Soliqua 100/33 (insulin glargine / lixisenatide)

Wadatacce

• Menene Soliqua 100/33?
• Inganci
• Soliqua 100/33 na asali
• Soliqua 100/33 sashi
• Magungunan ƙwayoyi da ƙarfi
• Sashi don Soliqua 100/33
• Menene idan na rasa kashi?
• Shin zan buƙaci amfani da wannan magani na dogon lokaci?
• Soliqua 100/33 sakamako masu illa
• Commonarin sakamako masu illa na kowa
• M sakamako mai tsanani
• Soliqua 100/33 farashin
• Taimakon kuɗi da inshora
• Yadda ake shan Soliqua 100/33
• Yadda ake gudanarwa
• Lokaci
• Shan Soliqua 100/33 tare da abinci
• Madadin Soliqua 100/33
• Soliqua 100/33 vs. Xultophy
• Yana amfani da
• Magungunan ƙwayoyi da gudanarwa
• Sakamakon sakamako da kasada
• Inganci
• Kudin
• Soliqua 100/33 vs. wasu magunguna
• Soliqua 100/33 vs. Lantus
• Soliqua 100/33 vs. Victoza
• Soliqua 100/33 vs. Toujeo
• Soliqua 100/33 vs. Adlyxin
• Soliqua 100/33 amfani
• Soliqua 100/33 amfani tare da wasu magunguna
• Soliqua 100/33 da barasa
• Soliqua 100/33 ma'amala
• Soliqua 100/33 da sauran magunguna
• Soliqua 100/33 da ganye da kari
• Yadda Soliqua 100/33 yake aiki
• Ta yaya insulin ke shafar sukarin jini
• Abin da Soliqua 100/33 yake yi
• Yaya tsawon lokacin aiki?
• Soliqua 100/33 da ciki
• Soliqua 100/33 da nono
• Tambayoyi gama gari game da Soliqua 100/33
• Shin Soliqua 100/33 yana haifar da karin nauyi?
• Shin Soliqua 100/33 insulin ne?
• Shin Soliqua 100/33 yana da dogon lokaci?
• Shin ana iya amfani da Soliqua 100/33 don magance ciwon sukari na 1?
• Gargadin Soliqua 100/33
• Soliqua 100/33 yawan abin da ya kamata
• Symptomsara yawan ƙwayoyi
• Abin da za a yi idan ya wuce gona da iri
• Soliqua 100/33 karewa da ajiya
• Bayani na ƙwararru don Soliqua 100/33
• Manuniya
• Hanyar aiwatarwa
• Pharmacokinetics da metabolism
• Contraindications
• Ma'aji

Menene Soliqua 100/33?

Soliqua 100/33 magani ne mai ɗauke da suna. Ana amfani da shi tare da abinci da motsa jiki don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2.

Soliqua 100/33 ya ƙunshi kwayoyi biyu:

• insulin glargine, wanda shine insulin mai aiki tsawon lokaci
• lixisenatide, wanda ke cikin rukunin magungunan da ake kira masu kamuwa da agonists masu kama da peptide 1 (GLP-1)

Soliqua 100/33 ya zo azaman alkalami mai allura wanda ake amfani da shi don allurar kai tsaye a ƙarƙashin fata (subcutaneous). Kowane alkalami yana dauke da 3 mL na maganin magani, tare da raka'a 100 na insulin glargine da 33 mcg na lixisenatide a kowace mL na bayani. Ana amfani da alkalama tare da allurar alkalami, waɗanda ba a haɗa su da alƙalami ba.

Inganci

Soliqua 100/33 an gano yana da tasiri wajen magance ciwon siga na 2. A cikin wani binciken asibiti, an gwada Soliqua 100/33 a cikin mutanen da ke da ciwon sukari na 2 waɗanda aka ba su magani na dogon lokaci na ɓatancin watanni shida. Bayan makonni 30 na magani tare da Soliqua 100/33, waɗannan mutanen sun rage haemoglobin A1c (HbA1c) da kashi 1.1. Hakanan sun rage matakan sukarin jini na azumi da 5.7 mg / dL.

A wani binciken asibiti, an yi amfani da Soliqua 100/33 tare da metformin tsawon makonni 30. Binciken ya shafi mutanen da a baya aka ba su magani tare da metformin shi kaɗai, ko kuma tare da metformin da kuma wani maganin ciwon sukari na baka. Jiyya tare da Soliqua 100/33 da metformin sun rage HbA1c da kashi 1.6. Hakanan ya rage matakan sukarin jini na azumi da 59.1 mg / dL.

Soliqua 100/33 na asali

Soliqua 100/33 yana samuwa ne kawai azaman magani mai suna. Babu shi a halin yanzu a cikin sifa iri.

Soliqua 100/33 yana dauke da kwayoyi biyu masu aiki: insulin glargine da lixisenatide. Babu magani a cikin sifa iri ɗaya.

Insulin glargine insulin ne mai aiki mai tsayi wanda ake samunsa a kashin kansa azaman magunguna iri-iri irin su Lantus, Toujeo, da Basaglar. Lixisenatide na cikin nau'ikan magungunan da ake kira agcists-like peptide 1 (GLP-1) na masu karɓa. Ana samuwa azaman samfurin-mai suna Adlyxin.

Soliqua 100/33 sashi

Yawanci, likitanka zai fara maka akan ƙananan Soliqua 100/33 kuma daidaita shi akan lokaci don isa sashin da ya dace maka. Wannan tsarin daidaitawa ana kiran sa titration. Likitanku a ƙarshe zai tsara ƙaramin sashi wanda ke ba da tasirin da ake so.

Bayani mai zuwa yana bayanin abubuwan da ake amfani dasu ko aka ba da shawarar. Koyaya, tabbatar da shan maganin da likitanka yayi maka. Likitan ku zai ƙayyade mafi kyawun sashi don dacewa da bukatun ku.

Magungunan ƙwayoyi da ƙarfi

Kowane kunshin Soliqua 100/33 yana dauke da yarwa guda biyar, preoli mai cike Soliqua 100/33 allurar allura a kowane akwati. Ba a haɗa allurar alkalami tare da alkalama ba. (A mafi yawan lokuta, zaku iya siyan allurar alkalami a kantin magani. Kuna iya buƙatar takardar sayan magani.)

Kowane alkalami na allura yana ƙunshe da 3 mL na maganin magani, tare da jimlar raka'a 300 na insulin glargine da 100 mcg na lixisenatide.

Aljihunan allurar Soliqua 100/33 kowannensu ana nufin amfani dashi sau da yawa. Yawan lokuta na iya zuwa daga 5 zuwa 20 sau, dangane da sashi. Ana iya amfani da kowane alkalami na tsawon kwanaki 28 bayan amfanin farko. Bayan wannan lokacin, ya kamata ku zubar da alkalami, koda kuwa har yanzu yana dauke da wasu magungunan.

Dole ne a yi amfani da allurar alkalami sau ɗaya kawai kowanne.

Sashi don Soliqua 100/33

Soliqua 100/33 yawanci an tsara shi a cikin allurai guda 15 zuwa raka'a 60 kowane. Kalmar "raka'a" ita ce nau'in aunawa wanda aka yi amfani da shi don insulin glargine da ke cikin Soliqua 100/33. Matsakaicin matsakaici a kowace allura ita ce raka'a 60, wanda ke nufin raka'a 60 na insulin glargine da 20 mcg lixisenatide.

Fara sashi

Abun shawarar farawa na Soliqua 100/33 ya dogara da maganin ciwon suga na baya.

Lura: Kafin fara Soliqua 100/33, ya kamata ka dakatar da duk wani maganin tare da lixzenatide ko insulin mai dadewa.

Sashi mai kulawa

Bayan fara Soliqua 100/33, likitanku zai kula da matakan sukarin jininku kuma zai iya daidaita saitinku don isa adadin ku daidai. Maƙerin maganin ya ba da shawarar karkatar da kashi sama ko ƙasa ta raka'a 2 zuwa 4 kowane mako kamar yadda ake buƙata don cimma burin sukarin jini.

Kashi gyara

Ku da likitanku za ku yi aiki tare don ƙirƙirar wani shiri don saduwa da burin jini na jini.

Da ke ƙasa akwai misali na daidaitattun ƙoshin likitanku na iya ba da shawarar. Likitanku zai yanke shawara idan kuna buƙatar waɗannan gyare-gyaren. Tabbatar shan kashi wanda likitanka ya ba da shawarar. (Kada ku canza yawan ku ba tare da amincewar likitan ku ba.)

Menene idan na rasa kashi?

Idan ka rasa kashi na Soliqua 100/33, ka tsallake wannan maganin ka ci gaba da tsarin da zaka tsara na gaba. Kada kayi ƙoƙarin kamawa ta hanyar shan ƙarin kashi ko ƙara kashi na gaba. Wannan na iya haifar da illa mai illa.

Shin zan buƙaci amfani da wannan magani na dogon lokaci?

Idan Soliqua 100/33 yana da tasiri kuma mai aminci a gare ku, tabbas zaku iya amfani da wannan maganin na dogon lokaci. Soliqua 100/33 yawanci ana amfani dashi tsawon lokaci don magance ciwon sukari na 2.

Soliqua 100/33 sakamako masu illa

Soliqua 100/33 na iya haifar da lahani ko mummunan sakamako. Jerin na gaba yana ƙunshe da wasu mahimman abubuwan illa da zasu iya faruwa yayin shan Soliqua 100/33. Wannan jerin ba ya haɗa da duk illa mai yuwuwa.

Don ƙarin bayani game da yuwuwar illa na Soliqua 100/33, ko nasihu kan yadda za'a magance matsalar illa, yi magana da likitanka ko likitan magunguna.

Commonarin sakamako masu illa na kowa

Abubuwan da suka fi dacewa na Soliqua 100/33 na iya haɗawa da:

• tashin zuciya
• cututtukan da suka shafi numfashi irin su sanyi ko mura
• gudawa
• ciwon kai
• hypoglycemia (ƙarancin sukarin jini)

Yawancin waɗannan tasirin na iya wucewa cikin withinan kwanaki kaɗan ko makonni kaɗan. Idan sun fi tsanani ko kuma basu tafi ba, yi magana da likitanka ko likitan magunguna.

M sakamako mai tsanani

M sakamako masu illa daga Soliqua 100/33 ba su da yawa, amma suna iya faruwa. Kira likitanku nan da nan idan kuna da mummunar illa. Kira 911 idan alamunku suna jin barazanar rai ko kuma idan kuna tunanin kuna samun gaggawa na likita.

M sakamako masu illa da alamomin su na iya haɗawa da masu zuwa:

• Mai tsananin rashin lafiyan dauki. Kwayar cutar na iya haɗawa da:
• kurji
• wankewa
• kumburi
• fata mai ƙaiƙayi
• matsalar numfashi
• saukar karfin jini
• Pancreatitis (kumburi na pancreas). Kwayar cutar na iya haɗawa da:
• zafi ko taushi a cikin ciki
• ciwon baya
• tashin zuciya
• amai
• zazzaɓi
• asarar nauyi
• Lalacewar koda. Kwayar cutar na iya haɗawa da:
• rage fitsari
• kumburi a ƙafafunku, idon sawu, ko ƙafa
• rikicewa
• gajiya
• tashin zuciya
• ciwon kirji ko matsi
• bugun zuciya mara tsari
• kamuwa
• Hypokalemia (low potassium). Kwayar cutar na iya haɗawa da:
• rauni
• gajiya
• maƙarƙashiya
• Ciwan tsoka
• bugun zuciya mara tsari

Rage nauyi ko rage nauyi

A cikin gwaji na asibiti, ba a sami Soliqua 100/33 don haifar da canjin nauyi ba. Koyaya, a cikin binciken asibiti ɗaya, mutanen da suka ɗauki Soliqua 100/33 tsawon makonni 30 sun yi asarar kusan fam 1.5.

Bugu da kari, kowane mutum kwayoyi da ke cikin Soliqua 100/33 an danganta su da canjin nauyi. Soliqua 100/33 yana dauke da insulin glargine, insulin mai dadewa. Magungunan da ke dauke da insulin na iya haifar da karin nauyi.

Soliqua 100/33 shima yana dauke da lixisenatide, mai kama da peptide 1 (GLP-1) agonist. A cikin karatun asibiti daban-daban, magunguna a cikin rukunin magani na GLP-1 sun nuna asarar nauyi a matsayin sakamako mai illa.

Idan kun damu game da canjin nauyi yayin amfani da Soliqua 100/33, yi magana da likitanku.

Hypoglycemia

Ana amfani da insulin, daya daga cikin magunguna a cikin Soliqua 100/33, don taimakawa rage matakan sukarin jini. Koyaya, ana iya saukar da matakan sukarin jini sosai, wanda ke haifar da hypoglycemia. Hypoglycemia shine sakamako mafi illa na yau da kullun wanda magungunan insulin ke haifarwa, gami da Soliqua 100/33.

A cikin karatun asibiti, hypoglycemia ya faru a cikin 8.1 zuwa kashi 17.8 na mutanen da ke shan Soliqua 100/33. Kuma mummunan hypoglycemia ya faru a kusan kashi 1 na mutanen da ke shan magani.

Yawancin dalilai na iya haɓaka haɗarin hypoglycemia. Waɗannan sun haɗa da shan ƙwayoyi masu yawa na magungunan ciwon sukari da shan fiye da ɗaya magani na ciwon sukari. Sauran abubuwan da zasu iya shafar haɗarinku sun haɗa da cin abincinku da halayen motsa jiki, da kuma ko kuna shan wasu magunguna.

Kwayar cututtukan hypoglycemia na iya faruwa farat ɗaya kuma suna iya haɗawa da rashi, gajiya, bacci, da rikicewa. Tsananin hypoglycemia na iya haifar da mummunan sakamako kamar haɗari ko ma mutuwa. Yi magana da likitanka game da sau nawa ya kamata ka duba matakan sikarin jininka don hana hypoglycemia yayin shan Soliqua 100/33.

Bacin rai ko kaurin fata

Kuna shan Soliqua 100/33 ta hanyar allurar subcutaneous, wanda ke nufin kuyi masa allurar a karkashin fata. Allurar ƙwayar cuta a ƙarƙashin fata na iya haifar da lipodystrophy (ɓacin rai ko kaurin fata) a kewayen wurin allurar.

Don rage haɗarin cutar lipodystrophy, maye gurbin rukunin yanar gizo inda kuke yin allurar ƙwayoyi. Misali, wata rana zaka iya yin allurar maganin a cikinka, sannan na gaba zaka iya amfani da cinya ta waje.

Idan kun damu game da tasirin fata sanadiyyar allurar Soliqua 100/33, yi magana da likitanka.

Lalacewar koda

Ba a ga lalacewar koda ba a cikin nazarin asibiti na Soliqua 100/33. Koyaya, akwai rahotanni game da lalacewar koda a cikin mutanen da aka bi da su tare da magunguna na pecide 1 (GLP-1) na glucagon. Lixisenatide, wanda shine ɗayan magunguna a Soliqua 100/33, magani ne na GLP-1.

Kwayar cututtukan cututtukan koda na iya haɗawa da:

• kumburi na ƙafa, idon kafa, ko ƙafa
• gajiya
• tashin zuciya
• amai

Lalacewar koda galibi yana faruwa ne ga mutanen da suka kamu da ruwa saboda wasu illoli na Soliqua 100/33, kamar jiri, amai, da gudawa.

Idan ka ci gaba da waɗannan alamun yayin shan Soliqua 100/33, ko kuma ka damu da lafiyar koda, yi magana da likitanka.

Soliqua 100/33 farashin

Kamar yadda yake tare da duk magunguna, farashin Soliqua 100/33 na iya bambanta.

Kudin ku na ainihi zai dogara ne akan inshorar ku.

Taimakon kuɗi da inshora

Idan kuna buƙatar tallafin kuɗi don biyan Soliqua 100/33, akwai taimako. Sanofi Aventis, mai ƙera Soliqua 100/33, yana ba da Soliqua 100/33 Katin Adanawa. Don ƙarin bayani, ziyarci gidan yanar gizon shirin.

Yadda ake shan Soliqua 100/33

Da ke ƙasa akwai wasu umarni na asali kan yadda zaka yiwa kanka allura ta amfani da alkalami Soliqua 100/33. Koyaushe ka tabbata ka ɗauki Soliqua 100/33 bisa ga umarnin likitanka ko mai ba da kiwon lafiya.

Yadda ake gudanarwa

Mataki 1. Shirya ka duba alƙalaminka.

Idan wannan shine amfanin ka na farko, cire alkalami daga firiji ka barshi alkalami ya kai ga zafin dakin.

• Tattara kayan maye, sabon allura, da kuma kwandon shara.
• Wanke hannuwanka.
• Cire kafin alkalami ka tabbatar maganin ya bayyana kuma bashi da launi. (Kar a yi amfani da shi idan maganin bai bayyana ba kuma ba shi da launi. Kumfar iska suna lafiya.)
• Tsaftace hatimin roba tare da sandar barasa.

Mataki 2. Haɗa sabon allurar alkalami.

Ga kowane allura, koyaushe yi amfani da sabon allurar alkalami. Tabbatar cewa ana iya amfani da allurar alkalami tare da Soliqua 100/33. Idan baku san ko allurar da zaku yi amfani da ita ba, tambayi likitan ku ko likitan magunguna.

• Cire allurar alkalami daga kunshin kariya.
• Tsayawa allurar alkalami ta miƙe, murɗe ta a kan alƙalamin.
• Cire murfin allurar alkalami na waje ka ajiye shi gefe. (Rike shi don amfani bayan allurar.)
• Cire murfin allura na ciki ka yar dashi cikin kwandon shara.

Mataki na 3. Yi gwajin lafiya.

Koyaushe kayi gwajin lafiya kafin kowane allura don tabbatar alƙalami da allura suna aiki daidai.

• Daidaita ma'aunin maganin domin ya karanta raka'a 2.
• Latsa maɓallin allurar gabaɗaya kuma bincika ɗan maganin magani don fitowa daga ƙirar allurar. Idan wannan ya faru, ci gaba zuwa mataki na 4.
• Idan babu magani ya fito, maimaita gwajin lafiya har sau 3.
• Idan babu magani ya fito bayan gwaje-gwaje uku, maye gurbin allurar kuma maimaita gwaje-gwajen amincin.
• Idan babu wani magani da ya fito bayan maye gurbin allurar, kar a yi amfani da alƙalami domin yana iya lalacewa. Yi amfani da sabon alkalami.

Mataki 4. Zaɓi yawan ku.

• Juya maganin har sai kun isa kasuwarku.

Mataki 5. Allurar allurai.

Akwai yankuna uku a jikinka da zaka iya amfani dasu don wurin allura: cikinka (banda tsakanin inci 2 daga maɓallin cikinka), da bayan hannun hannunka na sama (yankin mai mai), da cinyar ka ta waje.

• Zaɓi wurin allura ka goge fatar a wurin da abin maye.
• A wurin allurar, saka allurar a cikin fatarka a kusurwa 90-degree.
• Latsa maɓallin allurar ƙasa gaba ɗaya kuma riƙe shi har sai kun ga “0” a cikin taga taga.
• Bayan da abin juyawar ya juya zuwa “0,” a kirga zuwa 10 kafin sakin maɓallin allurar da cire allurar. Wannan ɗan dakatarwar yana taimaka tabbatar da cewa kun sami cikakken adadin.
• Saki maɓallin allurar kuma cire allurar daga fata.

Mataki 6. Yi watsi da allurar kuma adana alƙalamin.

• Sanya murfin allurar alkalami na baya akan allurar.
• Cire allurar daga alurar allurar kuma nan da nan zubar da allura a cikin wani sharps ganga. (A jefar dashi yanzunnan don kaucewa rikita shi da sabon allura.)
• Sanya hular alkalami kan alkalami.
• Ajiye alkalami a ɗakin zafin jiki bayan amfanin farko.

Lokaci

Ya kamata ku ɗauki Soliqua 100/33 a cikin sa'a kafin abincinku na farko na ranar.

Shan Soliqua 100/33 tare da abinci

Kada a dauki Soliqua 100/33 da abinci. Ya kamata a sha tsakanin sa'a kafin cin abincinku na farko na rana.

Madadin Soliqua 100/33

Akwai wasu kwayoyi waɗanda zasu iya magance ciwon sukari na 2. Wasu na iya zama sun fi dacewa da kai fiye da wasu. Idan kuna sha'awar neman madadin Soliqua 100/33, yi magana da likitan ku don ƙarin koyo game da wasu magunguna waɗanda zasu iya muku aiki da kyau.

Soliqua 100/33 yana dauke da kwayoyi biyu: insulin mai dadewa wanda ake kira insulin glargine, da kuma agonist mai kama da peptide 1 (GLP-1) mai suna gluisagon wanda ake kira lixisenatide.

Misalan magunguna waɗanda za a iya amfani da su azaman madadin Soliqua 100/33 sun haɗa da:

• insulin na dogon lokaci, kamar:
• insulin glargine (Lantus, Toujeo)
• insulin detemir (Levemir)
• GLP-1 agonists masu karɓa, kamar:
• ƙari (Bydureon, Byetta)
• liraglutide (Victoza, Saxenda)
• lixisenatide (Adlyxin)
• semaglutide (Ozempic)
• dipeptidyl peptidase-4 (DPP-4) masu hanawa, kamar su:
• alogliptin (Nesina)
• linagliptin (Tradjenta)
• saxagliptin (Onglyza)
• sitagliptin (Januvia)
• meglitinides, kamar su:
• maimaitawa (Prandin)
• nateglinide (Starlix)
• metformin (Glucophage, Glumetza, Ruwan kwalliya)
• sodium-glucose cotransporter 2 (SGLT2) masu hanawa, kamar su:
• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• sulfonylureas, kamar su:
• gillypiride (Amaryl)
• gipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• thiazolidinediones, kamar:
• pioglitazone (Actos)
• rosiglitazone (Avandia)

Soliqua 100/33 vs. Xultophy

Kuna iya mamakin yadda Soliqua 100/33 yake kwatanta da sauran magunguna waɗanda aka tsara don amfani iri ɗaya.Anan zamu kalli yadda Soliqua 100/33 da Xultophy suke da kuma banbanci.

Yana amfani da

Soliqua 100/33 da Xultophy duka an amince da FDA don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2. An tsara su duka don amfani tare da canjin abinci da motsa jiki.

Soliqua 100/33 da Xultophy duk suna ɗauke da kwayoyi biyu, kuma waɗannan magungunan suna cikin ajin magunguna iri ɗaya. Wannan yana nufin suna aiki iri ɗaya a cikin jiki.

Soliqua 100/33 ya ƙunshi:

• insulin glargine (insulin mai dogon lokaci)
• lixisenatide (mai kama da peptide 1 [GLP-1] agonist)

Xultophy ya ƙunshi:

• insulin degludec (insulin mai dogon lokaci)
• liraglutide (GLP-1 agonist mai karɓa)

Magungunan ƙwayoyi da gudanarwa

Soliqua 100/33 da Xultophy duka sun zo azaman maganin ruwa ne a cikin alƙalamin allurar da za a yarwa. Dukansu allurar kai tsaye ne a ƙarƙashin fata (subcutaneous) sau ɗaya a rana.

Sakamakon sakamako da kasada

Soliqua 100/33 da Xultophy suna da irin wannan tasirin a cikin jiki kuma saboda haka suna haifar da sakamako mai kama da juna.

Commonarin sakamako masu illa na kowa

Wannan jeri ya ƙunshi misalai na cututtukan cututtukan da suka fi dacewa waɗanda zasu iya faruwa tare da magungunan biyu (lokacin ɗauka daban-daban)

• Zai iya faruwa tare da duka Soliqua 100/33 da Xultophy:
• cututtukan da suka shafi numfashi irin su sanyi ko mura
• tashin zuciya
• gudawa
• ciwon kai
• hypoglycemia (ƙarancin sukarin jini)

M sakamako mai tsanani

Waɗannan jerin suna ƙunshe da misalai na larura masu haɗari waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Xultophy, ko tare da magungunan duka biyu (lokacin ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
• uniquean ƙananan sakamako masu illa na musamman
• Zai iya faruwa tare da Xultophy:
• ciwon sankarar kansa *
• gallbladder cuta
• Zai iya faruwa tare da duka Soliqua 100/33 da Xultophy:
• mai tsanani rashin lafiyan dauki
• mummunan hypoglycemia (mai tsananin ƙarancin jini)
• pancreatitis (kumburi na pancreas)
• lalacewar koda
• hypokalemia (ƙananan matakan potassium)

* Xultophy yana da gargaɗin dambe daga FDA don cutar kansa. Gargadi mai ban tsoro shine gargadi mafi karfi da FDA ke buƙata. Yana faɗakar da likitoci da marasa lafiya game da tasirin kwayoyi waɗanda zasu iya zama haɗari.

Inganci

Ba a kwatanta Soliqua 100/33 da Xultophy kai tsaye a cikin karatun asibiti ba, amma duka an same su da inganci don magance ciwon sukari na 2.

A cikin karatun daban, Soliqua 100/33 da Xultophy duka suna da tasiri wajen rage HbA1c da kuma saurin sukarin jini.

• A cikin binciken asibiti, Soliqua 100/33 ya rage haemoglobin A1c (HbA1c) da kashi 1.1 kuma ya yi sauri da saurin sukarin jini da 5.7 mg / dL bayan makonni 30 na magani.
• A cikin karatun asibiti, Xultophy ya rage HbA1c da kashi 1.31 zuwa kashi 1.94 da kuma saurin sukarin jini ta 49.9 mg / dL zuwa 63.5 mg / dL bayan makonni 26 na magani. Mutanen da ke amfani da Xultophy suma sun sami kusan fam 4.4 sama da makonni 26 na jiyya.

Lura: Yana da mahimmanci a tuna cewa yadda ɗayan waɗannan ƙwayoyin zasu rage HbA1c ɗinka ko matakan sikarin jini zai dogara da dalilai da yawa, gami da:

• matakan jinin ku lokacin da kuka fara magani
• tsarin abincinku da tsarin motsa jiki
• sauran magungunan ciwon suga da kuke sha
• yadda kake bin tsarin kulawa da kai

Kudin

Soliqua 100/33 da Xultophy duka magunguna ne masu alamar iri. A halin yanzu babu nau'ikan sifofin da ake samu na ko dai magunguna. Magungunan sunaye suna yawanci suna da tsada fiye da na zamani.

Dangane da ƙididdiga daga GoodRx.com, Xultophy na iya cin kuɗi fiye da Soliqua 100/33. Ainihin farashin da zaku biya don ko dai magani zai dogara ne akan adadin ku, shirin inshorar ku, wurin ku, da kuma kantin da kuke amfani dashi.

Soliqua 100/33 vs. wasu magunguna

Akwai wasu magunguna banda Soliqua 100/33 da Xultophy (na sama) waɗanda za a iya amfani da su don magance ciwon sukari na nau'in 2. Da ke ƙasa akwai kwatancen tsakanin Soliqua 100/33 da wasu magunguna da yawa.

Soliqua 100/33 vs. Lantus

Soliqua 100/33 ya ƙunshi kwayoyi biyu:

• insulin glargine, wanda shine insulin mai aiki tsawon lokaci
• lixisenatide, wanda ke cikin rukunin magungunan da ake kira masu kamuwa da agonists masu kama da peptide 1 (GLP-1)

Insulin glargine shine maganin da ke cikin Lantus. Saboda Soliqua 100/33 da Lantus suna aiki tare, suna aiki iri ɗaya a cikin jiki.

Yana amfani da

Soliqua 100/33 an yarda da FDA don amfani tare da canjin abinci da motsa jiki don inganta matakan sukarin jini a cikin manya da ciwon sukari na 2.

Lantus an yarda da FDA don inganta matakan sukarin jini a cikin manya da yara waɗanda ke da ciwon sukari na 1, da kuma manya da ciwon sukari na 2.

Magungunan ƙwayoyi da gudanarwa

Soliqua 100/33 ya zo azaman bayani na ruwa a cikin alƙalamin allurar yarwa. Lantus yana zuwa azaman maganin ruwa a cikin kwalba mai ɗimbin yawa ko a cikin alƙalamin allura wanda za'a iya yarwa. Dukansu magungunan suna yin allurar kai tsaye a ƙarƙashin fata (subcutaneous) sau ɗaya a rana.

Sakamakon sakamako da kasada

Soliqua 100/33 da Lantus duk suna dauke da insulin mai aiki na lokaci daya, glargine na insulin. Sabili da haka, magungunan biyu na iya haifar da sakamako mai kama da juna. Da ke ƙasa akwai misalai na waɗannan tasirin.

Commonarin sakamako masu illa na kowa

Wadannan jerin suna dauke da misalai na cututtukan da suka fi dacewa wadanda zasu iya faruwa tare da Soliqua 100/33, tare da Lantus, ko kuma tare da magungunan biyu (lokacin da aka ɗauka ɗayansu).

• Zai iya faruwa tare da Soliqua 100/33:
  • tashin zuciya
  • cututtukan da suka shafi numfashi irin su sanyi ko mura
  • ciwon kai
  • gudawa
• Zai iya faruwa tare da Lantus:
  • riba mai nauyi
  • lipodystrophy (rashin nutsuwa ko kaurin fata a wurin allura)
  • allurar shafin halayen
• Zai iya faruwa tare da duka Soliqua 100/33 da Lantus:
  • hypoglycemia (ƙarancin sukarin jini)

M sakamako mai tsanani

Waɗannan jerin suna ƙunshe da misalai na larura masu haɗari waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Lantus, ko tare da magungunan duka biyu (lokacin ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
  • pancreatitis (kumburi na pancreas)
  • lalacewar koda
• Zai iya faruwa tare da Lantus:
  • uniquean ƙananan sakamako masu illa na musamman
• Zai iya faruwa tare da duka Soliqua 100/33 da Lantus:
  • mai tsanani rashin lafiyan dauki
  • tsananin hypoglycemia (mai saurin sukari a cikin jini)
  • ƙananan matakan potassium (hypokalemia)

Inganci

An kwatanta tasirin Soliqua 100/33 da Lantus kai tsaye a cikin karatu biyu. A cikin binciken farko, an yi amfani da kwayoyi biyu kowannensu shi kaɗai. A na biyu, an yi amfani da kowannensu a haɗe tare da metformin (maganin ciwon sukari na baka).

Yi amfani da shi kadai

Nazarin farko ya maida hankali ne kan manya da ke dauke da ciwon sukari na 2 wadanda a da aka yi musu magani a baya da insulins mai dogon lokaci. Ya nuna cewa Soliqua 100/33 na iya aiki da kyau fiye da Lantus don rage haemoglobin A1c (HbA1c), amma ba haka ba wajen rage matakan sukarin jini cikin sauri.

Bayan makonni 30 na jiyya, Soliqua 100/33 ya rage HbA1c da kashi 1.1, kuma yana saurin matakan sukarin jini da 5.7 mg / dL. A daidai wannan lokacin, Lantus ya rage HbA1c da kashi 0.6, kuma yana yin saurin sukarin jini da 7.0 mg / dL.

Yi amfani da metformin

Nazarin na biyu ya gwada Soliqua 100/33 tare da metformin akan Lantus tare da metformin a cikin manya masu fama da ciwon sukari na 2. Wadannan mutane sun kasance a baya an yi musu magani tare da metformin kadai, ko kuma tare da metformin da kuma wani maganin ciwon sukari na baka.

Sama da makonni 30, Soliqua 100/33 tare da metformin ya ɗan sami inganci fiye da Lantus tare da metformin. Soliqua 100/33 tare da metformin ya rage HbA1c da kashi 1.6 da kuma saurin sukarin jini da 59.1 mg / dL. Lantus da metformin, a gefe guda, sun rage HbA1c da kashi 1.3 da kuma saurin sukarin jini da ya ragu da 55.8 mg / dL.

Lura: Yana da mahimmanci a tuna cewa yadda ɗayan waɗannan ƙwayoyin zasu rage HbA1c ɗinka ko matakan sikarin jini zai dogara da dalilai da yawa, gami da:

• matakan sukarin jininka lokacin da ka fara magani
• tsarin abincinku da tsarin motsa jiki
• sauran magungunan ciwon suga da kuke sha
• yadda kuke bin tsarin kulawa

Kudin

Soliqua 100/33 da Lantus duka magunguna ne masu alamar iri. A halin yanzu babu nau'ikan sifofin da ake samu na ko dai magunguna. Magungunan sunaye suna yawanci suna da tsada fiye da na zamani.

Dangane da ƙididdiga daga GoodRx.com, Lantus gabaɗaya farashinsa baikai Soliqua 100/33 ba. Gaskiyar farashin da za ku biya don ko dai magani zai dogara ne akan adadin ku, shirin inshorar ku, wurin ku, da kuma kantin da kuke amfani da shi.

Soliqua 100/33 vs. Victoza

Soliqua 100/33 ya ƙunshi kwayoyi biyu:

• insulin glargine, wanda shine insulin mai aiki tsawon lokaci
• lixisenatide, wanda ke cikin rukunin magungunan da ake kira masu kamuwa da agonists masu kama da peptide 1 (GLP-1)

Victoza ya ƙunshi liraglutide na magani, wanda kuma shine agonist mai karɓar GLP-1. Saboda Soliqua 100/33 da Victoza suna aiki tare a ɓangaren magunguna iri ɗaya, suna aiki iri ɗaya a cikin jiki.

Yana amfani da

Soliqua 100/33 an yarda da FDA don inganta matakan sikarin jini a cikin manya da ciwon sukari na 2. An tsara shi don amfani tare da canjin abinci da motsa jiki.

Victoza kuma an yarda da shi don inganta matakan sikarin jini a cikin manya masu ciwon sukari na 2 a haɗe tare da ingantaccen abinci da motsa jiki. Bugu da ƙari, an yarda da shi don rage haɗarin manyan matsalolin zuciya kamar ciwon zuciya da bugun jini a cikin mutanen da ke da ciwon sukari na 2 da cututtukan zuciya.

Magungunan ƙwayoyi da gudanarwa

Dukansu Soliqua 100/33 da Victoza sunzo azaman maganin ruwa ne a cikin alƙalamin allura wanda za'a iya yarwa. Dukansu magungunan suna yin allurar kai tsaye a ƙarƙashin fata (subcutaneous) sau ɗaya a rana.

Sakamakon sakamako da kasada

Saboda Soliqua 100/33 da Victoza duk suna ɗauke da wani magani wanda yake na ajin magani na GLP-1, duka magungunan suna iya haifar da irin wannan tasirin. Da ke ƙasa akwai misalai na waɗannan tasirin.

Commonarin sakamako masu illa na kowa

Wadannan jerin suna dauke da misalai na cututtukan cututtukan da suka fi dacewa wanda zai iya faruwa tare da Soliqua 100/33, tare da Victoza, ko tare da magungunan biyu (lokacin da aka ɗauka ɗayansu).

• Zai iya faruwa tare da Soliqua 100/33:
  • hypoglycemia (ƙarancin sukarin jini)
  • cututtukan da suka shafi numfashi irin su sanyi ko mura
  • ciwon kai
• Zai iya faruwa tare da Victoza:
  • rage yawan ci
  • amai
  • maƙarƙashiya
  • ciki ciki
• Zai iya faruwa tare da duka Soliqua 100/33 da Victoza:
  • tashin zuciya
  • gudawa

M sakamako mai tsanani

Waɗannan jerin suna ƙunshe da misalai na larura masu haɗari waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Victoza, ko tare da magungunan duka biyu (lokacin ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
  • hypokalemia (ƙananan matakan potassium)
• Zai iya faruwa tare da Victoza:
  • ciwon sankarar kansa *
  • gallbladder cuta
• Zai iya faruwa tare da duka Soliqua 100/33 da Victoza:
  • mai tsanani rashin lafiyan dauki
  • tsananin hypoglycemia (mai saurin sukari a cikin jini)
  • pancreatitis (kumburi na pancreas)
  • lalacewar koda

* Victoza tana da gargaɗin dambe daga FDA don cutar kansa. Gargadi mai ban tsoro shine gargadi mafi karfi da FDA ke buƙata. Yana faɗakar da likitoci da marasa lafiya game da tasirin kwayoyi waɗanda zasu iya zama haɗari.

Inganci

Ba a kwatanta Soliqua 100/33 da Victoza kai tsaye a cikin karatun asibiti ba, amma duka an same su da inganci don magance ciwon sukari na 2.

A cikin karatun daban, duka Soliqua 100/33 da Victoza sun saukar da HbA1c da saurin matakan sukarin jini a cikin mutanen da ke da ciwon sukari na 2.

• A cikin binciken asibiti, bayan makonni 30 na jiyya, Soliqua 100/33 ya rage haemoglobin A1c (HbA1c) da kashi 1.1 cikin ɗari kuma ya yi azumi matakan sukarin jini da 5.7 mg / dL.
• A wasu nazarin na asibiti, sama da makonni 52 na jiyya, Victoza ya rage HbA1c da kimanin kashi 0.8 zuwa 1.1 da kuma saurin sukarin jini da 15 zuwa 26 mg / dL.

Wani bincike na asibiti daban ya nuna cewa Victoza ya rage haɗarin manyan matsalolin zuciya kamar su ciwon zuciya da bugun jini da kashi 13 cikin ɗari. Ba a yi nazarin wannan sakamakon ba a cikin bincike akan Soliqua 100/33.

Lura: Yana da mahimmanci a tuna cewa yadda ɗayan waɗannan ƙwayoyin zasu rage HbA1c ɗinka ko matakan sikarin jini zai dogara da dalilai da yawa, gami da:

• matakan jinin ku lokacin da kuka fara magani
• tsarin abincinku da tsarin motsa jiki
• sauran magungunan ciwon suga da kuke sha
• yadda kake bin tsarin kulawa da kai

Kudin

Soliqua 100/33 da Victoza duka magunguna ne masu alamar iri. A halin yanzu babu nau'ikan sifofin da ake samu na ko dai magunguna. Magungunan sunaye suna yawanci suna da tsada fiye da na zamani.

Dangane da ƙididdiga daga GoodRx.com, Victoza gabaɗaya yana tsada fiye da Soliqua 100/33. Gaskiyar kuɗin da za ku biya don ko dai magani zai dogara ne akan sashin ku, shirin inshorar ku, wurin ku, da kuma kantin da kuke amfani da shi.

Soliqua 100/33 vs. Toujeo

Soliqua 100/33 ya ƙunshi kwayoyi biyu:

• insulin glargine, wanda shine insulin mai aiki tsawon lokaci
• lixisenatide, wanda ke cikin rukunin magungunan da ake kira masu kamuwa da agonists masu kama da peptide 1 (GLP-1)

Insulin glargine shine maganin da ke cikin Toujeo. Saboda Soliqua 100/33 da Toujeo suna raba abu mai aiki, suna aiki iri ɗaya a cikin jiki.

Yana amfani da

Soliqua 100/33 an yarda da FDA don inganta matakan sikarin jini a cikin manya da ciwon sukari na 2. An yarda don amfani tare da canjin abinci da motsa jiki.

Toujeo an yarda da FDA don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2, da manya da yara masu ciwon sukari na 1.

Magungunan ƙwayoyi da gudanarwa

Soliqua 100/33 da Toujeo duk sun zo azaman maganin ruwa ne a cikin alƙalamin allurar yarwa. Dukansu magungunan suna yin allurar kai tsaye a ƙarƙashin fata (subcutaneous) sau ɗaya a rana.

Soliqua 100/33 ya zo cikin adadin daya. Kowane alkalami yana dauke da 3 mL na maganin magani, tare da raka'a 300 na insulin glargine da 100 mcg na lixisenatide. Matsakaicin matsakaici a kowace allura ita ce raka'a 60, wanda ke nufin raka'a 60 na insulin glargine da 20 mcg lixisenatide.

Toujeo ya zo da yawa biyu:

• Toujeo SoloStar ya ƙunshi sassan insulin glargine a cikin 1.5 mL na bayani, tare da matsakaicin adadin kashi 80 na allura.
• Toujeo Max SoloStar ya ƙunshi rarar insulin glargine 900 a cikin 3 mL na bayani, tare da matsakaicin kashi na raka'a 160 a kowane allura.

Sakamakon sakamako da kasada

Soliqua 100/33 da Toujeo duk suna raba insulin mai aiki na dogon lokaci, insulin glargine. Sabili da haka, magungunan biyu na iya haifar da sakamako mai kama da juna. Da ke ƙasa akwai misalai na waɗannan tasirin.

Commonarin sakamako masu illa na kowa

Wadannan jerin suna dauke da misalai na cututtukan cututtukan da suka fi dacewa wanda zai iya faruwa tare da Soliqua 100/33, tare da Toujeo, ko kuma tare da magungunan biyu (lokacin da aka ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
  • tashin zuciya
  • gudawa
  • ciwon kai
• Zai iya faruwa tare da Toujeo:
  • riba mai nauyi
  • allurar shafin halayen
  • lipodystrophy (rashin fahimta ko damuwa a yankin allura)
  • ƙaiƙayi
  • kurji
  • kumburi a ƙafafunku, idon sawu, ko ƙafa
• Zai iya faruwa tare da duka Soliqua 100/33 da Toujeo:
  • cututtukan da suka shafi numfashi irin su sanyi ko mura
  • hypoglycemia (ƙarancin sukarin jini)

M sakamako mai tsanani

Waɗannan jerin suna ƙunshe da misalai na larura masu haɗari waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Toujeo, ko tare da magungunan duka biyu (lokacin ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
  • pancreatitis (kumburi na pancreas)
  • lalacewar koda
• Zai iya faruwa tare da Toujeo:
  • uniquean ƙananan sakamako masu illa na musamman
• Zai iya faruwa tare da duka Soliqua 100/33 da Toujeo:
  • mai tsanani rashin lafiyan dauki
  • tsananin hypoglycemia (mai saurin sukari a cikin jini)
  • hypokalemia (ƙananan matakan potassium)

Inganci

Ba a kwatanta Soliqua 100/33 da Toujeo kai tsaye a cikin nazarin asibiti. Koyaya, binciken mutum ya nuna cewa duka Toujeo da Soliqua 100/33 na iya zama masu tasiri wajen rage duka HbA1c da saurin sukarin jini.

• A cikin binciken asibiti, Soliqua 100/33 ya rage haemoglobin A1c (HbA1c) da kashi 1.1 kuma ya yi sauri da saurin sukarin jini da 5.7 mg / dL bayan makonni 30 na magani.
• A wasu karatun na asibiti, Toujeo ya rage HbA1c da kimanin kashi 0.73 zuwa 1.42 da kuma saurin sukarin jini ta hanyar 18 zuwa 61 mg / dL sama da makonni 26 na magani.

Lura: Yana da mahimmanci a tuna cewa yadda ɗayan waɗannan ƙwayoyin zasu rage HbA1c ɗinka ko matakan sikarin jini zai dogara da dalilai da yawa, gami da:

• matakan sukarin jininka lokacin da ka fara magani
• tsarin abincinku da tsarin motsa jiki
• sauran magungunan ciwon suga da kuke sha
• yadda kake bin tsarin kulawa da kai

Kudin

Soliqua 100/33 da Toujeo duka magunguna ne masu alamar iri. A halin yanzu babu nau'ikan sifofin da ake samu na ko dai magunguna. Magungunan sunaye suna yawanci suna da tsada fiye da na zamani.

Dangane da ƙididdiga daga GoodRx.com, Toujeo gabaɗaya yana tsada fiye da Soliqua 100/33. Ainihin farashin da zaku biya don ko dai magani zai dogara ne akan adadin ku, shirin inshorar ku, wurin ku, da kuma kantin da kuke amfani dashi.

Soliqua 100/33 vs. Adlyxin

Soliqua 100/33 ya ƙunshi kwayoyi biyu:

• insulin glargine, wanda shine insulin mai aiki tsawon lokaci
• lixisenatide, wanda ke cikin rukunin magungunan da ake kira masu kamuwa da agonists masu kama da peptide 1 (GLP-1)

Lixisenatide kuma magani ne da ke cikin Adlyxin. Saboda Soliqua 100/33 da Adlyxin suna raba abu mai aiki, suna aiki iri ɗaya a cikin jiki.

Yana amfani da

Soliqua 100/33 an yarda da FDA don amfani tare da canjin abinci da motsa jiki don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2.

Adlyxin an yarda da FDA don amfani tare da abinci da motsa jiki don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2.

Magungunan ƙwayoyi da gudanarwa

Soliqua 100/33 da Adlyxin duk sun zo azaman maganin ruwa a cikin alƙalamin allurar da za a yarwa. Dukansu magungunan suna yin allurar kai tsaye a ƙarƙashin fata (subcutaneous) sau ɗaya a rana.

Alƙalamin Soliqua 100/33 ya zo cikin adadin guda. Kowane alkalami ya ƙunshi 3 mL na maganin magani, tare da raka'a 100 na insulin glargine da 33 mcg na lixisenatide a kowace mL. Matsakaicin matsakaici a kowace allura ita ce raka'a 60, wanda ke nufin raka'a 60 na insulin glargine da 20 mcg lixisenatide.

Alƙalamin Adlyxin ya zo da yawa daban-daban:

• Alƙalamin kore Adlyxin ya ƙunshi 50 mcg / mL a cikin 3 mL na bayani, tare da kashi 10 mcg ta allura.
• Alƙalami na burgundy Adlyxin ya ƙunshi 100 mcg / mL a cikin 3 mL na bayani, tare da kashi na 20 mcg ta allura.

Sakamakon sakamako da kasada

Soliqua 100/33 da Adlyxin duk suna dauke da sinadarin lixisenatide. Sabili da haka, duka magunguna na iya haifar da sakamako mai kama da juna. Da ke ƙasa akwai misalai na waɗannan tasirin.

Commonarin sakamako masu illa na kowa

Waɗannan jerin suna ƙunshe da misalai na cututtukan da suka fi dacewa waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Adlyxin, ko tare da magungunan duka biyu (lokacin da aka ɗauka ɗayansu).

• Zai iya faruwa tare da Soliqua 100/33:
  • cututtukan da suka shafi numfashi irin su sanyi ko mura
• Zai iya faruwa tare da Adlyxin:
  • amai
  • jiri
• Zai iya faruwa tare da duka Soliqua 100/33 da Adlyxin:
  • tashin zuciya
  • gudawa
  • ciwon kai
  • hypoglycemia (ƙarancin sukarin jini)

M sakamako mai tsanani

Waɗannan jerin suna ƙunshe da misalai na larura masu haɗari waɗanda zasu iya faruwa tare da Soliqua 100/33, tare da Adlyxin, ko tare da magungunan duka biyu (lokacin ɗauka daban-daban).

• Zai iya faruwa tare da Soliqua 100/33:
  • hypokalemia (ƙananan matakan potassium)
• Zai iya faruwa tare da Adlyxin:
  • uniquean ƙananan sakamako masu illa na musamman
• Zai iya faruwa tare da duka Soliqua 100/33 da Adlyxin:
  • mai tsanani rashin lafiyan dauki
  • tsananin hypoglycemia (mai saurin sukari a cikin jini)
  • pancreatitis (kumburi na pancreas)
  • lalacewar koda

Inganci

Amfani da ko dai Soliqua 100/33 ko Adlyxin azaman magani guda ɗaya don cutar ciwon sukari na 2 ba a kwatanta shi kai tsaye ba a cikin binciken asibiti.Koyaya, an kwatanta amfani da kowane magani a haɗe tare da metformin (maganin ciwon sukari na baka) kai tsaye.

Raba karatu lokacin amfani dashi shi kaɗai

A cikin nazarin ilimin likita daban, Soliqua 100/33 da Adlyxin duka suna da tasiri kaɗai wajen rage saurin sukarin jini a cikin waɗanda ke da ciwon sukari na 2.

• A cikin binciken asibiti, Soliqua 100/33 ya rage haemoglobin A1c (HbA1c) da kashi 1.1 kuma ya yi sauri da saurin sukarin jini da 5.7 mg / dL bayan makonni 30 na magani.
• A wani binciken asibiti na daban, Adlyxin ya rage HbA1c da kashi 0.57 zuwa kashi 0.71 kuma ya yi sauri ya hauhawan sikari a cikin kashi 4.48 zuwa 24.56 mg / dL sama da makonni 24 na magani.

Kwatancen kai tsaye lokacin amfani da metformin

Wani binciken ya gwada amfani da Soliqua 100/33 tare da metformin kai tsaye game da amfani da Adlyxin tare da metformin a cikin manya masu ciwon sukari na 2. Mutanen da aka yi nazarin a baya an sha su da metformin ita kadai, ko kuma tare da metformin da kuma wani maganin ciwon sikari na baka.

Bayan makonni 30, Soliqua 100/33 tare da metformin ya fi Adlyxin tasiri tare da metformin. Soliqua 100/33 tare da metformin ya rage HbA1c da kashi 1.6 da kuma saurin sukarin jini da 59.1 mg / dL. Adlyxin da metformin, a gefe guda, sun rage HbA1c da kashi 0.9 da kuma saurin sukarin jini da 27.2 mg / dL.

Lura: Yana da mahimmanci a tuna cewa yadda ɗayan waɗannan ƙwayoyin zasu rage HbA1c ɗinka ko matakan sikarin jini zai dogara da dalilai da yawa, gami da:

• matakan sukarin jininka lokacin da ka fara magani
• tsarin abincinku da tsarin motsa jiki
• sauran magungunan ciwon suga da kuke sha
• yadda kake bin tsarin kulawa da kai

Kudin

Soliqua 100/33 da Adlyxin duka magunguna ne masu alamar iri. A halin yanzu babu nau'ikan sifofin da ake samu na ko dai magunguna. Magungunan sunaye suna yawanci suna da tsada fiye da na zamani.

Dangane da ƙididdiga daga GoodRx.com, Adlyxin gabaɗaya yana tsada fiye da Soliqua 100/33. Ainihin farashin da za ku biya don ko dai magani zai dogara ne akan sashin ku, shirin inshorar ku, wurin ku, da kuma kantin da kuke amfani da shi.

A watan Mayu na 2020, Hukumar Abinci da Magunguna (FDA) ta ba da shawarar cewa wasu masu yin metformin da aka ba da izinin cire wasu allunan daga kasuwar Amurka. Wannan saboda an sami matakin da ba za a yarda da shi ba na kwayar cutar sankara (wakili mai haddasa cutar kansa) a cikin wasu karafunan maganin metformin. Idan a halin yanzu kun sha wannan magani, kira likitan ku. Za su ba da shawara ko ya kamata ku ci gaba da shan magungunanku ko kuma idan kuna buƙatar sabon takardar sayan magani.

Soliqua 100/33 amfani

Hukumar Abinci da Magunguna (FDA) ta amince da magungunan ƙwayoyi irin su Soliqua 100/33 don magance wasu sharuɗɗa. Soliqua 100/33 an yarda da FDA don amfani tare da canjin abinci da motsa jiki don inganta matakan sukarin jini a cikin manya masu ciwon sukari na 2.

A cikin binciken asibiti na makonni 30 na mutanen da aka yiwa magani da nau'in insulin basal (kamar su insulin glargine), an gano Soliqua 100/33 yana da tasiri. Ya rage haemoglobin A1c (HbA1c) da kashi 1.1 bisa ɗari kuma yana yin saurin sukarin jini da 5.7 mg / dL.

Nazarin asibiti na makonni 30 ya maida hankali ne kan mutanen da aka yiwa magani tare da metformin shi kaɗai, ko kuma tare da metformin da kuma wani maganin ciwon sukari na baka. Ga mutanen da ke cikin binciken, Soliqua 100/33 da metformin sun rage HbA1c da kashi 1.6 da kuma saurin sukarin jini da 59.1 mg / dL.

Soliqua 100/33 amfani tare da wasu magunguna

Ana iya amfani da Soliqua 100/33 shi kaɗai ko a hade tare da wasu magunguna don inganta matakan sukarin jini a cikin mutane masu ciwon sukari na 2. A cikin maganin ciwon sukari, yana da mahimmanci don amfani da magani fiye da ɗaya don amfani da shi don sarrafa matakan sikarin jini idan magani ɗaya kaɗai bai inganta matakan sukarin jini sosai ba.

Misalan magunguna waɗanda za a iya amfani dasu tare da Soliqua 100/33 sun haɗa da:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• gillypiride (Amaryl)
• gipizide (Glucotrol)
• glyburide (DiaBeta, Glynase)
• metformin (Glucophage, Glumetza, Ruwan kwalliya)
• pioglitazone (Actos)

Soliqua 100/33 da barasa

Guji shan giya da yawa yayin shan Soliqua 100/33. Barasa na iya canza matakan sikirinka na jini kuma ya ƙara haɗarin hypoglycemia (ƙarancin sukari a cikin jini) da pancreatitis (kumburin ciki).

Idan ka sha giya, yi magana da likitanka game da yadda giya ke da lafiya a gare ka.

Soliqua 100/33 ma'amala

Soliqua 100/33 na iya ma'amala da wasu magunguna da yawa. Hakanan yana iya ma'amala tare da wasu abubuwan haɓaka da wasu abinci.

Hanyoyi daban-daban na iya haifar da sakamako daban-daban. Misali, wasu na iya tsoma baki game da yadda kwayoyi ke aiki da kyau, yayin da wasu na iya haifar da ƙarin illa.

Soliqua 100/33 da sauran magunguna

Da ke ƙasa akwai jerin magungunan da za su iya hulɗa tare da Soliqua 100/33. Wannan jeren ba ya ƙunsar duk magungunan da zasu iya hulɗa da Soliqua 100/33.

Kafin shan Soliqua 100/33, tabbas ka gaya wa likitanka da likitan magunguna game da duk takardar sayen magani, kan-kan-kanta, da sauran magungunan da kake sha. Har ila yau, gaya musu game da kowane bitamin, ganye, da abubuwan da kuke amfani da su. Raba wannan bayanin na iya taimaka maka ka guji yiwuwar mu'amala.

Idan kuna da tambayoyi game da ma'amalar miyagun ƙwayoyi waɗanda zasu iya shafar ku, tambayi likitan ku ko likitan magunguna.

Sauran magungunan suga

Shan Soliqua 100/33 tare da wasu magungunan ciwon sikari na iya haifar da matsanancin matakin sikarin jini da kuma kara kasadar kamuwa da cutar hypoglycemia (karancin sukarin jini). Idan ka ɗauki ɗayan waɗannan magunguna, ƙila kana buƙatar bincika matakan sukarin jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan magunguna masu ciwon suga sun haɗa da:

• canagliflozin (Invokana)
• dapagliflozin (Farxiga)
• empagliflozin (Jardiance)
• glyburide (DiaBeta, Glynase, Micronase)
• gillypiride (Amaryl)
• gipizide (Glucotrol)
• insulin-lokacin cin abinci (Humalog, Novolog)
• metformin (Glucophage)
• nateglinide (Starlix)
• maimaitawa (Prandin)

Bugu da kari, amfani da Soliqua 100/33 tare da magungunan sikari wanda ake kira thiazolidinediones (TZDs) na iya haifar da riƙe ruwa. Hakanan yana iya ƙara haɗarin rashin nasarar zuciyarka ko ɓarke ​​alamomin gazawar zuciya (duba gargaɗi a ƙasa). Misalan waɗannan kwayoyi sun haɗa da:

• pioglitazone (Actos)
• rosiglitazone (Avandia)

Idan kana shan TZD, yi magana da likitanka kafin fara Soliqua 100/33. Idan likitanka ya yarda da amfaninka na TZD yayin amfani da Soliqua 100/33, tabbatar da kulawa don alamun rashin cin nasara zuciya. Idan ka ci gaba da ciwon zuciya, likitanka na iya rage adadin TZD ɗinka ko ka daina shan shi.

Kwayar cututtukan zuciya na iya haɗawa da:

• matsalar numfashi
• kumburi a kafafu, idon kafa, da ƙafa
• sauri ko bugun zuciya mara tsari
• ciwon kirji

Magungunan hawan jini

Shan Soliqua 100/33 tare da wasu magungunan hawan jini na iya haifar da matsanancin matakin sikarin jini da kuma kara kasadar kamuwa da cutar hypoglycemia (karancin sukarin jini). Idan ka ɗauki ɗayan waɗannan magunguna, ƙila kana buƙatar bincika matakan sukarin jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan magungunan hawan jini waɗanda zasu iya haɓaka haɗarin hypoglycemia yayin ɗauka tare da Soliqua 100/33 sun haɗa da:

• angiotensin-converting enzyme (ACE) masu hanawa, kamar su:
• benazepril (Lotensin)
• captopril
• enalapril (Vasotec)
• lilkancin (Zestril)
• angiotensin II masu karɓa masu karɓa (ARBs), kamar:
• valsartan (Diovan)
• candesartan (Atacand)
• irbesartan (Avapro)
• losartan (Cozaar)
• olmesartan (Benicar)

Sauran magunguna masu hawan jini na iya rufe alamun alamun ƙananan ƙarancin sukarin jini. Hakanan waɗannan kwayoyi na iya ƙaruwa ko rage yadda tasirin Soliqua 100/33 yake game da rage matakan sukarin jini. Idan ka sha wadannan magungunan tare da Soliqua 100/33, zaka iya bukatar duba matakan suga na jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan magungunan hawan jini waɗanda zasu iya ɓoye alamun ƙananan hawan jini ko tasiri yadda Soliqua 100/33 ke aiki sun haɗa da:

• clonidine (Catapres)
• metoprolol (Lopressor, Toprol-XL)
• atenolol (Tenormin)

Sauran kwayoyi da zasu iya ɓoye alamun hypoglycemia

Wasu magunguna na iya rufe alamomi da alamomin ƙananan matakan sikarin jini. Idan ka sha wadannan magungunan, zaka iya bukatar duba matakan suga na jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan waɗannan magunguna sun haɗa da:

• albuterol (ProAir, Proventil, Ventolin)
• guanethidine
• wurin ajiye ruwa

Sauran magunguna wadanda zasu iya rage matakan suga cikin jini

Shan Soliqua 100/33 tare da wasu magunguna na iya haifar da matsanancin matakin sikarin cikin jini da kuma kara kasadar kamuwa da cutar hypoglycemia (karancin sukarin jini). Idan ka ɗauki ɗayan waɗannan magunguna, ƙila kana buƙatar bincika matakan sukarin jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan waɗannan magunguna sun haɗa da:

• rashin tsari (Norpace)
• wasu magungunan cholesterol, kamar fenofibrate (Tricor, Triglide) da gemfibrozil (Lopid)
• wasu magungunan kashe jini, kamar su fluoxetine (Prozac, Sarafem) da selegiline (Emsam, Zelapar)
• octreotide (Sandostatin)
• sulfamethoxazole-trimethophop (Bactrim, Satumba)

Sauran magunguna wadanda suke kara yawan suga a cikin jini

Wasu magunguna na iya kara yawan sukarin jini a jikin ku. Idan ka sha wadannan magunguna, zaka iya duba matakan suga na jininka sau da yawa don hana hawan jini (hawan jini). Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan waɗannan magunguna sun haɗa da:

• albuterol (ProAir, Proventil, Ventolin)
• wasu kwayoyin cutar, kamar atazanavir (Reyataz) da lopinavir / ritonavir (Kaletra)
• wasu magunguna, kamar budesonide (Entocort EC, Pulmicort, Uceris), prednisone, da fluticasone (Flonase, Flovent)
• wasu masu maganin diure, kamar su chlorothiazide (Diuril) da hydrochlorothiazide (Microzide)
• wasu magungunan kashe kwakwalwa, kamar su clozapine (Clozaril, Fazaclo) da olanzapine (Zyprexa)
• wasu kwayoyin hormones, kamar danazol (Danazol), levothyroxine (Levoxyl, Synthroid) da somatropin (Genotropin)
• glucagon (GlucaGen)
• niacin (Niaspan, Slo-Niacin, wasu)
• magungunan hana daukar ciki (kwayoyin hana haihuwa)

Magungunan da ke haɓaka ko rage tasirin Soliqua 100/33

Wasu magunguna na iya shafar yadda Soliqua 100/33 ke aiki a jikinku. Idan ka sha wadannan magungunan, zaka iya bukatar duba matakan suga na jininka sau da yawa. Hakanan, likitanku na iya buƙatar canza sashin ku na Soliqua 100/33.

Misalan waɗannan magunguna sun haɗa da:

• albuterol (ProAir, Proventil, Ventolin)
• lithium

Soliqua 100/33 da ganye da kari

Shan Soliqua 100/33 tare da wasu ganyayyaki ko kari na iya kara barazanar hypoglycemia (ƙananan matakan sikarin jini). Misalan waɗannan sun haɗa da:

• alpha-lipoic acid
• banaba
• guna mai daci
• chromium
• gidan motsa jiki
• murtsataccen pear cactus
• farin Mulberry

Yadda Soliqua 100/33 yake aiki

Soliqua 100/33 na taimakawa inganta matakan sikarin jini a cikin mutane masu ciwon sukari na 2.

Ta yaya insulin ke shafar sukarin jini

A ka’ida, idan ka ci abinci, jikinka yana fitar da wani sinadarin da ake kira insulin. Glucose (sukari) daga abinci yana tafiya zuwa hanyoyin jini, kuma insulin yana taimakawa safarar shi zuwa cikin ƙwayoyin jikinku. Kwayoyin suna juya glucose zuwa makamashi.

Mutanen da ke da ciwon sukari na 2 yawanci suna da ƙarfin insulin. Wannan yana nufin jikinsu baya amsa insulin yadda ya kamata. Bayan lokaci, mutanen da ke da ciwon sukari na 2 na iya daina samar da isasshen insulin.

Lokacin da jikinku ba ya amsa insulin yadda ya kamata, ko kuma idan ba ta samar da isasshen insulin ba, wannan na haifar da matsala. Kwayoyin jikinku bazai sami glucose da suke buƙata suyi aiki daidai ba.

Hakanan, kuna iya samun glucose mai yawa a cikin jinin ku. Wannan shi ake kira hyperglycemia (hawan jini mai nauyi). Samun yawan glucose a cikin jini na iya lalata jikin ku da gabobin ku, gami da idanun ku, zuciyar ku, jijiyoyin ku, da koda.

Abin da Soliqua 100/33 yake yi

Soliqua 100/33 ya ƙunshi magunguna biyu. Waɗannan sune glargine na insulin, wanda shine insulin mai aiki, da lixisenatide, wanda shine mai karɓar agonist mai kama da peptide 1 (GLP-1).

Insulin glargine yana aiki ta wata hanya: yana saukar da matakan sikarin jininka ta hanyar motsa glucose daga jinin ka zuwa kwayoyin jikin ka.

Lixisenatide yana aiki a hanyoyi uku. Na farko, yana kara adadin insulin da jikinku yake yi. Wannan ƙarin insulin yana taimakawa motsa ƙarin glucose daga jinin ku zuwa cikin ƙwayoyinku. Na biyu, yana sa cikinka ya zama ba komai a hankali bayan cin abinci, yana sa ka ji daɗi sosai. Na uku kuma, yana gayawa hantar ka cewa ta saki mafi karancin glucose cikin jinin ka.

Yaya tsawon lokacin aiki?

Soliqua 100/33 ya fara aiki daidai bayan ka yi masa allurar. Koyaya, yana kaiwa tasirinsa mafi girma kusan awa 2.5 zuwa 3 bayan kowane allura.

Soliqua 100/33 da ciki

Bayanan karatu sun iyakance don amfani da Soliqua 100/33 yayin daukar ciki a cikin mutane. Koyaya, nazarin dabba ya nuna cewa akwai yuwuwar lalacewar haihuwa tare da amfani da lixisenatide yayin daukar ciki. Lixisenatide na daya daga cikin magungunan da ake samu a Soliqua 100/33. Sabili da haka, ya kamata a yi amfani da Soliqua 100/33 ne kawai a lokacin ɗaukar ciki idan fa'idar da take da ita ta fi ƙarfin haɗarin.

Idan kun kasance masu ciki ko shirin yin ciki, yi magana da likitanku game da haɗari da fa'idodi na amfani da Soliqua 100/33 yayin ɗaukar ciki.

Soliqua 100/33 da nono

Ba a sani ba idan Soliqua 100/33 ya shiga cikin nono. Kafin shayarwa, ya kamata ka tattauna da likitanka haɗari da fa'idodin shan wannan magani yayin shayarwa.

Tambayoyi gama gari game da Soliqua 100/33

Anan akwai amsoshi ga wasu tambayoyin da akai akai akai game da Soliqua 100/33.

Shin Soliqua 100/33 yana haifar da karin nauyi?

A cikin gwaji na asibiti, ba a sami Soliqua 100/33 da zai haifar da kiba ba. A zahiri, a cikin binciken asibiti guda ɗaya, mutanen da suka ɗauki Soliqua 100/33 tsawon makonni 30 sun rasa kimanin fam 1.5.

Yana da ban sha'awa a lura cewa ɗayan magungunan da ke cikin Soliqua 100/33 suna da alama suna da sakamako daban-daban akan nauyi. Daya daga cikin magungunan shine insulin glargine, wanda shine insulin mai dadewa. Yawanci, ana danganta magungunan da ke ƙunshe da insulin tare da ƙimar nauyi.

Koyaya, wani magani a cikin Soliqua 100/33 ana kiransa lixisenatide, wanda shine mai kama da pecide 1 (GLP-1) mai karɓar agonist. Magunguna a cikin rukunin magani na GLP-1 sun nuna asarar nauyi azaman sakamako mai illa a cikin karatun asibiti da yawa.

Idan kun damu game da tasirin da Soliqua 100/33 zai iya yi a kan nauyinku, yi magana da likitanku.

Shin Soliqua 100/33 insulin ne?

Ee, Soliqua 100/33 yana dauke da insulin. Soliqua 100/33 an hada shi da magunguna biyu, daya daga cikinsu shine insulin glargine, insulin mai dadewa.

Magani na biyu shine lixisenatide, wanda shine mai kama da peptide 1 (GLP-1) agonist agonist.

Shin Soliqua 100/33 yana da dogon lokaci?

Ee. Soliqua 100/33 ya ƙunshi ƙwayoyi biyu masu aiki. Daya daga cikin wadannan shine insulin glargine, wanda shine insulin mai dadewa.

Shin ana iya amfani da Soliqua 100/33 don magance ciwon sukari na 1?

A'a, bai kamata a yi amfani da Soliqua 100/33 don magance ciwon suga irin na 1 ba. Ba a yi nazarin Soliqua 100/33 ba kuma ba ta yarda da Hukumar Abinci da Magunguna don magance wannan yanayin ba. An yarda ne kawai don magance ciwon sukari na 2.

Gargadin Soliqua 100/33

Kafin shan Soliqua 100/33, yi magana da likitanka game da tarihin lafiyar ku. Soliqua 100/33 bazai dace da ku ba idan kuna da wasu halaye na likita. Wadannan sun hada da:

• Ciwon koda. Idan kana da cutar koda, shan Soliqua 100/33 na iya tsananta maka. Idan yanayinka ya ta'azzara, mai yiwuwa ka daina shan Soliqua 100/33. Kada ku sha wannan magani idan kuna da cutar koda mai tsanani.
• Sannu a hankali wofi. Lixisenatide, ɗayan magunguna a cikin Soliqua 100/33, yana jinkirta aikin tsokar cikinka. Idan kana da gastroparesis, wanda ke nufin jikinka yana narkar da abinci sannu a hankali, shan Soliqua 100/33 na iya lalata yanayinka. Mutanen da ke da cututtukan ciki da yawa ba za su sha wannan magani ba.
• Pancreas ko matsalolin gallbladder, ko matsalar amfani da giya. Soliqua 100/33 na iya ƙara haɗarin cutar pancreatitis. Kuna iya kasancewa cikin haɗarin cutar pancreatitis idan kuna da tarihin cutar sankara, duwatsun gallbladder, ko kuma maye. Idan kana da tarihin waɗannan matsalolin, yi magana da likitanka game da ko Soliqua 100/33 ya dace da kai.

Soliqua 100/33 yawan abin da ya kamata

Shan yawancin wannan magani na iya kara yawan haɗarinku na mummunan sakamako.

Symptomsara yawan ƙwayoyi

Kwayar cututtukan ƙwayar ƙwayar cuta na iya haɗawa da:

• mummunan hypoglycemia (mai tsananin ƙarancin sukari a cikin jini), wanda ke haifar da rauni, damuwa, da rikicewa
• hypokalemia (ƙananan matakan potassium), wanda zai iya haifar da rauni, maƙarƙashiya, da jijiyoyin tsoka
• matsalolin ciki, wanda kan iya haifar gudawa, jiri, da amai

Abin da za a yi idan ya wuce gona da iri

Idan kuna tsammanin kun sha da yawa daga wannan magani, kira likitanku ko ku nemi jagora daga Americanungiyar ofungiyar Kula da Guba ta Amurka a 800-222-1222 ko ta hanyar kayan aikin su na kan layi. Amma idan alamun ka masu tsanani ne, kira 911 ko ka je dakin gaggawa mafi kusa kai tsaye.

Soliqua 100/33 karewa da ajiya

Lokacin da aka fitar da Soliqua 100/33 daga kantin magani, likitan zai ƙara ranar karewa zuwa lakabin akan akwatin. Wannan kwanan wata galibi shekara ɗaya ce daga ranar da aka ba da magani.

Dalilin waɗannan kwanakin karewar shine don tabbatar da ingancin magani a wannan lokacin. Matsayi na Hukumar Abinci da Magunguna ta yanzu (FDA) shine gujewa amfani da magungunan da suka ƙare.

Yaya tsawon magani ya kasance mai kyau na iya dogara da dalilai da yawa, gami da yadda da kuma inda ake adana maganin. Adana alƙaluman Soliqua 100/33 a cikin firinji, a zazzabi tsakanin 36 ° F da 46 ° F (2 ° C da 8 ° C). Kada ka daskare alkalaminka.

Bayan amfani na farko na kowane alkalami, zaka iya adana shi a zazzabin ɗaki (77 ° F / 25 ° C), amma ka tabbata ka kiyaye shi daga haske. Yi watsi da kowane alkalami bayan kwanaki 28 daga amfanin farko.

Idan kana da maganin da ba a amfani da shi wanda ya wuce ranar karewa, yi magana da likitan ka game da ko har yanzu zaka iya amfani da shi.

Bayani na ƙwararru don Soliqua 100/33

Ana ba da bayanin nan na gaba don likitoci da sauran ƙwararrun likitocin kiwon lafiya.

Manuniya

Soliqua 100/33 an yarda da FDA don amfani tare da abinci da motsa jiki don inganta ikon glycemic a cikin manya masu fama da ciwon sukari na 2.

Hanyar aiwatarwa

Soliqua 100/33 hade ne na insulin glargine (analog din basal analog) da lixisenatide (mai kama da peptide 1 [GLP-1] agonist mai kama da glucagon).

Insulin glargine yana rage glucose na jini ta hanyar kara karfin glucose na gefe da rage samar da glucose daga hanta. Lixisenatide yana rage glucose na jini ta hanyar kara kwayar insulin, rage yawan kwayar glucagon, da kuma jinkirin barin ciki.

Pharmacokinetics da metabolism

Yanayin insulin glargine-to-lixisenatide ba shi da tasiri a kan magungunan magani na kowane ɓangaren.

Insulin glargine bashi da kololuwa kuma ana hada shi a wani sashi a tashar carboxyl na sarkar B a cikin rumbun karkashin ruwa.

Lokaci zuwa adadi mai yawa don lixisenatide shine awanni 2.5 zuwa 3. Lixisenatide yana da nauyin haɗin kashi 55 cikin ɗari kuma ana cire shi ta hanyar fitsari da lalacewar proteolytic. Rabin rabin rayuwa kusan awa 3 ne.

Contraindications

Soliqua 100/33 an hana shi cikin marasa lafiya:

• yayin lokuttan hypoglycemic
• tare da tarihin mummunan laulayi ga insulin glargine ko lixisenatide

Ma'aji

Alƙaluman Soliqua 100/33 ya kamata a adana su a cikin firiji, a zazzabi tsakanin 36 ° F da 46 ° F (2 ° C da 8 ° C), amma ba a daskarewa ba. Bayan amfani na farko, ana iya adana alkalama a zazzabi na ɗaki 77 ° F (25 ° C). Yakamata a kiyaye su daga haske. Yi watsi da alkalami bayan kwanaki 28 daga amfani na farko.

Bayanin doka: MedicalNewsToday ta yi iya ƙoƙari don tabbatar da cewa duk bayanan gaskiya ne, cikakke, kuma na zamani. Koyaya, wannan labarin bai kamata ayi amfani dashi azaman madadin ilimi da ƙwarewar ƙwararren likita mai lasisi ba. Ya kamata koyaushe ku tuntuɓi likitanku ko wasu masu sana'a na kiwon lafiya kafin shan kowane magani. Bayanin magani da ke cikin wannan batun na iya canzawa kuma ba ana nufin ya rufe duk amfanin da zai yiwu ba, kwatance, kiyayewa, gargaɗi, hulɗar miyagun ƙwayoyi, halayen rashin lafiyan, ko cutarwa. Rashin gargadin ko wasu bayanai don maganin da aka bayar baya nuna cewa magani ko haɗin magungunan yana da aminci, tasiri, ko dacewa ga duk marasa lafiya ko duk takamaiman amfani.