Yaushe Magungunan Halittu Zaɓi ne don Cututtukan Crohn?

Wadatacce

• Menene magungunan ilimin halittu?
• Nau'o'in ilimin halittu guda uku
• Magungunan anti-TNF
• Masu hana interleukin
• Magungunan anti-integrin
• Mataki-sama da maganin sama-da-ƙasa
• Sakamakon sakamako
• Shawarwari na musamman
• Tarin fuka
• Cututtuka
• Yanayin zuciya
• Sauran batutuwa

Bayani

Cutar Crohn na haifar da kumburi, kumburi, da kuma damuwa a cikin rufin sashin narkewa.

Idan kun gwada wasu magunguna don cutar Crohn, ko ma idan kun sami sabon bincike, likitanku na iya yin la'akari da rubuta magungunan ilimin halittu. Ilimin ilimin halittu sune magungunan likita waɗanda ke taimakawa rage ƙonewa mai cutarwa daga cutar Crohn.

Menene magungunan ilimin halittu?

Biologics magunguna ne masu keɓaɓɓen ƙwayoyin cuta waɗanda ke ɗora kan wasu ƙwayoyin jikin da ke haifar da kumburi.

Doctors galibi suna ba da ilimin kimiyyar halittu ga waɗanda ke da ƙyamar cututtukan Crohn da ba ya amsa wasu magunguna, ko kuma ga mutanen da ke da mummunan cututtuka.Kafin ilimin ilimin halittu, akwai 'yan zaɓuɓɓukan maganin rashin kulawa marasa kyau don mutanen da ke da cutar rashin ƙarfi.

Magungunan ƙwayoyin cuta suna aiki don kawo saurin gafara. Yayin wani lokaci na gafara, kumburi da alamun hanji suna tafiya. Hakanan ana iya amfani da ilimin halittu akan lokaci mai tsawo don taimakawa kiyaye lokutan gafartawa.

Nau'o'in ilimin halittu guda uku

Nau'in ilimin likitancin da likitanku ya ba da shawara zai dogara ne da tsananin alamun alamunku da wurin cutar. Kowa daban yake. Wani magani na ilmin halitta na iya aiki mafi kyau ga wasu fiye da wasu. Wataƙila ku gwada medicationsan magunguna kafin ku sami abin da zai amfane ku.

Magungunan ilimin halittu don cututtukan Crohn sun faɗa cikin ɗayan rukunoni uku: maganin cututtukan necrosis (anti-TNF) hanyoyin kwantar da hankali, masu hana interleukin, da anti-integrin antibodies.

Magungunan anti-TNF sun ƙaddamar da furotin wanda ke cikin kumburi. Don cututtukan Crohn, hanyoyin kwantar da hankali na TNF suna aiki ta hanyar toshe kumburi wanda wannan furotin ya haifar a cikin hanji.

Masu hanawa na Interleukin suna aiki kamar haka, ta hanyar toshe sunadaran da ke faruwa a cikin ɗabi'a wanda ke haifar da kumburi a cikin hanjin. Anti-integrins suna toshe wasu ƙwayoyin garkuwar jiki waɗanda ke haifar da kumburi.

Ana ba da ilimin kimiyyar ilimin halitta ko dai ta hanyar subcutaneously (tare da allura ta cikin fata) ko cikin intravenously (ta hanyar bututun IV). Ana iya ba su kowane mako biyu zuwa takwas, ya dogara da magani. Dole ne ku je asibiti ko asibiti don yawancin waɗannan maganin.

FDA ta amince da magungunan ƙwayoyin cuta da yawa don magance cutar Crohn.

Magungunan anti-TNF

• adalimumab (Humira, Exemptia)
• cergolizumab pegol (Cimzia)
• infliximab (Remicade, Remsima, Inflectra)

Masu hana interleukin

• 'ustekinumab (Stelara)

Magungunan anti-integrin

• natalizumab (Tysabri)
• vedolizumab (Entyvio)

Mataki-sama da maganin sama-da-ƙasa

Magungunan ilimin halittu na iya zama kayan aiki mai ƙarfi a cikin kulawa da kula da cutar Crohn. Akwai hanyoyi daban-daban guda biyu don ilimin ilimin halittu:

• Matakan-mataki shine tsarin al'ada har zuwa lokacin da aka fitar da sababbin jagororin a cikin 2018. Wannan tsarin yana nufin cewa ku da likitan ku gwada wasu magunguna da yawa kafin fara ilimin halittu.
• Maganin sama zuwa ƙasa yana nufin cewa an fara amfani da magungunan ilimin halittu tun da wuri a cikin tsarin kulawa. Wannan yanzu shine hanyar da aka fi so a yawancin lokuta na matsakaici zuwa mai tsanani cutar Crohn.

Koyaya, hanyoyi daban-daban na iya aiki mafi kyau ga mutane daban-daban dangane da tsanani da wurin cutar.

Sakamakon sakamako

Ilimin ilimin halittu ya kasance yana da ƙananan sakamako masu illa waɗanda basu da tsayayyar rauni fiye da sauran magungunan cututtukan Crohn, kamar su corticosteroids, waɗanda ke hana dukkan garkuwar jiki.

Har yanzu, akwai wasu illolin da ya kamata ku sani game da kafin shan ilimin ilimin halitta.

Wasu sakamako masu illa na yau da kullun na ilimin ilimin halittu sun haɗa da:

• redness, itching, bruising, zafi, ko kumburi a kusa da wurin allurar
• ciwon kai
• zazzabi ko sanyi
• wahalar numfashi
• saukar karfin jini
• amya ko kurji
• ciwon ciki
• ciwon baya
• tashin zuciya
• tari ko ciwon wuya

Shawarwari na musamman

Ilimin ilimin halittu bazai iya zama aminci ga kowa ba. Yi magana da likitanka idan kana da tarin fuka (TB), mai saukin kamuwa da cuta, ko kuma kana da yanayin zuciya.

Tarin fuka

Magungunan ilimin halittu da ake amfani da su don cutar Crohn na iya ƙara haɗarin sake kunna kamuwa da cutar tarin fuka a cikin mutanen da aka fallasa. Tarin fuka cuta ce mai saurin kamuwa da cutar huhu.

Ya kamata likitanku ya gwada ku ga tarin fuka kafin fara maganin rayuwa. Kamuwa da cutar tarin fuka na iya zama barcin a jiki. Wasu mutanen da suka kamu da cutar bazai sani ba.

Idan kun taɓa yin kamuwa da cutar tarin fuka, likitanku na iya ba da shawarar maganin tarin fuka kafin ɗaukar ilimin halittu.

Cututtuka

Ilimin halittu zai iya rage karfin jiki don yakar sauran cututtuka. Idan kun kasance masu saurin kamuwa da cuta, likitanku na iya bayar da shawarar wani nau'in magani.

Yanayin zuciya

Magungunan anti-TNF na iya zama haɗari ga mutanen da ke da wasu yanayin zuciya, kamar ciwon zuciya. Ciwon zuciya shine lokacin da zuciya ba zata iya fitar da isasshen jini don biyan bukatun jiki ba.

Faɗa wa likitanku da wuri-wuri idan kun sami ƙarancin numfashi ko kumburin ƙafa yayin shan ilimin halittu game da cutar Crohn. Waɗannan na iya zama alamun bugun zuciya.

Sauran batutuwa

Magungunan ilimin ilimin halittu a wasu lokuta suna da alaƙa da manyan matsalolin lafiya. A cikin mutanen da ke shan magungunan ƙwayoyin cuta, ba a cika ba da rahoton matsalolin lafiya masu zuwa:

• wasu rikicewar jini (rauni, zub da jini)
• matsalolin jijiyoyin jiki (gami da, suma, rauni, rauni, ko damuwa, kamar hangen nesa, hangen nesa biyu, ko makauniyar ido)
• lymphoma
• hanta lalacewa
• mummunan rashin lafiyan halayen

Yi magana da likitanka don ƙayyade mafi kyawun magani don ku da bukatun ku.