C1 mai hana yaduwa

C1 esterase inhibitor (C1-INH) furotin ne wanda aka samu a sashin ruwan jinin ku. Yana sarrafa furotin da ake kira C1, wanda wani ɓangare ne na tsarin haɓaka.

Tsarin haɓaka shine rukuni na kusan sunadarai 60 a cikin jinin jini ko a saman wasu ƙwayoyin. Protearin sunadaran suna aiki tare da garkuwar jikinku don kare jiki daga kamuwa da cuta. Suna kuma taimakawa cire matattun ƙwayoyin da kayan ƙetare. Akwai manyan manyan sunadarai guda tara. Ana yi musu alama C1 ta hanyar C9. Ba da daɗewa ba, mutane na iya gaji rashi na wasu haɓakar sunadarai. Wadannan mutane suna da saukin kamuwa da wasu cututtuka ko kuma cutar ta jiki.

Wannan labarin yayi magana akan gwajin da aka yi don auna adadin C1-INH a cikin jinin ku.

Ana bukatar samfurin jini. Wannan galibi ana ɗauka ta jijiya. Ana kiran hanyar da ake kira venipuncture.

Ba a buƙatar shiri na musamman.

Lokacin da aka saka allurar don zana jini, wasu mutane suna jin matsakaicin ciwo. Wasu kuma ba sa jin wani abu kamar harbawa ko wani abu mai zafi. Bayan haka, ana iya samun wasu buguwa.

Kuna iya buƙatar wannan gwajin idan kuna da alamun gado ko ciwon angioedema. Dukkanin sifofin angioedema suna faruwa ne ta ƙananan matakan C1-INH.

Factorsarin abubuwan haɓaka na iya zama mahimmanci a gwaji don cututtukan ƙwayar cuta, kamar su lupus erythematosus.

Jeri na darajar yau da kullun na iya ɗan bambanta kaɗan tsakanin ɗakunan gwaje-gwaje daban-daban. Mai kula da lafiyar ku kuma zai auna matakin aiki na mai hana ku C1 esterase. Yi magana da mai baka game da ma'anar takamaiman sakamakon gwajin ka.

Levelsananan matakan C1-INH na iya haifar da wasu nau'ikan angioedema. Angioedema yana haifar da kumburin kyallen takarda na fuska, maƙogwaron sama da harshe. Hakanan yana iya haifar da wahalar numfashi. Hakanan kumburi a cikin hanji da ciwon ciki na iya faruwa. Akwai nau'ikan angioedema guda biyu wanda ke haifar da raguwar matakan C1-INH. Angioedema da ake gado yana shafar yara da samari 'yan ƙasa da shekara 20. Ana ganin angioedema da aka samu a cikin manya da suka girmi shekaru 40. Manya da ke fama da cutar angioedema suna da yiwuwar samun wasu yanayin kamar su kansa ko cutar kansa.

Hadarin da ke tattare da jan jini ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Hematoma (jini yana taruwa a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

C1 factor mai hanawa; C1-INH

• Gwajin jini

Cicardi M, Aberer W, Banerji A, et al. Rarrabuwa, ganewar asali, da kuma kusanci don maganin angioedema: rahoton yarjejeniya daga Workingungiyar Aiki ta ioasashen Duniya na eredasashe. Allergy. 2014; 69 (5): 602-616. PMID: 24673465 www.ncbi.nlm.nih.gov/pubmed/24673465.

Leslie TA, Greaves MW. Angioedema na gado. A cikin: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson IH, eds. Jiyya na cututtukan fata: Dabarun Magungunan Mahimmanci. 5th ed. Philadelphia, PA: Elsevier; 2018: babi na 101.

Zanichelli A, Azin GM, Wu MA, et al. Ganewar asali, hanya, da kuma kula da angioedema a cikin marasa lafiya tare da rashi mai hana C1. J Rashin lafiyar Clin Immunol Pract. 2017; 5 (5): 1307-1313. PMID: 28284781 www.ncbi.nlm.nih.gov/pubmed/28284781.