanar masu zuwa:

• Jin zafi
• Kumburi
• Dumi-dumi
• Redness

Hare-hare na haɗin gwiwa na iya wucewa tsawon watanni. Babu alamun bayyanar cututtuka tsakanin hare-hare.

A cikin wasu mutane CPPD amosanin gabbai yana haifar da mummunar lalacewa ga haɗin gwiwa.

Cutar cututtukan CPPD na iya faruwa a cikin kashin baya, duka na ƙasa da na sama. Matsi akan jijiyoyin kashin baya na iya haifar da ciwo a hannu ko ƙafa.

Saboda alamun suna kama da juna, cututtukan cututtukan zuciya na CPPD na iya rikicewa da:

• Ciwon amosanin gabbai (gout)
• Osteoarthritis
• Rheumatoid amosanin gabbai

Yawancin yanayin arthritic suna nuna alamun bayyanar. Kulawa da hankali ga ruwan haɗin gwiwa don lu'ulu'u na iya taimakawa likita gano yanayin.

Kuna iya yin gwaje-gwaje masu zuwa:

• Gwajin ruwa na haɗin gwiwa don gano farin ƙwayoyin jini da alli pyrophosphate lu'ulu'u
• Hanyoyin haɗin gwiwa don neman lalacewar haɗin gwiwa da ƙwayoyin calcium a cikin sararin haɗin gwiwa
• Sauran gwaje-gwajen hotunan haɗin gwiwa kamar su CT scan, MRI ko duban dan tayi, idan an buƙata
• Gwajin jini don binciko yanayin da ke da alaƙa da alli pyrophosphate amosanin gabbai

Jiyya na iya haɗawa da cire ruwa don taimakawa matsa lamba a cikin haɗin gwiwa. Ana sanya allura a cikin mahaɗin kuma ana so a sa ruwa. Wasu zaɓuɓɓukan magani na yau da kullun sune:

• Injections na Steroid: don magance kumbura haɗin gwiwa mai tsanani
• Magungunan maganin baka: don magance mahaɗar kumbura da yawa
• Magungunan cututtukan cututtukan ƙwayoyin cuta (NSAIDs): don sauƙaƙe ciwo
• Colchicine: don magance hare-haren cututtukan zuciya na CPPD
• Don cututtukan cututtukan CPPD na yau da kullun a cikin ɗakunan mahaɗa da yawa methotrexate ko hydroxychloroquine na iya zama taimako

Yawancin mutane suna yin kyau tare da magani don rage mummunan haɗin haɗin gwiwa. Magunguna kamar su colchicine na iya taimakawa hana sake kai hari. Babu magani don cire lu'ulu'u na CPPD.

Lalacewar haɗin gwiwa na dindindin na iya faruwa ba tare da magani ba.

Kira mai ba da sabis na kiwon lafiya idan kuna da hare-haren haɗin kumburi da haɗin gwiwa.

Babu wata hanyar da aka sani don hana wannan cuta. Koyaya, magance wasu matsalolin da zasu iya haifar da cututtukan zuciya na CPPD na iya sa yanayin ya zama mai tsanani.

Ziyartar bin diddigi na yau da kullun na iya taimakawa hana lalacewar gidajen da abin ya shafa.

Calcium pyrophosphate cutar rashin ruwa; Cutar CPPD; Ciwon / cututtukan cututtukan CPPD; Takamatsu; Pyrophosphate arthropathy; Chondrocalcinosis

• Kafada hadin gwiwa kumburi
• Osteoarthritis
• Tsarin haɗin gwiwa

Andrés M, Sivera F, Pascual E. Far don CPPD: zaɓuɓɓuka da shaida. Curr Rheumatol Rep. 2018; 20 (6): 31. PMID: 29675606 pubmed.ncbi.nlm.nih.gov/29675606/.

Edwards NL. Cutar cututtukan Crystal. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 257.

Terkeltaub R. Calcium crystal cuta: calcium pyrophosphate dihydrate da ainihin alli phosphate. A cikin: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Littafin Kelley da Firestein na Rheumatology. 10 ed. Philadelphia, PA: Elsevier; 2017: babi na 96.