Rashin gashi da testosterone

Wadatacce

• Hanyoyi daban-daban na testosterone
• Siffar baldness
• DHT: Halin da ke bayan asarar gashi
• DHT da sauran sharuɗɗa
• Kwayoyin ku ne
• Tatsuniyoyi: Rashin hankali da zubar gashi
• Rashin gashi a cikin mata
• Magunguna don asarar gashi

Hadadden saƙa

Halin da ke tsakanin testosterone da asarar gashi yana da rikitarwa. Wani sanannen imani shine cewa maza masu sanƙo suna da matakan testosterone masu yawa, amma shin wannan gaskiyane?

Namiji irin na maza, ko kuma inrogenic alopecia, yana shafar kimanin maza miliyan 50 da mata miliyan 30 a cikin Amurka, a cewar Cibiyar Kula da Lafiya ta (asa (NIH). Rashin gashi yana faruwa ne saboda raguwar gashin kan mutum da kuma sakamakon da yake haifarwa akan ci gaban girma. Sabbin gashi sun zama masu kyau da kyau har zuwa lokacin da babu sauran gashi kwata-kwata kuma foll din sun zama basuyi bacci ba. Wannan asarar gashi yana faruwa ne ta hanyar hormones da wasu kwayoyin halitta.

Hanyoyi daban-daban na testosterone

Testosterone ya wanzu a jikinku ta hanyoyi daban-daban. Akwai testosterone "kyauta" wanda ba a ɗaure shi da sunadarai a jikinku ba. Wannan nau'in testosterone ne mafi samuwa don aiki a cikin jiki.

Hakanan ana iya ɗaura testosterone zuwa albumin, furotin a cikin jini. Yawancin testosterone suna ɗaure da jima'i na hormone-ɗaure globulin (SHBG) kuma baya aiki. Idan kuna da ƙananan matakin SHBG, kuna iya samun babban matakin testosterone kyauta a cikin jinin ku.

Dihydrotestosterone (DHT) an yi shi ne daga testosterone ta wani enzyme. DHT ya fi ƙarfin testosterone sau biyar. DHT da farko jiki yana amfani dashi a cikin prostate, fata, da gashin gashi.

Siffar baldness

Namiji irin na miji (MPB) yana da sifa iri-iri. Layin gashi na gaba yana ja baya, musamman a gefuna, yana yin fasalin M. Wannan karancin gashin kansa ne. Gwanin kai, wanda aka fi sani da lakabi, ya zama mai sanƙo kuma. Daga ƙarshe yankuna biyu sun shiga cikin sifar "U". MPB na iya ƙara zuwa gashin kirji, wanda zai iya siririri yayin da kuka tsufa. Ba daidai ba, gashi a wurare daban-daban a jiki na iya amsawa daban zuwa canjin hormonal. Misali, ci gaban gashin fuska na iya inganta yayin da sauran yankuna suka zama baƙi.

DHT: Halin da ke bayan asarar gashi

Dihydrotestosterone (DHT) an yi shi ne daga testosterone ta wani enzyme da ake kira 5-alpha reductase. Hakanan za'a iya yin shi daga DHEA, wani hormone wanda yafi kowa cikin mata. Ana samun DHT a fatar jiki, da gashin bakin gashi, da kuma prostate. Ayyukan DHT da ƙwarin jijiyoyin gashi ga DHT shine ke haifar da asarar gashi.

DHT kuma yana aiki a cikin prostate. Ba tare da DHT ba, ƙwayar prostate ba ta ci gaba kullum. Tare da DHT da yawa, wani mutum na iya haifar da hauhawar jini na prostate, wanda aka fi sani da ƙara girman prostate.

DHT da sauran sharuɗɗa

Akwai wasu shaidu na alaƙa tsakanin baƙon fata da sankara da sauran cututtuka. Makarantar Koyon Kiwon Lafiya ta Harvard ta ba da rahoton cewa maza masu fama da cutar sankarau suna da haɗarin kamuwa da cutar sankara ta jiki fiye da maza ba tare da tabo ba. Haɗarin cututtukan jijiyoyin jijiyoyin jini ya kuma fi kashi 23 cikin ɗari a cikin maza masu alaƙa da tabo. Ana ci gaba da bincike kan ko akwai hanyar haɗi tsakanin matakan DHT da cututtukan rayuwa, ciwon sukari, da sauran yanayin kiwon lafiya.

Kwayoyin ku ne

Ba yawan testosterone ko DHT ba ne ke haifar da rashin ƙarfi; yana da mahimmancin tasirin gashin ku. Wannan ƙwarewar yana ƙaddara ta hanyar kwayoyin halitta. Kwayar AR ta sa mai karɓa a kan raƙuman gashi wanda ke hulɗa tare da testosterone da DHT. Idan masu karɓar ku suna da mahimmanci, suna da sauƙi ta hanyar ko da ƙananan DHT, kuma asarar gashi yana faruwa cikin sauƙi sakamakon haka. Sauran kwayoyin halitta na iya taka rawa.

Shekaru, damuwa, da sauran abubuwan na iya yin tasiri ko kun sami asarar gashi. Amma kwayoyin halitta suna taka muhimmiyar rawa, kuma maza waɗanda suke da dangi na kusa da MPB suna da haɗarin haɓaka MPB da kansu.

Tatsuniyoyi: Rashin hankali da zubar gashi

Akwai tatsuniyoyi da yawa daga can game da maza masu yin baling. Ofayan su shine maza da ke da MPB sun fi ƙarfin zuciya kuma suna da matakan testosterone mafi girma. Wannan ba lallai bane lamarin. Maza tare da MPB na iya samun ƙananan matakan yaduwar testosterone amma matakan mafi girma na enzyme wanda ke canza testosterone zuwa DHT. Madadin haka, ƙila kuna da ƙwayoyin halitta waɗanda ke ba ku ƙwayoyin gashi waɗanda ke da matukar damuwa ga testosterone ko DHT.

Rashin gashi a cikin mata

Mata na iya fuskantar asarar gashi saboda asrogenetic alopecia. Kodayake mata suna da ƙananan matakan testosterone fiye da maza, akwai isa ga yiwuwar haifar da asarar asrogenetic gashi.

Mata suna fuskantar wani salon na rashin gashi. Bugun ciki yana faruwa a saman saman fatar kan cikin tsarin "bishiyar Kirsimeti", amma layin gashi na gaba baya komawa. Rashin asarar gashi na mata (FPHL) shima saboda ayyukan DHT ne akan gashin gashi.

Magunguna don asarar gashi

Hanyoyi da yawa na magance MPB da FPHL sun haɗa da tsoma baki tare da ayyukan testosterone da ayyukan DHT. Finasteride (Propecia) magani ne wanda ke hana 5-alpha reductase enzyme wanda ke canza testosterone zuwa DHT. Yana da haɗari a yi amfani da shi a cikin mata waɗanda ke iya yin ciki, kuma akwai yiwuwar illar jima’in wannan maganin akan maza da mata.

Wani 5-alpha reductase mai hanawa wanda ake kira dutasteride (Avodart) a halin yanzu ana duban shi azaman magani na MPB. A halin yanzu yana kan kasuwa don maganin ƙara girman prostate.

Sauran zaɓuɓɓukan magani waɗanda ba su ƙunshi testosterone ko DHT sun haɗa da:

• minoxidil (Rogaine)
• ketoconazole
• maganin laser
• tiyatar gashi follicle dashi