Antineutrophil Cytoplasmic Antibodies (ANCA) Gwaji

Wadatacce

• Mene ne gwajin antioxidrophil cytoplasmic antibodies (ANCA)?
• Me ake amfani da shi?
• Me yasa nake buƙatar gwajin ANCA?
• Menene ya faru yayin gwajin ANCA?
• Shin zan bukaci yin komai don shirya wa gwajin?
• Shin akwai haɗari ga gwajin?
• Menene sakamakon yake nufi?
• Shin akwai wani abin da nake bukatar sani game da gwajin ANCA?
• Bayani

Mene ne gwajin antioxidrophil cytoplasmic antibodies (ANCA)?

Wannan gwajin yana neman antineutrophil cytoplasmic antibodies (ANCA) a cikin jininka. Kwayoyin cuta sune sunadaran da garkuwar jikinku takeyi don yaƙar baƙin abubuwa kamar ƙwayoyin cuta da ƙwayoyin cuta. Amma ANCAs suna kai hari kan lafiyayyun ƙwayoyin da aka sani da ƙwayoyin cuta (wani nau'in ƙwayoyin farin jini) bisa kuskure. Wannan na iya haifar da rashin lafiya da aka sani da autoimmune vasculitis. Autoimmune vasculitis yana haifar da kumburi da kumburin jijiyoyin jini.

Magungunan jini suna ɗauke da jini daga zuciyar ku zuwa gaɓoɓinku, kayan jikinku, da sauran tsarin, sannan kuma su sake dawowa. Ire-iren jijiyoyin jini sun hada da jijiyoyin jini, jijiyoyi, da kumburi. Infonewa a cikin jijiyoyin jini na iya haifar da mummunar matsalar lafiya. Matsaloli sun bambanta dangane da abin da tasirin jijiyoyin jini da tsarin jiki ke shafar.

Akwai manyan nau'ikan ANCA guda biyu. Kowannensu yana ƙaddamar da takamaiman furotin a cikin ƙwayoyin farin jini:

• pANCA, wanda ke niyyar gina jiki mai suna MPO (myeloperoxidase)
• CANCA, wanda ke niyyar furotin da ake kira PR3 (proteinase 3)

Jarabawar na iya nuna ko kuna da nau'ikan rigakafi ɗaya ko duka biyun. Wannan na iya taimaka wa mai ba da lafiyar ku gano asali da kuma magance cutar ku.

Sauran sunaye: antibodies ANCA, cANCA pANCA, cytoplasmic neutrophil antibodies, magani, antiytoplasmic autoantibodies

Me ake amfani da shi?

Ana amfani da gwajin ANCA mafi yawancin lokuta don gano ko kuna da nau'in cutar vasculitis na autoimmune. Akwai nau'ikan wannan cuta. Dukansu suna haifar da kumburi da kumburin jijiyoyin jini, amma kowane nau'i yana shafar jijiyoyin jini daban-daban da sassan jiki. Ire-iren cututtukan vasculitis na autoimmune sun hada da:

• Granulomatosis tare da polyangiitis (GPA), wanda a baya ake kira cutar Wegener. Mafi yawanci yakan shafi huhu, koda, da sinus.
• Microscopic polyangiitis (MPA). Wannan cuta na iya shafar gabobin jiki da yawa, ciki har da huhu, kodoji, tsarin juyayi, da fata.
• Eosinophilic granulomatosis tare da polyangiitis (EGPA), wanda a baya ake kira ciwon Churg-Strauss. Wannan rikicewar yakan shafi fata da huhu. Yana yawan haifar da asma.
• Polyarteritis nodosa (PAN). Wannan rikicewar ya fi shafar zuciya, koda, fata, da kuma tsarin juyayi na tsakiya.

Hakanan ana iya amfani da gwajin ANCA don saka idanu kan maganin waɗannan rikice-rikice.

Me yasa nake buƙatar gwajin ANCA?

Mai kula da lafiyar ku na iya yin odar gwajin ANCA idan kuna da alamun rashin lafiyar vasculitis. Kwayar cutar sun hada da:

• Zazzaɓi
• Gajiya
• Rage nauyi
• Muscle da / ko haɗin gwiwa

Hakanan cututtukan cututtukanku na iya shafar ɗaya ko mahimman gabobin jikinku. Gabobin da aka fi sani da alamun da suke haifar sun haɗa da:

• Idanu
  • Redness
  • Duban gani
  • Rashin gani
• Kunnuwa
  • Ingara a kunnuwa (tinnitus)
  • Rashin ji
• Sinuses
  • Sinus zafi
  • Hancin hanci
  • Hanci yayi jini
• Fata
  • Rashes
  • Ciwo ko marurai, wani nau'in ciwo mai zurfin da ke saurin warkewa da / ko ci gaba da dawowa
• Huhu
  • Tari
  • Matsalar numfashi
  • Ciwon kirji
• Kodan
  • Jini a cikin fitsari
  • Fitsari mai kumfa, wanda furotin ke haifar da shi
• Jijiya
  • Nutsawa da kaɗawa a sassa daban daban na jiki

Menene ya faru yayin gwajin ANCA?

Kwararren masanin kiwon lafiya zai dauki samfurin jini daga jijiyar hannunka, ta amfani da karamin allura. Bayan an saka allurar, za a tara karamin jini a cikin bututun gwaji ko kwalba. Kuna iya jin ɗan kaɗan lokacin da allurar ta shiga ko fita. Wannan yawanci yakan dauki kasa da minti biyar.

Shin zan bukaci yin komai don shirya wa gwajin?

Ba kwa buƙatar kowane shiri na musamman don gwajin ANCA.

Shin akwai haɗari ga gwajin?

Akwai haɗari kaɗan don yin gwajin jini. Kuna iya samun ɗan ciwo ko rauni a wurin da aka sanya allurar, amma yawancin alamun suna tafi da sauri.

Menene sakamakon yake nufi?

Idan sakamakonka ya kasance mara kyau, yana nufin alamun ku tabbas ba saboda cutar vasculitis ba ne.

Idan sakamakonka tabbatacce ne, yana iya nufin kana da cutar vasculitis na autoimmune. Hakanan zai iya nuna idan an sami cANCAs ko pANCAs. Wannan na iya taimakawa wajen tantance wane irin vasculitis ne kuke da shi.

Ko da wane irin nau'in ƙwayoyin cuta aka samo, kuna iya buƙatar ƙarin gwaji, wanda aka sani da biopsy, don tabbatar da cutar. Biopsy hanya ce da ke cire ƙaramin samfurin nama ko ƙwayoyin halitta don gwaji. Mai kula da lafiyar ka na iya yin oda ƙarin gwaje-gwaje don auna adadin ANCA a cikin jininka.

Idan a halin yanzu ana kula da ku don cutar vasculitis, sakamakonku na iya nuna ko maganinku yana aiki.

Idan kuna da tambayoyi game da sakamakonku, yi magana da mai ba ku kiwon lafiya.

Learnara koyo game da gwaje-gwajen gwaje-gwaje, jeri na tunani, da fahimtar sakamako.

Shin akwai wani abin da nake bukatar sani game da gwajin ANCA?

Idan sakamakon ANCA naka ya nuna kana da cutar vasculitis, akwai hanyoyin magance da kuma kula da yanayin. Magunguna na iya haɗawa da magani, hanyoyin kwantar da hankali waɗanda ke cire ANCAs na ɗan lokaci daga jininka, da / ko tiyata.

Bayani

1. Allina Lafiya [Intanet]. Minneapolis: Allina Lafiya; C-ANCA aunawa; [aka ambata 2019 Mayu 3]; [game da fuska 3]. Akwai daga: https://account.allinahealth.org/library/content/49/150100
2. Allina Lafiya [Intanet]. Minneapolis: Allina Lafiya; P-ANCA aunawa; [aka ambata 2019 Mayu 3]; [game da fuska 3]. Akwai daga: https://account.allinahealth.org/library/content/49/150470
3. Cleveland Clinic [Intanet]. Cleveland (OH): Cleveland Clinic; c2019. Ciwon Kafa da Kafa; [aka ambata 2019 Mayu 3]; [game da fuska 3]. Akwai daga: https://my.clevelandclinic.org/health/diseases/17169-leg-and-foot-ulcers
4. Gwaje-gwajen Lab a kan layi [Intanet]. Washington DC: Associationungiyar (asar Amirka don Magungunan Kiwon Lafiya; c2001–2019. ANCA / MPO / PR3 Kwayoyin cuta; [sabunta 2019 Apr 29; da aka ambata 2019 Mayu 3]; [game da allo 2]. Akwai daga: https://labtestsonline.org/tests/ancampopr3-antibodies
5. Gwaje-gwajen Lab a kan layi [Intanet]. Washington DC: Associationungiyar (asar Amirka don Nazarin Kimiyyar Clinical; c2001–2019. Biopsy; [sabunta 2017 Jul 10; da aka ambata 2019 Mayu 3]; [game da allo 2]. Akwai daga: https://labtestsonline.org/glossary/biopsy
6. Gwaje-gwajen Lab a kan layi [Intanet]. Washington DC: Associationungiyar (asar Amirka don Nazarin Kimiyyar Clinical; c2001–2019. Vasculitis; [sabunta 2017 Sep 8; da aka ambata 2019 Mayu 3]; [game da allo 2]. Akwai daga: https://labtestsonline.org/conditions/vasculitis
7. Mansi IA, Opran A, Rosner F. ANCA-atedungiyar Smallananan-Vessel Vasculitis. Am Fam Likita [Intanet]. 2002 Apr 15 [wanda aka ambata 2019 Mayu 3]; 65 (8): 1615-1621. Akwai daga: https://www.aafp.org/afp/2002/0415/p1615.html
8. Mayo Laboratories Clinic [Internet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1995–2019. Gwajin ID: ANCA: Cytoplasmic Neutrophil Antibodies, magani: Clinical da Fassara; [aka ambata 2019 Mayu 3]; [game da fuska 4]. Akwai daga: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/9441
9. Zuciyar Kasa, Huhu, da Cibiyar Jini [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; Gwajin jini; [aka ambata 2019 Mayu 3]; [game da fuska 3]. Akwai daga: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. Zuciyar Kasa, Huhu, da Cibiyar Jini [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; Vasculitis; [aka ambata 2019 Mayu 3]; [game da allo 2]. Akwai daga: https://www.nhlbi.nih.gov/health-topics/vasculitis
11. Radice A, Sinico RA. Antineutrophil Cytoplasmic Antibodies (ANCA). Autoimmunity [Intanet]. 2005 Feb [wanda aka ambata 2019 Mayu 3]; 38 (1): 93–103. Akwai daga: https://www.ncbi.nlm.nih.gov/pubmed/15804710
12. Cibiyar Kidney ta UNC [Intanet]. Chapel Hill (NC): Cibiyar Koda ta UNC; c2019. ANCA Vasculitis; [sabunta 2018 Sep; da aka ambata 2019 Mayu 3]; [game da fuska 3]. Akwai daga: https://unckidneycenter.org/kidneyhealthlibrary/glomerular-disease/anca-vasculitis

Ba za a yi amfani da bayanan da ke wannan rukunin yanar gizon a madadin madadin ƙwararrun likitocin ko shawara ba. Tuntuɓi mai ba da kiwon lafiya idan kuna da tambayoyi game da lafiyarku.