Ciwon Cushing saboda ƙari

Ciwon Cushing saboda ciwon sankara wani nau'i ne na ciwon Cushing. Yana faruwa lokacin da ƙari na gland adrenal ya sake adadin mai yawa na hormone cortisol.

Cutar ciwo ta Cushing cuta ce da ke faruwa yayin da jikinka ya sami matakin da ya fi na al'ada na hormone cortisol. Wannan hormone ana yin sa ne a cikin gland adrenal. Cortisol da yawa na iya zama saboda matsaloli daban-daban. Suchaya daga cikin irin wannan matsalar shine ƙari a ɗayan gland adrenal. Ciwan kumburin ciki yana sakin cortisol.

Orswayar cutar adrenal ba safai ba. Suna iya zama marasa ciwo (marasa lafiya) ko masu cutar kansa (mugu).

Tumananan cututtukan da ba za su iya haifar da ciwo na Cushing ba sun haɗa da:

• Adrenal adenomas, ciwan tumor wanda ba kasafai yake yin cortisol mai yawa ba
• Macronodular hyperplasia, wanda ke haifar da adrenal gland ya kara girma da yin cortisol mai yawa

Tumwayoyin cututtukan da ke haifar da ciwo na Cushing sun haɗa da adrenal carcinoma. Wannan ƙananan ƙwayar cuta ne, amma yawanci yana haifar da cortisol mai yawa.

Yawancin mutane da ke fama da cutar Cushing suna da:

• Zagaye, ja, cike da fuska (fuskar wata)
• Saurin girma cikin yara
• Rage nauyi tare da tara kitse a jikin akwati, amma asarar mai daga hannu, kafafu, da gindi (tsakiyar kiba)

Canje-canje na fata waɗanda ake yawan gani:

• Cututtukan fata
• Alamar madaidaiciya mai tsayi (inci 1/2 ko inci 1 ko mafi faɗi), ana kiranta striae, akan fatar ciki, cinyoyi, hannuwan hannu na sama, da ƙirjin
• Fata mai laushi tare da raunin rauni

Muscle da kashi canje-canje sun hada da:

• Ciwon baya, wanda ke faruwa tare da ayyukan yau da kullun
• Ciwon ƙashi ko taushi
• Tarin kitse tsakanin kafadu da sama da abin wuya
• Rib da kasusuwa na kashin baya wanda aka samu sakamakon siririn kasusuwa
• Musclesarfin tsokoki, musamman na kwatangwalo da kafaɗu

Canje-canje na jiki (na tsari) sun haɗa da:

• Rubuta ciwon sukari na 2
• Hawan jini
• Choara yawan cholesterol da triglycerides

Mata suna da:

• Girman gashi mai yawa a fuska, wuya, kirji, ciki, da kuma cinya (ya fi na kowa a wasu nau'ikan ciwo na Cushing)
• Lokutan da suka zama marasa tsari ko tsayawa

Maza na iya samun:

• Rage ko babu sha'awar yin jima'i (low libido)
• Matsalar tashin hankali

Sauran cututtukan da za su iya faruwa sun haɗa da:

• Canje-canjen tunani, kamar ɓacin rai, damuwa, ko canje-canje a ɗabi'a
• Gajiya
• Ciwon kai
• Thirstarin ƙishirwa da fitsari

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamunku.

Gwaji don tabbatar da cutar Cushing:

• Samfurin fitsari na awa 24 don auna matakan cortisol da na halitta
• Gwajin jini don bincika ACTH, cortisol, da matakan potassium
• Dexamethasone danniya gwajin
• Matakan cortisol na jini
• Matakin DHEA na jini
• Matsayin cortisol

Gwaje-gwaje don sanin musababi ko rikitarwa sun haɗa da:

• CT na ciki
• ACTH
• Yawan ma'adinai na ƙashi
• Cholesterol
• Azumin glucose

Ana yin aikin tiyata don cire ƙwayar ƙwayar cuta. Sau da yawa, ana cire dukkan glanden adrenal.

Yawancin lokaci ana buƙatar maganin maye gurbin Glucocorticoid har sai ɗayan glandon ya murmure daga tiyata. Kuna iya buƙatar wannan magani na tsawon watanni 3 zuwa 12.

Idan tiyata ba zai yiwu ba, kamar a cikin yanayin kansar adrenal wanda ya yadu (metastasis), ana iya amfani da magunguna don dakatar da sakin cortisol.

Mutanen da ke da ƙari wanda ke yin tiyata suna da kyakkyawan fata. Don ciwon daji na adrenal, tiyata wani lokaci ba zai yiwu ba. Lokacin da ake aikin tiyata, ba koyaushe yake magance kansar ba.

Orswayoyin cututtukan daji na iya yadawa zuwa hanta ko huhu.

Kira mai ba ku sabis idan kun ci gaba da alamun bayyanar cutar ta Cushing.

Yin maganin da ya dace da ciwace-ciwacen daji na iya rage haɗarin rikitarwa a cikin wasu mutane da ke fama da ciwon kumburin Cushing.

Ciwan ciki - Ciwan Cushing

• Endocrine gland
• Adrenal metastases - CT dubawa
• Adrenal Tumor - CT

Asban A, Patel AJ, Reddy S, Wang T, Balentine CJ, Chen H. Ciwon daji na tsarin endocrine. A cikin: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff na Clinical Oncology. Na 6 ed. Philadelphia, PA: Elsevier; 2020: babi na 68.

Nieman LK, Biller BM, Findling JW, et al. Jiyya na ciwo na Cushing: jagorar aikin likita na Endocrine Society. J Clin Endocrinol Metab. 2015; 100 (8): 2807-2831. PMID: 26222757 www.ncbi.nlm.nih.gov/pubmed/26222757.

Stewart PM, Newell-Price JDC. Tsarin adrenal. A cikin: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Littafin Williams na Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: babi na 15.