Binciken CPK: menene don kuma me yasa aka canza shi
Wadatacce
Creatinophosphokinase, wanda aka sani da gajeriyar kalma CPK ko CK, enzyme ne wanda ke aiki akasari akan ƙwayoyin tsoka, kwakwalwa da zuciya, kuma ana buƙatar sashi don bincika yiwuwar lalacewar waɗannan gabobin.
Likita na iya yin odar wannan gwajin lokacin da mutum ya isa asibiti yana korafin ciwon kirji ko kuma duba alamun bugun jini ko wata cuta da ta shafi tsoka, misali.
Abubuwan bincike
Valuesididdigar tunani don halittar phosphokinase (CPK) sune 32 da 294 U / L don maza kuma 33 zuwa 211 U / L ga mata amma suna iya bambanta dangane da dakin gwaje-gwaje inda aka gudanar da gwajin.
Menene don
Gwajin creatinophosphokinase (CPK) yana da amfani don taimakawa cikin ganewar cututtuka irin su infarction, koda ko rashin ƙarfin huhu, da sauransu. Wannan enzyme ya kasu kashi uku bisa ga yadda yake:
- CPK 1 ko BB: Ana iya samun sa a cikin huhu da ƙwaƙwalwa, galibi;
- CPK 2 ko MB: Ana samun sa a cikin jijiyar zuciya don haka ana iya amfani da shi azaman alamar rashin ƙarfi, misali;
- CPK 3 ko MM: Yana nan a jikin tsoka kuma yana wakiltar kashi 95% na dukkanin halittun phosphokinases (BB da MB).
Sashin kowane nau'in CK ana yin shi ta hanyoyi daban-daban na dakin gwaje-gwaje bisa ga kaddarorin sa kuma bisa ga alamun likita. Lokacin da aka buƙaci sashi na CPK don tantance haɓakar cuta, misali, ana auna CK MB ban da sauran alamomin zuciya, kamar su myoglobin da troponin, galibi.
Consideredimar CK MB daidai take da ko ƙasa da 5 ng / mL ana ɗauka ta al'ada kuma yawanta yawanci yana sama yayin faruwar zuciya. Matakan CK MB yawanci suna ƙaruwa 3 zuwa 5 awanni bayan infarction, ya kai kololuwa har zuwa awanni 24 kuma ƙimar ta dawo daidai tsakanin sa'o'i 48 zuwa 72 bayan infarction. Duk da cewa ana dauke shi a matsayin alama mai kyau ta zuciya, dole ne a auna ma'aunin CK MB don gano cutar infarction tare da troponin, galibi saboda dabi'un troponin sun koma yadda suke yau kimanin kwanaki 10 bayan cutarwar, kasancewar, saboda haka, yafi takamaiman bayani. Duba abin da gwajin troponin yake don.
Me ma'anar CPK mai girma da ƙasa
Concentrationara yawan hankali na enzyme na halitta na iya nunawa:
| Babban CPK | CPananan CPK | |
| CPK BB | Infarction, bugun jini, ciwan ƙwaƙwalwa, kamuwa, gazawar huhu | -- |
| CPK MB | Inflammationonewar zuciya, raunin kirji, girgizar lantarki, idan akasari lalata zuciya, tiyatar zuciya | -- |
| MM CPK | Cutar raunin jiki, motsa jiki mai ƙarfi, motsa jiki tsawon lokaci, amfani da haramtattun magunguna, kumburi a cikin jiki, dystrophy na muscular, bayan electromyography | Rashin ƙwayar tsoka, cachexia da rashin abinci mai gina jiki |
| Jimlar CPK | Yawan shan giya, saboda amfani da magunguna kamar su amphotericin B, clofibrate, ethanol, carbenoxolone, halothane da succinylcholine da ake gudanarwa tare, guba tare da barbiturates | -- |
Don yin dokin CPK, yin azumi ba tilas bane, kuma likita na iya ko bazai bada shawara ba, duk da haka yana da mahimmanci a guji yin motsa jiki na motsa jiki na akalla kwanaki 2 kafin yin gwajin, saboda wannan enzyme na iya dagawa bayan motsa jiki saboda don samarwa ta tsokoki, ban da dakatar da magunguna, kamar su Amphotericin B da Clofibrate, misali, saboda suna iya tsoma baki tare da sakamakon gwajin.
Idan ana neman jarrabawa da nufin gano cutar bugun zuciya, ana bada shawara cewa a kimanta alakar da ke tsakanin CPK MB da CPK ta amfani da wannan hanyar: 100% x (CK MB / CK total). Idan sakamakon wannan dangantakar ya fi 6% girma, to yana nuni ne da raunin jijiyoyin zuciya, amma idan bai kai kasa da 6% ba, to alama ce ta raunin jijiyoyin jiki, kuma ya kamata likita ya binciko dalilin.
Tabbatar Duba
Sauya bawul aortic valve
