Protein electrophoresis - magani

Wannan gwajin gwajin yana auna nau'ikan furotin a cikin ruwa (sashin) wani sashi na samfurin jini. Wannan ruwa shi ake kira serum.

Ana bukatar samfurin jini.

A cikin dakin gwaje-gwaje, ma'aikacin ya sanya samfurin jini akan takarda ta musamman kuma ya yi amfani da wutar lantarki. Sunadaran suna motsawa akan takarda kuma suna yin makada wadanda suke nuna adadin kowace sunadarin.

Ana iya tambayarka kada ku ci ko sha na awanni 12 kafin wannan gwajin.

Wasu magunguna na iya shafar sakamakon wannan gwajin. Mai ba ku kiwon lafiya zai gaya muku idan kuna buƙatar dakatar da shan kowane magani. Kada ka dakatar da kowane magani kafin magana da mai baka.

Lokacin da aka saka allurar don zana jini, wasu mutane suna jin matsakaicin ciwo. Wasu kuma suna jin ƙyalli ko harba. Bayan haka, ƙila za a sami wasu harbi ko ɗan rauni. Wannan da sannu zai tafi.

Sunan sunadarai daga amino acid ne kuma sune mahimman sassan sassan kwayoyi da kyallen takarda. Akwai nau’ikan sunadarai daban-daban a jiki, kuma suna da ayyuka daban-daban. Misalan sunadarai sun hada da enzymes, wasu kwayoyin hormones, haemoglobin, low-density lipoprotein (LDL, or bad cholesterol), da sauransu.

Magungunan sunadarai ana rarraba su albumin ko globulins. Albumin shine mafi yawan furotin a cikin magani. Yana ɗauke da ƙananan ƙwayoyi masu yawa. Hakanan yana da mahimmanci don kiyaye ruwa daga malala daga jijiyoyin jini zuwa cikin kyallen takarda.

Globulins sun kasu kashi-1, alpha-2, beta da gamma globulins. Gabaɗaya, matakan furotin alpha da gamma globulin suna ƙaruwa yayin da akwai kumburi a jiki.

Lipoprotein electrophoresis yana tantance yawan sunadaran da suka kunshi furotin da mai, wanda ake kira lipoproteins (kamar su LDL cholesterol).

Jeri masu darajar al'ada sune:

• Jimlar furotin: 6.4 zuwa 8.3 gram a kowace deciliter (g / dL) ko kuma 64 zuwa 83 a kowace lita (g / L)
• Albumin: 3.5 zuwa 5.0 g / dL ko 35 zuwa 50 g / L.
• Alpha-1 globulin: 0.1 zuwa 0.3 g / dL ko 1 zuwa 3 g / L
• Alpha-2 globulin: 0.6 zuwa 1.0 g / dL ko 6 zuwa 10 g / L.
• Beta globulin: 0.7 zuwa 1.2 g / dL ko 7 zuwa 12 g / L.
• Gamma globulin: 0.7 zuwa 1.6 g / dL ko 7 zuwa 16 g / L.

Misalan da ke sama ma'auni ne gama gari don sakamakon waɗannan gwaje-gwajen. Jeri na darajar yau da kullun na iya ɗan bambanta kaɗan tsakanin ɗakunan gwaje-gwaje daban-daban. Wasu leburori suna amfani da ma'auni daban daban ko gwada samfuran daban. Yi magana da mai baka game da ma'anar takamaiman sakamakon ka.

Rage yawan furotin na iya nuna:

• Rashin ɓarkewar sunadari mai narkewa daga tsarin narkewar abinci ko rashin iyawar narkewar abinci don shafan sunadarai (cututtukan da ke rasa furotin)
• Rashin abinci mai gina jiki
• Ciwon koda da ake kira ciwo na nephrotic
• Raunin hanta da aikin hanta mara kyau (cirrhosis)

Proteara yawan furotin na alpha-1 globulin na iya kasancewa saboda:

• M cututtukan kumburi
• Ciwon daji
• Cutar rashin kumburi na yau da kullun (alal misali, cututtukan rheumatoid, SLE)

Rage furotin na alpha-1 globulin na iya zama alamar:

• Alpha-1 karancin antitrypsin

Proteara yawan furotin na alpha-2 globulin na iya nuna a:

• M ƙonewa
• Konewa na kullum

Rage furotin na alpha-2 globulin na iya nuna:

• Rushewar jajayen ƙwayoyin jini (hemolysis)

Proteara yawan furotin beta globulin na iya nunawa:

• Rashin lafiya wanda jiki ke da matsala wajen ragargaza ƙwayoyi (misali, hyperlipoproteinemia, familial hypercholesterolemia)
• Maganin Estrogen

Rage beta sunadaran globulin na iya nuna:

• Lowananan ƙananan matakin LDL cholesterol
• Rashin abinci mai gina jiki

Karin sunadaran gamma globulin na iya nuna:

• Ciwon daji na jini, gami da myeloma mai yawa, Waldenström macroglobulinemia, lymphomas, da cutar sankarar bargo mai tsafta
• Cutar rashin kumburi na yau da kullun (alal misali, cututtukan zuciya na rheumatoid)
• M kamuwa da cuta
• Ciwon hanta na kullum

Akwai 'yar hatsarin da ke tattare da daukar jininka. Jijiyoyi da jijiyoyin jini sun bambanta da girma daga mutum ɗaya zuwa wancan, kuma daga wannan gefe na jiki zuwa wancan. Bloodaukar jini daga wasu mutane na iya zama da wahala fiye da wasu.

Sauran haɗarin da ke tattare da ɗaukar jinni ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Mahara huda don gano wuri jijiyoyinmu
  
• Hematoma (haɓakar jini a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

FATAWA

• Gwajin jini

Chernecky CC, Berger BJ. Protein electrophoresis - magani. A cikin: Chernecky CC, Berger BJ, eds. Gwajin Laboratory da hanyoyin bincike. Na 6 ed. St Louis, MO: Elsevier Saunders; 2013: 917-920.

Munshi NC, Jagannath S. Plasma cell neoplasms. A cikin: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Ka'idoji da Aiki. 7th ed. Philadelphia, PA: Elsevier; 2018: babi na 86.

Warner EA, Herold AH. Fassara gwaje-gwajen dakin gwaje-gwaje. A cikin: Rakel RE, Rakel DP, eds. Littafin karatun Magungunan Iyali. 9th ed. Philadelphia, PA: Elsevier; 2016: babi na 14.