Urease test: menene shi da yadda ake yin sa

Wadatacce

• Yadda ake yin gwajin
• Yadda za a fahimci sakamakon

Urease gwajin wani dakin gwaje-gwaje ne da ake amfani dashi dan gano kwayoyin cuta ta hanyar gano aikin wani enzyme wanda kwayoyin zasu iya ko kuma basu dashi. Urease enzyme ne wanda ke da alhakin lalata urea cikin ammoniya da bicarbonate, wanda ke ƙara pH na wurin da yake, yana fifita yaduwarsa.

Wannan gwajin ana amfani dashi galibi a cikin ganewar kamuwa da cuta ta Helicobacter pylori, ko H. pylori, wanda ke da alhakin matsaloli da yawa, irin su gastritis, esophagitis, duodenitis, ulcer da cancer na ciki, saboda wannan dalili. Don haka, idan akwai tuhuma game da kamuwa da cuta ta H. pylori, likitan ciki zai iya yin gwajin urease yayin endoscopy. Idan haka ne, ana farawa da sauri da nufin hana cutar ci gaba da saukaka alamomin mutum.

Yadda ake yin gwajin

Lokacin da aka yi gwajin urease azaman aikin dakin gwaje-gwaje, ba a buƙatar shiri don gwajin. Duk da haka, idan aka yi shi a lokacin endoscopy, yana da muhimmanci mutum ya bi duk ka'idojin gwajin, kamar gujewa amfani da kwayoyi masu guba da yin azumi na akalla awanni 8.

Ana yin gwajin urease a dakin gwaje-gwaje ta hanyar nazarin abubuwan da aka tattara, tare da kebewar kwayoyin halittar da ake yi da kuma gwajin gano biochemical, daga cikinsu akwai gwajin urease. Don yin gwajin, an keɓance ƙananan ƙwayoyin cuta cikin matsakaiciyar al'adar da ke ƙunshe da urea da phenol ja pH mai nuna alama. Bayan haka, ana bincika ko akwai canji a launi na matsakaici ko a'a, wanda ke nuna kasancewar da babu ƙwayoyin cuta.

Game da gwajin urease don gano kamuwa da cuta ta H. pylori, ana yin gwajin ne a lokacin babban gwajin endoscopy, wanda shine gwajin da ke kimanta lafiyar esophagus da ciki, ba tare da haifar da ciwo ko rashin jin daɗi ga mai haƙuri ba kuma ana iya kimanta sakamakon cikin fewan mintoci kaɗan. Yayin binciken, za a cire wani ɗan bangon ciki a saka shi a cikin leda mai ɗauke da urea da alamar pH. Idan bayan fewan mintoci matsakaici ya canza launi, ana faɗin gwajin ya zama urease tabbatacce, mai tabbatar da kamuwa da cuta ta H. pylori. Dubi waɗanne alamun alamun na iya nuna kamuwa da cuta ta H. pylori.

Yadda za a fahimci sakamakon

Sakamakon gwajin urease ana bayarwa daga canzawar launi na matsakaiciyar da ake yin gwajin a ciki. Don haka, sakamakon na iya zama:

• Tabbatacce, lokacin da kwayar da ke da enzyme urease ke iya kaskantar da urea, ta haifar da ammonia da bicarbonate, ana ganin wannan aikin ta canza launin mai matsakaici, wanda ke canzawa daga rawaya zuwa ruwan hoda / ja.
• Korau lokacin da babu canji a launi na matsakaici, yana nuna cewa kwayar cutar ba ta da enzyme.

Yana da mahimmanci a fassara sakamakon a cikin awanni 24 don kada a sami damar sakamakon sakamako na ƙarya, waɗanda sune saboda tsufan mai matsakaici, urea ya fara ƙasƙanci, wanda zai iya canza launi.

Baya ga gano kamuwa da cuta ta Helicobacter pylori, Ana yin gwajin urease don gano kwayoyin cuta da yawa, kuma gwajin ma tabbatacce ne ga Staphylococcus saprophyticus, Staphylococcus cututtukan fata, Proteus spp. kuma - Klebsiella ciwon huhu, misali.