Polymyositis - balagagge

Polymyositis da dermatomyositis sune cututtukan cututtukan ƙwayoyin cuta. (Yanayin ana kiransa dermatomyositis lokacin da ya shafi fata.) Waɗannan cututtukan suna haifar da raunin tsoka, kumburi, taushi, da lalacewar nama. Su wani ɓangare ne na babbar ƙungiyar cututtukan da ake kira myopathies.

Polymyositis yana shafar tsokoki. Haka kuma an san shi azaman myopathy na idiopathic. Ba a san ainihin musabbabin abin ba, amma yana iya kasancewa yana da alaƙa da saurin haɗuwa da nakasa ko kamuwa da cuta.

Polymyositis na iya shafar mutane a kowane zamani. An fi samun hakan ga manya tsakanin shekaru 50 zuwa 60, da kuma cikin manyan yara. Yana shafar mata sau biyu kamar na maza. Ya fi zama ruwan dare a cikin Baƙin Amurkawa fiye da fararen fata.

Polymyositis cuta ce ta tsari. Wannan yana nufin yana shafar dukkan jiki. Raunin tsoka da taushi na iya zama alamun polymyositis. Rushewa alama ce ta yanayin da ke da alaƙa, dermatomyositis.

Kwayar cutar ta yau da kullun sun haɗa da:

• Raunin tsoka a kafadu da kwatangwalo. Wannan na iya sa ya zama da wuya a daga hannaye sama da kai, tashi daga wurin zama, ko hawa matakala.
• Matsalar haɗiyewa.
• Ciwon tsoka.
• Matsaloli tare da murya (wanda ya haifar da rauni na jijiyoyin wuya).
• Rashin numfashi.

Hakanan kuna iya samun:

• Gajiya
• Zazzaɓi
• Hadin gwiwa
• Rashin ci
• Iffarfin safe
• Rage nauyi
• Fuskar fata a bayan yatsun hannu, a kan ƙasan ido, ko a fuska

Gwaje-gwaje na iya haɗawa da:

• Magungunan autoimmune da gwajin kumburi
• CPK
• Magani aldolase
• Kayan lantarki
• MRI na tsokoki
• Gwajin tsoka
• Myoglobin a cikin fitsari
• ECG
• Kirjin x-ray da hoton CT na kirji
• Gwajin aikin huhu
• Nazarin haɗiye Esophageal
• Myositis takamaimai kuma hade autoantibodies

Har ila yau, dole ne a lura da mutanen da ke da wannan yanayin a hankali don alamun kansar.

Babban magani shine amfani da magungunan corticosteroid. Yawan maganin a hankali yana narkar dasu yayin da karfin tsoka ya inganta. Wannan yana ɗaukar makonni 4 zuwa 6. Za ku zauna kan ƙaramin kashi na maganin corticosteroid bayan wannan.

Ana iya amfani da magunguna don murƙushe garkuwar jiki don maye gurbin corticosteroids. Wadannan kwayoyi na iya hada da azathioprine, methotrexate ko mycophenolate.

Don cutar da ke ci gaba da aiki duk da corticosteroids, an gwada gamma globulin cikin jini tare da sakamako mai haɗewa. Hakanan za'a iya amfani da magungunan ƙwayoyin cuta. Rituximab ya bayyana shine mafi alkawuran. Yana da mahimmanci a fitar da wasu sharuɗɗa a cikin mutanen da basa karɓar magani. Ana iya buƙatar maimaita biopsy na tsoka don yin wannan ganewar asali.

Idan yanayin yana hade da ƙari, zai iya inganta idan an cire kumburin.

Amsawa ga magani ya bambanta, dangane da rikitarwa. Kusan 1 cikin 5 mutane na iya mutuwa cikin shekaru 5 da haɓaka yanayin.

Mutane da yawa, musamman yara, suna murmurewa daga rashin lafiya kuma basa buƙatar ci gaba da magani. Ga mafi yawan manya, duk da haka, ana buƙatar magungunan rigakafi don magance cutar.

Hangen nesa ga mutanen da ke fama da cutar huhu tare da anti-MDA-5 antibody ba shi da kyau duk da magani na yanzu.

A cikin manya, mutuwa na iya haifar da:

• Rashin abinci mai gina jiki
• Namoniya
• Rashin numfashi
• Mai tsanani, rauni na dogon lokaci

Babban abin da ke haddasa mutuwa sune cutar daji da cutar huhu.

Matsaloli na iya haɗawa da:

• Adadin alli a cikin tsokoki da abin ya shafa, musamman a yara masu cutar
• Ciwon daji
• Ciwon zuciya, cututtukan huhu, ko rikitarwa na ciki

Kira mai ba da sabis na kiwon lafiya idan kuna da alamun wannan cuta. Nemi magani na gaggawa idan kana da rashin numfashi da wahalar haɗiye.

• Musclesananan tsokoki na baya

Aggarwal R, Rider LG, Ruperto N, et al. Kwalejin Kwalejin Rheumatology ta Amurka ta 2016 / Leagueungiyar Turai game da Tsarin Rheumatism don imalananan, Matsakaici, da Babban Maganin Magani a Adult Dermatomyositis da Polymyositis: Mungiyar Myositis ta Duniya da Studiesungiyar Nazarin Clinical / ediwararren ediwararren Rwararrun Rwararrun ediwararrun ediwararru ta ediasa. Arthritis Rheumatol. 2017; 69 (5): 898-910. PMID: 28382787 www.ncbi.nlm.nih.gov/pubmed/28382787.

Dalakas MC. Cututtukan tsoka mai kumburi. N Engl J Med. 2015; 373 (4): 393-394. PMID: 26200989 www.ncbi.nlm.nih.gov/pubmed/26200989.

Greenberg SA. Myopathies mai kumburi. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 269.

Nagaraju K, Gladue HS, Lundberg IE.Cututtukan kumburi na tsoka da sauran ƙwayoyin cuta. A cikin: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Littafin Kelley da Firestein na Rheumatology. 10 ed. Philadelphia, PA: Elsevier; 2017: babi na 85.

Yoshida N, Okamoto M, Kaieda S, et al. Ofungiyar anti-aminoacyl-transfer RNA synthetase antibody da anti-melanoma bambancin hade-hade da kwayar cutar ta 5 tare da maganin warkewar cutar polymyositis / cututtukan huhu da ke hade da cutar huhu. Binciken Respir. Zane. 2017; 55 (1): 24-32. PMID: 28012490 www.ncbi.nlm.nih.gov/pubmed/28012490.