Yawancin endoprine neoplasia (MAZA) I

Yawancin nau'o'in endoprine neoplasia (MEN) nau'ikan I cuta ce wacce daya ko fiye daga cikin glandon endocrine suke cika aiki ko kuma suka zama ƙari. Yana wucewa ta wurin dangi.

Endocrine gland mafi yawan wadanda suka hada sun hada da:

• Pancreas
• Parathyroid
• Yanayin aiki

MUTANE na ya faru ne sakamakon lahani a cikin kwayar halitta wacce ke dauke da lambar furotin da ake kira menin. Yanayin yana haifar da ciwace-ciwacen ƙwayoyin cuta daban-daban su bayyana a cikin mutum guda, amma ba lallai bane a lokaci guda.

Rashin lafiyar na iya faruwa a kowane zamani, kuma yana shafar maza da mata daidai wa daida. Tarihin iyali na wannan rikicewar yana haifar da haɗarinku.

Kwayar cutar ta bambanta daga mutum zuwa mutum, kuma ya dogara da wace glandar da ke ciki. Suna iya haɗawa da:

• Ciwon ciki
• Tashin hankali
• Baƙi, kujerun tarry
• Mai kumburi bayan abinci
• Ingonawa, ciwo, ko rashin jin daɗin yunwa a cikin babba na sama ko ƙananan kirji wanda aka cire daga antacids, madara, ko abinci
• Rage sha'awar sha'awa
• Gajiya
• Ciwon kai
• Rashin lokacin haila (a cikin mata)
• Rashin ci
• Rashin jiki ko gashin fuska (a cikin maza)
• Canjin tunani ko rikicewa
• Ciwon tsoka
• Tashin zuciya da amai
• Hankali ga sanyi
• Rashin nauyi mara nauyi
• Matsalar hangen nesa
• Rashin ƙarfi

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambayoyi game da tarihin lafiyar ku da alamomin ku. Za a iya yin gwaje-gwaje masu zuwa:

• Matakan cortisol na jini
• CT scan na ciki
• CT scan na kai
• Azumin suga
• Gwajin kwayoyin halitta
• Gwajin insulin
• MRI na ciki
• MRI na kai
• Maganin adrenocorticotropic hormone
• Maganin alli
• Maganin kwayar cuta mai motsa jiki
• Maganin gastrin
• Maganin glucagon
• Magungunan maganin luteinizing
• Maganin parathyroid hormone
• Magani prolactin
• Magungunan maganin karoid mai motsawa
• Duban dan tayi

Yin aikin tiyata don cire glandon mara lafiya galibi shine zaɓin zaɓi. Za'a iya amfani da maganin da ake kira bromocriptine maimakon yin aikin tiyata don ciwace ciwan ciki wanda ke sakin prolactin na hormone.

Za a iya cire glandon parathyroid, wanda ke kula da samar da alli. Koyaya, yana da wahala ga jiki ya daidaita matakan alli ba tare da waɗannan gland ba, saboda haka ba a fara cire ƙarancin parathyroid da farko a mafi yawan lokuta.

Ana samun magani don rage yawan ruwan ciki na ciki wanda wasu ciwace-ciwace (gastrinomas) ke haifarwa, da rage haɗarin olsa.

Ana ba da maganin maye gurbin lokacin da aka cire duka gland ko kuma ba sa samar da isasshen homon.

Cutar ciwan jiki da cututtukan parathyroid yawanci ba su da cutar (mara kyau), amma wasu ciwukan pancreatic na iya zama masu cutar kansa (mugu) kuma su bazu cikin hanta. Wadannan na iya rage tsammanin rai.

Alamomin cututtukan ulcer, ƙarancin sukari a cikin jini, yawan ƙwayar cuta mai yawa a cikin jini, da kuma raunin rashin lafiyar jiki yakan amsa da kyau ga maganin da ya dace.

Ciwan kumburin na iya ci gaba da dawowa. Kwayar cututtuka da rikitarwa sun dogara da wanne gland ke ciki. Binciken yau da kullun da mai ba da sabis ke da mahimmanci.

Kira mai ba ku sabis idan kun lura da alamomin MAZA ko kuma kuna da tarihin iyali na wannan yanayin.

Gwajin dangi na kusa da mutanen da wannan cuta ta ba da shawarar.

Ciwon Wermer; MAZA NI

• Endocrine gland

Yanar gizo Yanar Gizon Cutar Kanjamau ta Kasa. Ka'idojin aikin asibiti a cikin ilimin ilimin halittar jiki (NCCN guideines): ciwan neuroendocrine. Sigar 1.2019. www.nccn.org/professionals/physician_gls/pdf/neuroendocrine.pdf. An sabunta Maris 5, 2019. An shiga Maris 8, 2020.

Newey PJ, Thakker RV. Yawancin endoprine neoplasia. A cikin: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Littafin Williams na Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: babi na 42.

Nieman LK, Spiegel AM. Cutar polyglandular. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 218.

Thakker RV. Yawancin nau'in neoplasia na endocrine 1. A cikin: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Manya da Yara. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 148.