Ciwon Serotonin

Ciwon Serotonin (SS) mummunan tasirin magani ne mai barazanar rai. Yana sanya jiki samun serotonin da yawa, wani sinadari da ƙwayoyin jijiyoyi ke samarwa.

SS galibi yana faruwa ne yayin da aka sha magunguna biyu da ke shafar matakin jikin serotonin a lokaci guda. Magunguna suna sa serotonin da yawa a sake shi ko kuma ya kasance a yankin ƙwaƙwalwa.

Misali, zaka iya kamuwa da wannan ciwo idan ka sha magungunan migraine da ake kira triptans tare da magungunan kashe kumburi da ake kira serotonin reuptake inhibitors (SSRIs), da serotonin / norepinephrine reuptake inhibitors (SSNRIs).

SSRIs gama gari sun haɗa da citalopram (Celexa), sertraline (Zoloft), fluoxetine (Prozac), paroxetine (Paxil), da escitalopram (Lexapro). SSNRIs sun haɗa da duloxetine (Cymbalta), venlafaxine (Effexor), Desvenlafaxine (Pristiq), Milnacipran (Savella), da Levomilnacipran (Fetzima). Triwararrun masu haɗaka sun haɗa da sumatriptan (Imitrex), zolmitriptan (Zomig), frovatriptan (Frova), rizatriptan (Maxalt), almotriptan (Axert), naratriptan (Amerge), da eletriptan (Relpax).

Idan ka sha waɗannan magungunan, tabbas ka karanta gargaɗin akan marufin. Yana gaya muku game da yiwuwar cutar serotonin. Koyaya, kar ka daina shan maganin ka. Yi magana da likitanka game da damuwarka ta farko.

SS zai iya faruwa yayin farawa ko ƙara magani.

Tsoffin cututtukan cututtukan fata da ake kira monoamine oxidase inhibitors (MAOIs) na iya haifar da SS tare da magungunan da aka bayyana a sama, da meperidine (Demerol, mai ba da magani) ko dextromethorphan (maganin tari).

Hakanan an haɗa magungunan ƙwayoyi, kamar ecstasy, LSD, hodar iblis, da amphetamines tare da SS.

Kwayar cutar tana faruwa tsakanin minutesan mintuna zuwa awanni, kuma na iya haɗawa da:

• Tsanani ko rashin nutsuwa
• Motsa ido mara kyau
• Gudawa
• Saurin bugun zuciya da hawan jini
• Mafarki
• Temperatureara yawan zafin jiki
• Rashin daidaituwa
• Tashin zuciya da amai
• Ayyuka masu saurin aiki
• Canje-canje cikin sauri a cikin jini

Yawanci ana yin binciken ne ta hanyar yiwa mutum tambayoyi game da tarihin likita, gami da nau'ikan magunguna.

Don kamuwa da cutar ta SS, dole ne mutum ya kasance yana shan magani wanda ke canza yanayin sirotonin na jiki (kwayar serotonergic) kuma yana da aƙalla uku daga cikin alamomi ko alamomi masu zuwa:

• Gaggawa
• Movementsunƙun ido mara kyau (ɗumbin ido, mahimmin binciken gano kafa asalin cutar SS)
  
• Gudawa
• Gumi mai nauyi ba saboda aiki ba
• Zazzaɓi
• Halin tunanin mutum ya canza, kamar rikicewa ko hypomania
• Spunƙarar tsoka (myoclonus)
• Hanyoyin motsa jiki (hyperreflexia)
• Shivering
• Tsoro
• Movementsungiyoyin da ba a haɗa su ba (ataxia)

Ba a bincikar SS har sai an kawar da duk wasu abubuwan da ka iya haifar. Wannan na iya haɗawa da cututtuka, maye, matsalolin rayuwa da na hormone, da shan ƙwaya ko shan barasa. Wasu alamun cutar ta SS na iya yin kama da waɗancan saboda yawan shan hodar iblis, lithium, ko MAOI.

Idan mutum ya fara shan ko ƙara yawan sashin kwantar da hankali (kwayar cutar neuroleptic), za a yi la'akari da wasu yanayi kamar su cutar rashin lafiya ta neuroleptic (NMS).

Gwaje-gwaje na iya haɗawa da:

• Al'adun jini (don bincika kamuwa da cuta)
• Kammala ƙididdigar jini (CBC)
• CT scan na kwakwalwa
• Drug (toxicology) da allon barasa
• Matakan lantarki
• Lantarki (ECG)
• Gwajin koda da hanta
• Gwajin aikin thyroid

Mutanen da ke da SS za su iya kasancewa a asibiti a ƙalla awanni 24 don kallo na kusa.

Jiyya na iya haɗawa da:

• Magungunan Benzodiazepine, kamar su diazepam (Valium) ko lorazepam (Ativan) don rage tashin hankali, ƙungiyoyi masu kama da kamawa, da taurin tsoka
• Cyproheptadine (Periactin), magani ne da ke toshe kayan samar da serotonin
• Magunguna (ta cikin jijiya) ruwaye
• Dakatar da magunguna wanda ya haifar da ciwo

A cikin al'amuran da ke barazanar rai, magungunan da ke sanya tsokoki har yanzu (gurguntar da su), da bututun numfashi na ɗan lokaci da injin numfashi za a buƙaci don hana ƙarin lalacewar tsoka.

Mutane na iya yin mummunan rauni a hankali kuma suna iya yin mummunan rashin lafiya idan ba a hanzarta magance su ba. Ba a yi masa magani ba, SS na iya zama na mutuwa. Tare da magani, alamun cuta yawanci suna wucewa ƙasa da awanni 24. Lalacewar gabobi na dindindin na iya haifar, koda da magani.

Rashin karfin tsoka da ba a sarrafawa na iya haifar da mummunan rauni na tsoka. Samfuran da aka samar lokacin da tsokoki suka karye ana sakasu cikin jini kuma daga karshe suna bi ta koda. Wannan na iya haifar da mummunar lalacewar koda idan ba a san SS ba kuma ba a kula da shi da kyau.

Kira mai ba da sabis na kiwon lafiya nan da nan idan kuna da alamun cututtukan serotonin.

Koyaushe gaya wa masu ba ku magungunan da kuke sha. Mutanen da suke ɗaukar ɓoyayye tare da SSRIs ko SSNRIs ya kamata a bi su a hankali, musamman dama bayan fara magani ko ƙara sashi.

Hyperserotonemia; Ciwon Serotonergic; Cutar guba ta Serotonin; SSRI - cututtukan serotonin; MAO - cututtukan serotonin

Fricchione GL, Beach SR, Huffman JC, Bush G, Stern TA. Yanayin barazanar rai a cikin tabin hankali: catatonia, cututtukan cututtukan neuroleptic, da ciwo na serotonin. A cikin: Stern TA, Fava M, Wilens TE, Rosenbaum JF, eds. Babban Asibitin Babban Asibitin Massachusetts. 2nd ed. Philadelphia, PA: Elsevier; 2016: babi na 55.

Levine MD, Ruha AM. Magungunan Magunguna. A cikin: Walls RM, Hockberger RS, Gausche-Hill M, eds. Magungunan gaggawa na Rosen: Ka'idoji da Aikin Gwajin Asibiti. 9th ed. Philadelphia, PA: Elsevier; 2018: babi na 146.

Meehan TJ. Kusanci ga mai cutar mai guba. A cikin: Walls RM, Hockberger RS, Gausche-Hill M, eds. Magungunan gaggawa na Rosen: Ka'idoji da Aikin Gwajin Asibiti. 9th ed. Philadelphia, PA: Elsevier; 2018: babi na 139.