Antiphospholipid ciwo - APS

Antiphospholipid syndrome (APS) cuta ce ta cikin jiki wanda ke ɗauke da yawan jini (thromboses).Lokacin da kake da wannan yanayin, garkuwar jikinku tana yin sunadaran da ba na al'ada ba waɗanda ke kai hari kan ƙwayoyin jini da rufin jijiyoyin jini. Kasancewar wadannan kwayoyin cuta na iya haifar da matsaloli game da gudan jini kuma zai iya haifar da daskarewa a cikin jijiyoyin jini cikin jiki.

Ba a san ainihin dalilin APS ba. Dukansu wasu canje-canje na kwayar halitta da sauran abubuwan (kamar kamuwa da cuta) na iya haifar da matsalar ci gaba.

An samo shi sau da yawa a cikin mutanen da ke da wasu cututtukan cututtukan zuciya, irin su lupus erythematosus na tsari (SLE). Yanayin ya fi dacewa ga mata fiye da na maza, Galibi ana samun hakan ne ga mata waɗanda suke da tarihin ɓatan ciki sau da yawa.

Wasu mutane suna ɗauke da ƙwayoyin cuta waɗanda aka ambata a sama, amma ba su da APS. Wasu abubuwanda ke haifar dasu na iya haifar da wadannan mutane samun daskarewar jini, gami da:

• Shan taba
• Kwancen gado na dogon lokaci
• Ciki
• Maganin Hormone ko magungunan hana haihuwa
• Ciwon daji
• Ciwon koda

Kila ba ku da alamun cuta, duk da cewa kuna da ƙwayoyin cuta. Kwayar cutar da ka iya faruwa sun hada da:

• Jinin jini a kafafu, hannu ko huhu. Cikakken zai iya zama ko dai jijiyoyin jiki ko a jijiyoyin jini.
• Rashin ɓarkewar haihuwa ko haihuwa.
• Rash, a cikin wasu mutane.

A cikin wasu lamura da ba kasafai suke faruwa ba, farat-da-ƙulli ba zato ba tsammani a cikin jijiyoyi da yawa na tsawon kwanaki. Wannan shi ake kira catastrophic anti-phospholipid syndrome (CAPS). Zai iya haifar da bugun jini da kuma daskararren ƙoda, hanta, da sauran gabobin cikin jiki, da kuma gyambon ciki a gabobin jiki.

Gwaje-gwajen cutar lupus anticoagulant da antiphospholipid antibodies za a iya yi lokacin da:

• Rashin jini wanda ba zato ba tsammani yana faruwa, kamar a cikin samari ko waɗanda ba su da wasu abubuwan haɗari na daskarewar jini.
• Mace tana da tarihin yawan asarar ciki.

Gwajin lupus anticoagulant gwaje-gwaje ne na daskare jini. Kwayoyin cutar antiphospholipid (aPL) suna haifar da gwajin ya zama marar kyau a cikin dakin gwaje-gwaje.

Nau'in gwajin daskarewa na iya hadawa da:

• Kunna lokaci thromboplastin mai aiki (aPTT)
• Russell viper dafin lokaci
• Gwajin hanawa na Thromboplastin

Hakanan za a yi gwaje-gwajen don antiphospholipid antibodies (aPL). Sun hada da:

• Anticardiolipin gwajin jikin mutum
• Antibodies zuwa beta-2-glypoprotein I (Beta2-GPI)

Mai kula da lafiyarku zai bincikar cututtukan antiphospholipid antibody syndrome (APS) idan kuna da tabbataccen gwaji don aPL ko lupus anticoagulant, kuma ɗayan ko fiye daga cikin abubuwan da ke faruwa:

• Jigon jini
• Maimaita zubar ciki

Jarabawa masu kyau suna buƙatar tabbatarwa bayan makonni 12. Idan kana da gwaji mai kyau ba tare da wasu sifofin cutar ba, ba zaka sami cutar ta APS ba.

Maganin APS an shirya shi ne don hana rikitarwa daga sabbin jini da ke daskararwa ko dasassu da ke kasancewa da girma. Kuna buƙatar ɗaukar wani nau'i na maganin rage jini. Idan kuma kuna da cutar rashin ƙarfi, kamar su lupus, kuna buƙatar kiyaye wannan yanayin kuma a cikin iko.

Ainihin maganin zai dogara ne da yadda yanayin ku yake da kuma rikitarwa da yake haifarwa.

MAGANAR ANTIPHOSPHOLIPID ANTIBODY (APS)

Gabaɗaya, zaku buƙaci magani tare da sikari na jini na dogon lokaci idan kuna da APS. Jiyya na farko na iya zama heparin. Ana ba da waɗannan magunguna ta hanyar allura.

A mafi yawan lokuta, ana fara warfarin (Coumadin), wanda ake bayarwa ta bakin, sannan a fara. Wajibi ne akai-akai a lura da matakin maganin hana yaduwar jini. Ana yin wannan galibi ta amfani da gwajin INR.

Idan kana da APS kuma kayi ciki, akwai buƙatar mai bibiyarka ya bibiye ka wanda ƙwararre ne a wannan yanayin. Ba za ku ɗauki warfarin a lokacin daukar ciki ba, amma a maimakon haka za a ba ku horon.

Idan kuna da SLE da APS, mai ba ku sabis zai kuma ba da shawarar ku sha hydroxychloroquine.

A halin yanzu, ba a ba da shawarar wasu nau'in magungunan rage jini.

CATASTROPHIC ANTIPHOSPHOLIPID Ciwon (CAPS)

Jiyya ga CAPS wanda ya haɗa da haɗuwa da maganin ƙarancin jini, yawan ƙwayoyin corticosteroids, da musayar plasma sun yi tasiri ga yawancin mutane. Wani lokaci ana amfani da IVIG, rituximab ko eculizumab don lokuta masu tsanani.

GWADA MAI INGANTA GA LUPUS ANTICOAGULANT KO APL

Ba za ku buƙaci magani ba idan ba ku da alamun bayyanar, asarar ciki, ko kuma idan ba ku taɓa samun jinin jini ba.

Auki matakai masu zuwa don taimakawa hana daskarewar jini daga samuwa:

• Guji yawancin kwayoyi masu hana haihuwa ko maganin hormone na menopause (mata).
• KADA KA shan taba ko amfani da wasu kayan taba.
• Tashi ka zagaya yayin dogon jirgi ko wani lokacin da zaka zauna ko kwanciya na dogon lokaci.
• Motsa idon sawun ka sama da kasa lokacin da baka iya motsawa.

Za a sanya muku magungunan rage jini (irin su heparin da warfarin) don taimakawa hana daskarewar jini:

• Bayan tiyata
• Bayan karayar kashi
• Tare da ciwon daji mai aiki
• Lokacin da kake buƙatar zama ko kwanciya na dogon lokaci, kamar lokacin zaman asibiti ko murmurewa a gida

Hakanan zaka iya buƙatar ɗaukar nauyin jini na tsawon makonni 3 zuwa 4 bayan tiyata don rage haɗarin daskarewar jini.

Ba tare da magani ba, mutanen da ke tare da APS za su maimaita daskarewa. Mafi yawan lokuta, sakamako yana da kyau tare da magani mai kyau, wanda ya haɗa da maganin ƙwanƙwasa na dogon lokaci. Wasu mutane na iya samun daskarewar jini wanda ke da wuyar sarrafawa duk da jiyya. Wannan na iya haifar da CAPS, wanda ka iya zama barazanar rai.

Kira mai ba ku sabis idan kun lura alamun bayyanar raunin jini, kamar:

• Kumburi ko ja a kafa
• Rashin numfashi
• Jin zafi, dushewa, da launi mai launi a hannu ko kafa

Har ila yau, yi magana da mai ba ku idan kuna yawan asarar ciki (ɓarin ciki).

Anticardiolipin kwayoyin cuta; Ciwon Hughes

• Tsarin lupus erythematosus rash akan fuska
• Jinin jini

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Cibiyar Zuciya ta Kasa, huhu, da gidan yanar gizo. Antiphospholipid cututtukan antibody. www.nhlbi.nih.gov/health-topics/antiphospholipid-antibody-syndrome. An shiga Yuni 5, 2019.