Shan Biologics da Sake Gudanar da Gudanar da Abun Cikinku na Psoriatic

Wadatacce

• Menene ilimin ilimin halittu?
• Nau'in ilimin halittu
• Abatacept
• Adalimumab
• Certolizumab pegol
• Saukewa
• Golimumab
• Infliximab
• Ustekinumab
• Haɗuwa hanyoyin kwantar da hankali
• Illoli da gargaɗi
• Ilimin ilimin halittu wani bangare ne na tsarin gudanarwa na PsA

Bayani

Cututtukan zuciya na Psoriatic (PsA) cuta ce ta yau da kullun, kuma ana buƙatar ci gaba da ci gaba don hana lalacewar haɗin gwiwa na dindindin. Maganin da ya dace zai iya sauƙaƙe adadin cututtukan arthritis.

Ilimin ilimin halittu shine nau'in magani guda ɗaya da ake amfani dashi don magance PsA. Wadannan suna aiki ne ta hanyar danne tsarin garkuwar jikinka don haka ya daina kaiwa gidajen abinci lafiya da haifar da ciwo da lalacewa.

Menene ilimin ilimin halittu?

Ilimin halittu shine nau'ikan cututtukan cututtukan ƙwayoyin cuta (DMARDs). DMARDs suna dakatar da tsarin ku na rigakafi daga haifar da kumburin PsA da sauran yanayin rashin lafiyar jiki.

Rage kumburi yana da manyan illa biyu:

• Zai yiwu a sami ƙaramin ciwo saboda kumburi a wuraren haɗin gwiwa shine asalin dalilin haɗin gwiwa.
• Ana iya rage girman lalacewa.

Biologics suna aiki ta hanyar toshe tsarin sunadarai wadanda ke haifar da kumburi. Ba kamar wasu DMARDs ba, ana gudanar da ilimin halittu ne ta hanyar jiko ko allura kawai.

An tsara ilimin ilimin halittu a matsayin layin farko don mutanen da ke da PsA mai aiki. Idan ilimin halittar farko da kuka gwada baya taimakawa alamomin ku, likitan ku na iya canza ku zuwa wani magani daban a cikin wannan ajin.

Nau'in ilimin halittu

Ana amfani da nau'o'in ilmin halitta guda huɗu don magance PsA:

• ƙari necrosis factor-alpha (TNF-alpha) masu hanawa: adalimumab (Humira), certolizumab pegol (Cimzia), etanercept (Enbrel), golimumab (Simponi Aria), infliximab (Remicade)
• interleukin 12/23 (IL-12/23) masu hanawa: ustekinumab (Stelara)
• interleukin 17 (masu hana IL-17): ixekizumab (Taltz), secukinumab (Cosentyx)
• T masu hana ƙwayoyin cuta: abatacept (Orencia)

Wadannan kwayoyi ko dai toshe takamaiman sunadaran da ke nuna maka tsarin garkuwar ka don kai hari ga kwayoyin halitta masu lafiya, ko kuma su yi niyya ga kwayoyin kariya wadanda ke da hannu a cikin amsar kumburin. Manufar kowane nau'in ilimin kimiya shine hana hana tsarin kumburi farawa.

Akwai ilimin ilimin halittu da yawa. Wadannan su ne mafi yawan lokuta waɗanda aka tsara don PsA.

Abatacept

Abatacept (Orencia) mai hana kwayar T ne. Kwayoyin T sune kwayoyin farin jini. Suna taka rawa a cikin martani na rigakafi, da kuma haifar da kumburi. Orencia tana ƙaddamar da ƙwayoyin T don kawo ƙonewa.

Orencia kuma yana magance cututtukan cututtukan rheumatoid (RA) da cututtukan yara na idiopathic (JIA). Ana samunsa azaman jiko ta jijiya, ko azaman allurar da kuka yiwa kanku.

Adalimumab

Adalimumab (Humira) yana aiki ta toshe TNF-alpha, furotin da ke inganta ƙonewa. Mutanen da ke da PsA suna yin TNF-alpha da yawa a cikin fata da haɗin gwiwa.

Humira magani ne na allura. An kuma wajabta shi don cutar Crohn da sauran nau'ikan cututtukan zuciya.

Certolizumab pegol

Certolizumab pegol (Cimzia) wani magani ne na TNF-alpha. An tsara shi don magance nau'ikan nau'ikan cutar PsA, da cututtukan Crohn, RA, da kuma ankylosing spondylitis (AS).

Cimzia ana ba ta kamar allurar kai.

Saukewa

Etanercept (Enbrel) shima magani ne na TNF-alpha. Yana daga cikin tsofaffin magungunan da aka yarda dasu don maganin PsA, kuma ana amfani dashi don magance wasu nau'ikan cututtukan zuciya.

Enbrel ana yin allurar kai sau ɗaya sau biyu a mako.

Golimumab

Golimumab (Simponi) magani ne na TNF-alpha wanda aka tsara don magance PsA mai aiki. An kuma tsara shi don matsakaici-zuwa-mai tsanani RA, ulcerative ulcerative colitis (UC), da AS mai aiki.

Kuna shan Simponi sau ɗaya a wata ta hanyar allurar kai.

Infliximab

Infliximab (Remicade) sigar jiko ce ta maganin TNF-alpha. Kuna samun jiko a ofishin likita sau uku a cikin makonni shida. Bayan jiyya na farko, ana ba da jiko kowane wata biyu.

Remicade yana magance cutar Crohn, UC, da AS. Doctors na iya tsara shi don RA, tare da methotrexate.

Ixekizumab

Ixekizumab (Taltz) shine mai hana IL-17. Yana toshe IL-17, wanda ke ƙunshe cikin amsawar kumburi na jiki.

Kuna samun Taltz azaman jerin allurai ƙarƙashin fata kowane sati biyu, sannan kowane sati huɗu.

Secukinumab

Secukinumab (Cosentyx) wani mai hana IL-17 ne. An yarda dashi don magance psoriasis da PsA, da AS.

Kuna ɗauka azaman harbi a ƙarƙashin fatarka.

Ustekinumab

Ustekinumab (Stelara) mai hanawa IL-12/23 ne. Yana toshe sunadaran IL-12 da IL-23, wanda ke haifar da kumburi a cikin PsA. Stelara an yarda da ita don magance PsA mai aiki, rubutun almara, da cutar Crohn mai matsakaici-zuwa-mai tsanani.

Stelara ta zo a matsayin allura. Bayan allurar farko, ana sake yin ta bayan sati hudu, sannan sau ɗaya a kowane mako 12.

Haɗuwa hanyoyin kwantar da hankali

Don matsakaici zuwa mai tsanani PsA, ilimin ilimin halittu yana da mahimmanci wajen sarrafa alamun gajere da na dogon lokaci da rikitarwa. Koyaya, likitanku na iya bayar da shawarar wasu jiyya.

Likitan ku na iya bada umarnin wasu cututtukan cututtukan cututtukan cututtukan cututtukan ƙwayoyin cuta (NSAIDs) don ciwon haɗin gwiwa. Wadannan kuma suna rage kumburi. Versionsarin kan-kan-kan (OTC), kamar su ibuprofen (Advil), ana samun su ko'ina, har ma da dabarun da ake bi da su.

Tun da amfani na dogon lokaci na iya ƙara haɗarin zub da jini na ciki, matsalolin zuciya, da bugun jini, yakamata a yi amfani da NSAIDs a hankali kuma a mafi ƙarancin abin da zai yiwu.

Idan kuna da cutar psoriasis kafin PsA, to kuna iya buƙatar hanyoyin kwantar da hankali don taimakawa sauƙaƙewar fata da matsalolin ƙusa. Zaɓuɓɓukan maganin da za su iya haɗawa sun haɗa da corticosteroids, far da ake amfani da su, da kuma man shafawa a cikin magani.

Illoli da gargaɗi

Illolin dake tattare da ilimin halittar jiki sune halayen fata (kamar su ja da kumburi) a wurin allurar. Saboda ilimin kimiyyar halittu suna sarrafa tsarin garkuwar ku, kuna iya kasancewa cikin haɗarin kamuwa da cututtuka.

Kadan na kowa, amma mai tsanani, illa masu illa sun haɗa da:

• damuwa psoriasis
• kamuwa da cuta ta sama
• tarin fuka
• cututtukan lupus-kamar (kamar tsoka da haɗin gwiwa, zazzabi, da zubewar gashi)

Yi magana da likitan ku game da waɗannan illolin, kuma kula da yanayinku da kyau. Kira nan da nan idan kun yi zargin kuna da mummunar tasiri ga magungunan ku.

Hakanan, matan da suke da ciki ko suke shirin yin ciki ya kamata suyi amfani da ilimin ilimin halitta tare da kulawa.

Kodayake ba a fahimci tasirin da ke kan jariri mai tasowa ba, akwai yiwuwar rikitarwa tare da juna biyu. Dangane da tsananin PsA, wasu likitoci sun ba da shawarar dakatar da magani yayin daukar ciki.

Ilimin ilimin halittu wani bangare ne na tsarin gudanarwa na PsA

Ilimin halittu ya kawo fata ga mutane da yawa tare da PsA. Ba wai kawai ilimin kimiyyar halittu ke taimakawa wajen sarrafa alamun PsA ba, har ila yau suna rage yanayin lalacewa na tushen kumburi.

Har yanzu, yana da mahimmanci a tuna cewa ilimin kimiyyar halittu wani bangare ne kawai na tsarin gudanarwar PsA na dogon lokaci. Yi magana da likitanka game da canjin rayuwa da sauran magunguna waɗanda zasu iya taimakawa.