Mawallafi: Peter Berry
Ranar Halitta: 12 Yuli 2021
Sabuntawa: 14 Nuwamba 2024
Anonim
Approach from bedside to the etiology and pathogenesis of adult-onset Still’s disease
Video: Approach from bedside to the etiology and pathogenesis of adult-onset Still’s disease

Wadatacce

Gabatarwa

Rheumatoid amosanin gabbai (RA) cuta ce ta rashin lafiyar autoimmune. Yana haifar da tsarin garkuwar ku don afkawa lafiyayyun kyallen takarda a cikin gidajen ku, wanda ke haifar da ciwo, kumburi, da taurin kai. Ba kamar osteoarthritis ba, wanda ke haifar da lalacewa ta yau da kullun yayin da kuka tsufa, RA na iya shafar kowa a kowane zamani. Babu wanda ya san ainihin abin da ke haifar da shi.

RA ba shi da magani, amma magunguna na iya taimakawa bayyanar cututtuka. Wadannan magunguna sun hada da kwayoyi masu kashe kumburi, corticosteroids, da magungunan da ke danne tsarin garkuwar jiki. Wasu daga cikin magungunan magungunan da suka fi dacewa sune cututtukan cututtukan cututtukan ƙwayoyin cuta (DMARDs), waɗanda suka haɗa da masu hana TNF-alpha.

DMARDs: Mahimmanci a farkon jiyya

DMARDs magunguna ne waɗanda masana ilimin rheumatologists galibi ke ba da umurni daidai bayan ganewar asali na RA. Mafi yawan lalacewar haɗin gwiwa na dindindin daga RA yana faruwa ne a cikin shekaru biyu na farko, don haka waɗannan kwayoyi na iya yin babban tasiri a farkon lokacin cutar.

DMARDs suna aiki ta hanyar raunana garkuwar ku. Wannan aikin yana rage harin RA akan ɗakunan ku don rage yawan lalacewar.


Misalan DMARD sun haɗa da:

  • methotrexate (Otrexup)
  • hydroxychloroquine (Wuta)
  • tumatur (Arava)

DMARDs tare da maganin kashe zafin ciwo

Babban fa'ida don amfani da DMARDs shine suna jinkirin aiki. Zai iya ɗaukar watanni da yawa don jin duk wani ciwo mai sauƙi daga DMARD. Saboda wannan dalili, likitocin rheumatologists sukan ba da umarni masu saurin shan azaba kamar corticosteroids ko nonsteroidal anti-inflammatory anti-inflammatory (NSAIDs) don ɗauka a lokaci guda. Wadannan kwayoyi na iya taimakawa rage zafi yayin da kake jiran DMARD yayi tasiri.

Misalan corticosteroids ko NSAIDs waɗanda za'a iya amfani dasu tare da DMARD sun haɗa da:

Corticosteroids

  • prednisone (Rayos)
  • methylprednisolone (Depo-Madrol)
  • babancinolone (Aristospan)

NSAIDs da ke kan gaba

  • asfirin
  • ibuprofen
  • naproxen sodium

Takaddun NSAIDs

  • nabumetone
  • celecoxib (Celebrex)
  • piroxicam (Feldene)

DMARDs da cututtuka

DMARDs suna shafar dukkan garkuwar ku. Wannan yana nufin sun sanya ku cikin haɗarin kamuwa da cuta.


Mafi yawan cututtukan da marasa lafiyar RA ke da su sune:

  • cututtukan fata
  • cututtuka na numfashi na sama
  • namoniya
  • cututtukan fitsari

Don taimakawa rigakafin kamuwa da cuta, ya kamata ku yi amfani da tsafta mai kyau, gami da wanke hannuwanku koyaushe da yin wanka kowace rana ko kowace rana. Hakanan ya kamata ku nisanci mutanen da basu da lafiya.

Masu hana TNF-alpha

Tumor necrosis factor alpha, ko TNF alpha, wani abu ne wanda ke faruwa ta jiki cikin jikinku. A cikin RA, ƙwayoyin garkuwar jiki waɗanda ke kai hari ga ɗakunan mahaɗa suna haifar da matakan TNF alpha mafi girma. Wadannan manyan matakan suna haifar da ciwo da kumburi. Duk da yake wasu abubuwan da yawa suna ƙara wa RA lalacewa a cikin ɗakunan, TNF alpha shine babban ɗan wasa a cikin aikin.

Saboda TNF alpha babbar matsala ce a RA, masu hana TNF-alpha ɗayan mahimman nau'ikan DMARDs ne a kasuwa a yanzu.

Akwai nau'ikan masu hana TNF-alpha guda biyar:

  • adalimumab (Humira)
  • karban bayanai (Enbrel)
  • cergolizumab pegol (Cimzia)
  • golimumab (Simponi)
  • infliximab (Remicade)

Wadannan kwayoyi ana kiransu TNF-alpha blockers saboda suna toshe ayyukan TNF alpha. Suna rage matakan alpha na TNF a cikin jikinku don taimakawa rage alamun RA. Sun kuma fara aiki da sauri fiye da sauran DMARDs. Suna iya fara fara aiki tsakanin makonni biyu zuwa wata.


Yi magana da likitanka

Yawancin mutane tare da RA suna amsawa da kyau ga masu hanawa na TNF-alpha da sauran DMARDs, amma ga wasu mutane, waɗannan zaɓuɓɓukan na iya aiki ba kwata-kwata. Idan ba suyi muku aiki ba, ku gaya wa likitan kumburi. Wataƙila za su rubuta wani mai hana TNF-alpha a matsayin mataki na gaba, ko kuma suna iya ba da shawarar wani nau'in DMARD gaba ɗaya.

Tabbatar da sabunta likitan kumburi game da yadda kuke ji da kuma yadda kuke tsammani magungunan ku suna aiki. Tare, ku da likitan ku na iya samun tsarin RA wanda zai yi aiki a gare ku.

Tambaya:

Abinci na zai iya shafar RA na?

A:

Ee. Akwai abinci da yawa wadanda zasu iya taimakawa rage kumburi a jikinka. Idan kana son gwada sauye-sauyen abinci don inganta cututtukan RA, fara da cin abinci mai yawa wanda ya ƙunshi omega-3 fatty acid, antioxidants, da fiber, kamar kwayoyi, kifi, 'ya'yan itace, kayan lambu, da kuma koren shayi. Wata hanya mai kyau don kawo waɗannan abinci a cikin aikinku na yau da kullun shine bin abincin Rum. Don ƙarin bayani game da wannan abincin da sauran abinci waɗanda zasu iya taimakawa sauƙaƙe alamun RA, bincika tsarin rage kumburi na RA.

Amsoshin Teamungiyar Kiwon Lafiya na Lafiya suna wakiltar ra'ayoyin ƙwararrun likitocin mu. Duk abubuwan da ke ciki cikakkun bayanai ne kuma bai kamata a ɗauki shawarar likita ba.

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