Myelofibrosis

Cutar Myelofibrosis cuta ce ta ɓarna wanda aka maye gurbin da bargon da kayan tabon fibrous.

Marasusuwan ƙashi shine mai taushi, nama mai ƙashi a cikin kashin ka. Kwayoyin kara sune kwayoyin halitta wadanda basu balaga ba a cikin kasusuwan kasusuwa wadanda suke bunkasa cikin dukkanin kwayoyin jininka. An sanya jininka daga:

• Kwayoyin jini ja (wanda ke ɗauke da iskar oxygen zuwa kayan jikinku)
• Farin jini (wanda ke yaki da kamuwa da cuta)
• Platelets (wanda ke taimakawa jini ya hau)

Lokacin da kashin baya ya yi rauni, ba zai iya yin wadatattun ƙwayoyin jini ba. Anaemia, matsalolin zub da jini, da haɗarin kamuwa da cututtuka na iya faruwa.

A sakamakon haka, hanta da baƙin ciki suna ƙoƙarin yin wasu daga waɗannan ƙwayoyin jini. Wannan yana sa waɗannan gabobin su kumbura.

Dalilin cutar myelofibrosis galibi ba a sani ba. Babu sanannun abubuwan haɗari. Idan ya faru, yakan zama sannu a hankali cikin mutane sama da shekaru 50. Mata da maza suna daidai da abin. Akwai ƙarin faruwar wannan yanayin a cikin yahudawan Ashkenazi.

Jini da cututtukan kasusuwa, kamar su myelodysplastic syndrome, cutar sankarar bargo, da lymphoma, na iya haifar da raunin ƙashi. Wannan ana kiransa myelofibrosis na biyu.

Kwayar cutar na iya haɗawa da ɗayan masu zuwa:

• Ciki cikakke, zafi, ko jin cikakken abinci kafin a gama cin abinci (saboda faɗaɗa saifa)
• Ciwon ƙashi
• Sauke jini mai sauƙi, rauni
• Gajiya
• Asedarin yiwuwar kamuwa da cuta
• Fata mai haske
• Breatharancin numfashi tare da motsa jiki
• Rage nauyi
• Zufar dare
• Gradeananan zazzabi
• Liverara hanta
• Dry tari
• Fata mai kaushi

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamun.

Gwajin da za a iya yi sun hada da:

• Kammala lissafin jini (CBC) tare da shafa jini don bincika nau'ikan ƙwayoyin jini
• Auna lalacewar nama (matakin LDH enzyme)
• Gwajin kwayoyin halitta
• Gwajin kasusuwa don bincikar yanayin da kuma bincika kansar ƙashi

Kashin kashin jini ko dasawar kwayar halitta na iya inganta alamomin, kuma zai iya warkar da cutar. Wannan magani yawanci ana la'akari dashi ga matasa.

Sauran magani na iya haɗawa da:

• Karin jini da magunguna don gyara karancin jini
• Radiation da chemotherapy
• Magunguna masu niyya
• Cire ƙwayar mara (splenectomy) idan kumburi yana haifar da alamomi, ko don taimakawa cutar rashin jini

Yayinda cutar ta ta'azzara, sannu a hankali kashin kashi ya daina aiki. Countididdigar ƙarancin platelet yana haifar da sauƙin zubar jini. Saurin kumburi na iya zama mafi muni tare da karancin jini.

Rayuwar mutane tare da ƙwayar myelofibrosis na farko kusan shekaru 5 ne. Amma wasu mutane suna rayuwa tsawon shekaru.

Matsaloli na iya haɗawa da:

• Developmentaddamar da cutar sankarar myelogenous mai saurin gaske
• Cututtuka
• Zuban jini
• Jinin jini
• Rashin hanta

Yi alƙawari tare da mai ba da sabis idan kuna da alamun wannan matsalar. Bincika likita nan da nan don zub da jini ba tare da izini ba, rashin numfashi, ko jaundice (launin rawaya da fararen idanu) wanda ke ƙara muni.

Idiopathic myelofibrosis; Myeloid metaplasia; Agnogenic myeloid metaplasia; Myelofibrosis na farko; Secondary myelofibrosis; Kashin kashin jini - myelofibrosis

Gotlib J. Polycythemia vera, thrombocythemia mai mahimmanci, da myelofibrosis na farko. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 157.

Long NM, Kavanagh EC. Myelofibrosis. A cikin: Paparoma TL, Bloem HL, Beltran J, Morrison WB, Wilson DJ, eds. Hoto na Musculoskeletal. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2015: babi na 76.

Mascarenhas J, Najfeld V, Kremyanskaya M, Keyzner A, Salama ME, Hoffman R. Myelofibrosis na Farko. A cikin: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Ka'idoji da Aiki. 7th ed. Philadelphia, PA: Elsevier; 2018: babi na 70.